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Full-Text Articles in Medicine and Health Sciences
Influence Of Walking Football On Decreasing Cholesterol And Blood Glycemic Level, Siswantoyo Siswantoyo, Kukuh Hardopo Putro, Japhet Ndayisenga, Rajesh Kumar, Rozita Abdul Latif
Influence Of Walking Football On Decreasing Cholesterol And Blood Glycemic Level, Siswantoyo Siswantoyo, Kukuh Hardopo Putro, Japhet Ndayisenga, Rajesh Kumar, Rozita Abdul Latif
Jurnal Keolahragaan
The aims of this research to determine the impact of walking football on cholesterol and glycemic management in order to allow people to live healthily. This research is an experimental study with quantitative approach. The research sampling was 12 subjects from different category: (1) International students, (2) Local students, and employed persons. Technique collecting data using playground of futsal to assess variables like glycemic and cholesterol. Data analysis using independent test sample. To evaluate the subjects' health condition, the research proceeded by pre-test first, for the second step a walking football was given during 12 weeks within 3 times per …
Preventing Cholesterol-Induced Perk (Protein Kinase Rna-Like Endoplasmic Reticulum Kinase) Signaling In Smooth Muscle Cells Blocks Atherosclerotic Plaque Formation, Abhijnan Chattopadhyay, Pujun Guan, Suravi Majumder, Kaveeta Kaw, Zhen Zhou, Chen Zhang, Siddharth K Prakash, Anita Kaw, L Maximillian Buja, Callie S Kwartler, Dianna M Milewicz
Preventing Cholesterol-Induced Perk (Protein Kinase Rna-Like Endoplasmic Reticulum Kinase) Signaling In Smooth Muscle Cells Blocks Atherosclerotic Plaque Formation, Abhijnan Chattopadhyay, Pujun Guan, Suravi Majumder, Kaveeta Kaw, Zhen Zhou, Chen Zhang, Siddharth K Prakash, Anita Kaw, L Maximillian Buja, Callie S Kwartler, Dianna M Milewicz
Journal Articles
BACKGROUND: Vascular smooth muscle cells (SMCs) undergo complex phenotypic modulation with atherosclerotic plaque formation in hyperlipidemic mice, which is characterized by de-differentiation and heterogeneous increases in the expression of macrophage, fibroblast, osteogenic, and stem cell markers. An increase of cellular cholesterol in SMCs triggers similar phenotypic changes in vitro with exposure to free cholesterol due to cholesterol entering the endoplasmic reticulum, triggering endoplasmic reticulum stress and activating Perk (protein kinase RNA-like endoplasmic reticulum kinase) signaling.
METHODS: We generated an SMC-specific
RESULTS: SMC-specific deletion of Perk reduces atherosclerotic plaque formation in male hyperlipidemic mice by 80%. Single-cell transcriptomic data identify 2 …
Familial Hypercholesterolemia And Treatments, Alexis Steer
Familial Hypercholesterolemia And Treatments, Alexis Steer
Williams Honors College, Honors Research Projects
My project will be a literature review regarding the genetic mutations associated with
familial hypercholesterolemia and the current available treatments.