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Medical Sciences

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Open Access Dissertations

Theses/Dissertations

2009

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Full-Text Articles in Medicine and Health Sciences

Effects Of Sex And Social Status On Neuromuscular Differentiation In The Eusocial Naked Mole-Rat (Heterocephalus Glaber), Marianne Louise Seney Sep 2009

Effects Of Sex And Social Status On Neuromuscular Differentiation In The Eusocial Naked Mole-Rat (Heterocephalus Glaber), Marianne Louise Seney

Open Access Dissertations

Naked mole-rats live in large colonies and exhibit a strict reproductive hierarchy. Each colony has 1 breeding female and 1-3 breeding males; all other individuals are non-reproductive subordinates. Subordinates show a remarkable lack of sex differences in behavior and anatomy, but can become reproductive if removed from the colony. The striated perineal muscles and their innervating motoneurons, which are sexually dimorphic in all other mammals examined, are not dimorphic in subordinate naked mole-rats. Here I asked whether sexual differentiation of this neuromuscular system occurs when subordinates become breeders. Sex differences in perineal motoneurons were not observed, regardless of social status. …


Detrimental Effects Of Inactivity On Insulin Action, Brooke Rene Stephens May 2009

Detrimental Effects Of Inactivity On Insulin Action, Brooke Rene Stephens

Open Access Dissertations

Inactivity reduces insulin action. Energy surplus causes similar reductions to insulin action. Unless energy intake is reduced to match low energy expenditure during inactivity, a concurrent energy surplus may account for the lower insulin action. This study evaluated the effect of inactivity (sitting) with and without energy surplus on insulin action. Fourteen young (26.1 ± 4.5 years (M ± SD)), lean (23.7 ± 7.1% fat), fit (VO 2peak = 49.1 ± 3.3 ml*kg -1 *min -1 ) men (n=7) and women (n=7) completed each of 3, 24-hour conditions: an active condition (i.e. high energy expenditure with energy intake matched to …