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Full-Text Articles in Medicine and Health Sciences
9-Phenanthrol And Flufenamic Acid Inhibit Calcium Oscillations In Hl-1 Mouse Cardiomyocytes, Rees A. Burt
9-Phenanthrol And Flufenamic Acid Inhibit Calcium Oscillations In Hl-1 Mouse Cardiomyocytes, Rees A. Burt
Undergraduate Honors Theses
Electrical potentials exist across the membranes of nearly every cell type in the body. In addition, excitable cells, such as neurons, myocytes and even some endocrine cells elicit electrochemical fluctuations, action potentials (AP), in the cell membrane to initiate cell-to-cell communication or intracellular processes. The basis for the electrical potential is rooted within an array of complex interactions between monovalent ions and their associated membrane channels and transporters that regulate the flux of these charged species across the hydrophobic bilayer. Here, an expansion of our recently published work [1] will serve to explore the modern concepts regarding the …
Measuring The Effects Of Ctrp3 And Metformin On H4iie Hepatocyte Metabolism Using Seahorse Extracellular Flux Analyzer, Forrest J. Longway
Measuring The Effects Of Ctrp3 And Metformin On H4iie Hepatocyte Metabolism Using Seahorse Extracellular Flux Analyzer, Forrest J. Longway
Undergraduate Honors Theses
Non-alcoholic fatty liver disease (NAFLD) results from an unequal uptake/storage and export/oxidation of lipids within the liver and is often a secondary disease to type II diabetes (22). NAFLD causes this imbalance of lipids by altering glucose and lipid metabolism, which corresponds to a decrease in mitochondrial function leading to failure of the liver. One established treatment for type II diabetes and NAFLD is the drug metformin, which has similar properties to the newly discovered CTRP 3 protein which is part of a group of bioactive molecules secreted by adipose tissue, collectively termed adipokines (2-4). Both have similar effects on …