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Full-Text Articles in Medicine and Health Sciences
Gelatinase Activity In The Mouse Uterus During Early Pregnancy, Carol A. Brenner, Richard R. Adler, Gary L. Nieder
Gelatinase Activity In The Mouse Uterus During Early Pregnancy, Carol A. Brenner, Richard R. Adler, Gary L. Nieder
Gary L. Nieder
No abstract provided.
Can Small-Area Analysis Detect Variation In Surgery Rates? The Power Of Small-Area Variation Analysis., Paula Diehr
Can Small-Area Analysis Detect Variation In Surgery Rates? The Power Of Small-Area Variation Analysis., Paula Diehr
Paula Diehr
A variety of statistical methods can be used in small-area analysis to test whether there is more variation than would be expected by chance alone. However, the power of these methods to detect existing variation has never been studied. The authors used data regarding back surgery in Washington State to suggest several types of variation that might exist (alternative hypotheses), and then used computer simulation to determine the power, or the probability of detecting this variation. The chi-square test had the highest power of all methods considered against most alternative hypotheses. Power is higher if there are no multiple admissions, …
Animal Model Of Human Disease: Bovine Leukocyte Adhesion Deficiency: Beta2 Integrin Deficiency In Young Holstein Cattle, Marcus E. Kehrli Jr., Mark R. Ackermann, Dale E. Shuster, Martin J. Van Der Maaten, Frank C. Schmalstieg, Donald C. Anderson, Bonnie J. Hughes
Animal Model Of Human Disease: Bovine Leukocyte Adhesion Deficiency: Beta2 Integrin Deficiency In Young Holstein Cattle, Marcus E. Kehrli Jr., Mark R. Ackermann, Dale E. Shuster, Martin J. Van Der Maaten, Frank C. Schmalstieg, Donald C. Anderson, Bonnie J. Hughes
Mark R. Ackermann
Leukocyte adhesion deficiency (LAD), is a rare, autosomal recessive disorder caused by a lack or partial absence of a family of leukocyte integrins, Mac-1, LFA-1, and p150,95.1 The leukocyte (32) integrins are glycoproteins essential for normal leukocyte-endothelial cell adherence and emigration. Affected children develop recurrent bacterial infections, persistent leukocytosis, severe hypoplasia of lymphoid tissues and isolated neutrophils, eosinophils, macrophages, and lymphocytes have abnormal function when tested in vitro. Most patients without bone marrow transplants die at an early age.
The Saurian Psyche Revisted: Lizards In Research, Neil Greenberg
The Saurian Psyche Revisted: Lizards In Research, Neil Greenberg
Neil Greenberg
This essay is intended to guide researchers interested in lizards as prospective experimental models to identify an appropriate species for their research needs and to care for lizards in a manner that will not compromise their utility. Coupled with these is a concern for critical thinking about the ethical dimension of lizard research, one guide for which is to consider the intersection of human needs and lizard needs. Before proceeding further, several arbitrary premises must be made clear: 1. While wholly deserving of study because of their intrinsic interest, I will assume that the lizard research to be undertaken is …