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Full-Text Articles in Medicine and Health Sciences
Hook3 Mutations And Their Contributions To Different Types Of Cancers, Brittny Mikhaiel, Van Vo Ph.D.
Hook3 Mutations And Their Contributions To Different Types Of Cancers, Brittny Mikhaiel, Van Vo Ph.D.
Undergraduate Research Symposium Posters
Hook3 (Hook Microtubule Tethering Protein 3) is a gene that encodes a protein that is localized in the Golgi complex and is linked to cellular trafficking of cargos and the binding of microtubules to organelles. Although there is some literature discussing the known functions of the gene, the phenotypes in mice or humans have not been thoroughly researched and literature on these phenotypes is limited. The literature that is available suggests Hook3 is implicated in diverse phenotypes ranging from bone development to neural development in mice. Since Hook3 is associated with prostate cancer, it is likely that it is involved …
A Timeline Of Down Syndrome, Christian Guese, Kristina Mcinnes, Kimberly Miranda
A Timeline Of Down Syndrome, Christian Guese, Kristina Mcinnes, Kimberly Miranda
Undergraduate Research Symposium Posters
The purpose of this research timeline is to synthesize the natural history of Down Syndrome (DS) to discover absence of knowledge, discuss the bioethics in prenatal screening and develop a public health message. Our method of research was literature-based. DS is one of the most common aneuploidy disorders in the United States. There are three genetic variations of DS, Trisomy 21, a third copy of chromosome 21, accounts for 95% of cases. DS causes intellectual disability, developmental delays, facial dysmorphia, and low muscle tone. DS also leads to an increased risk for congenital heart defects and Alzheimer’s disease later in …
Discovering Rett Syndrome (Rts) And Understanding Its Enigmatic Development, Fiorella Ramirez-Guasp, Chanel Chan, Sukyeong Kim
Discovering Rett Syndrome (Rts) And Understanding Its Enigmatic Development, Fiorella Ramirez-Guasp, Chanel Chan, Sukyeong Kim
Undergraduate Research Symposium Posters
The purpose of this research project is to compose a comprehensive timeline on the rare disease Rett Syndrome (RTS) in order to better understand its enigmatic development as well as furthering the public’s understanding on this degenerative disease. RTS is a panethnic progressive neurodevelopmental disorder that occurs nearly exclusively in girls. This syndrome is characterized by normal prenatal and neonatal development, followed by an onset of neurological symptoms with a mental stagnation anywhere around 6-18 months of age that involves a rapid loss in speech and acquired motor skills. There is limited knowledge about the molecular cause of Rett Syndrome, …