Open Access. Powered by Scholars. Published by Universities.®
- Institution
- Publication Type
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Identifying Placebo Effects With Data From Clinical Trials, Anup Malani
Identifying Placebo Effects With Data From Clinical Trials, Anup Malani
Anup Malani
A medical treatment is said to have placebo effects if patients who are optimistic about the treatment respond better to the treatment. This paper proposes a simple test for placebo effects. Instead of comparing the treatment and control arms of a single trial, one should compare the treatment arms of two trials with different probabilities of assignment to treatment. If there are placebo effects, patients in the higher-probability trial will experience better outcomes simply because they believe that there is a greater chance of receiving treatment. This paper finds evidence of placebo effects in trials of antiulcer and cholesterol-lowering drugs.
Effects Of Excess Vitamin B_6 Intake On Serum Lipid Profile And Cerebral Cortex In Rats, Göksemi̇n Acar, Leyla Sati, Yasemi̇n Seval, Aysel Ağar, Ramazan Demi̇r
Effects Of Excess Vitamin B_6 Intake On Serum Lipid Profile And Cerebral Cortex In Rats, Göksemi̇n Acar, Leyla Sati, Yasemi̇n Seval, Aysel Ağar, Ramazan Demi̇r
Turkish Journal of Medical Sciences
Aim: The present study was undertaken to investigate the effects of dietary excess of vitamin B_6 on certain blood parameters [serum total cholesterol, high density lipoprotein (HDL) cholesterol and total lipid] and the cerebral cortex. Materials and Methods: A total of 36 albino rats were included in the study. Saline solution was administered to control groups (CG-10, n = 6 for 10 days; CG-15, n = 6 for 15 days; CG-20, n = 6 for 20 days). The experimental groups (EG-10, n = 6; EG-15, n = 6; EG-20, n = 6) received 5 mg/kg vitamin B_6 daily for 10 …