Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- AS (1)
- Asperger syndrome (1)
- Biomedical Science (1)
- Cannabinoid (1)
- Cloning (1)
-
- Epigenetic regulation (1)
- Genetic counseling (1)
- HFA (1)
- High Functioning Autism (1)
- Human Granulosa Cells (1)
- Human STARD4 Transcripts (1)
- Immune functions (1)
- Ligands (1)
- Medicine and Health Sciences, Medical Sciences, Biomedical Science (1)
- Proteins in Human Ovarian Tissue (1)
- STARD4 (1)
- STARD6 (1)
- Support and services (1)
- THC (1)
- Tetrahydrocannabinol (1)
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Cannabinoid-Mediated Epigenetic Regulation Of Immune Functions, Jessica Margaret Sido
Cannabinoid-Mediated Epigenetic Regulation Of Immune Functions, Jessica Margaret Sido
Theses and Dissertations
The cannabinoid system consisting of exogenous and endogenous ligands as well as dedicated receptors has been proposed to play a regulatory role in immune functions. The exogenous cannabinoid Δ9-tetrahydrocannabinol (THC), one of the most widely studied marijuana derivatives, has been associated with multiple anti-inflammatory properties over the years. The majority of THC research has centered on the shift from Th1 to Th2 responses however, the complexity of inflammation has since increased. Recent studies have revealed that epigenome, Th cell subsets, and immunoregulatory cell induction, are all known to impact inflammation. In the current research, we have attempted to look holistically …
Characterization Of Stard4 And Stard6 Proteins In Human Ovarian Tissue And Human Granulosa Cells And Cloning Of Human Stard4 Transcripts, Aisha Shaaban
Theses and Dissertations
Progesterone is essential hormone for pregnancy, which is produced by the human corpus luteum in early pregnancy until the placenta assumes this function. Transport of the cholesterol from the outer to the inner mitochondrial membrane is the rate limiting step for the de novo synthesis of pregnenolone (the precursor to progesterone), a process mediated by STARD1. STARD1 contains a C-terminal lipid binding domain which binds cholesterol and an N-terminal domain targeting STARD1 to the mitochondrial membrane. Unlike STARD1, STARD4 and STARD6 proteins lack a mitochondrial targeting sequence; however, they can bind cholesterol and increase steroidogenesis in model systems. In this …
Goal Achievement In Young Adults With Asperger Syndrome And High Functioning Autism, Melissa Racobaldo
Goal Achievement In Young Adults With Asperger Syndrome And High Functioning Autism, Melissa Racobaldo
Theses and Dissertations
Purpose: This study aimed to evaluate perspectives of young adults with Asperger syndrome (AS) and High Functioning Autism (HFA) regarding supports and services, future goals, and confidence in their success. The goal of this study was to identify valuable supports and areas in which this support was lacking. Identifying areas of support for young adults with AS/HFA transitioning into adulthood aids in providing consistent services for successful goal achievement. The study has value among genetic counselors as the discovery of genetic etiologies of autism has led to referral of families with ASD to the genetics clinic. Methods: Young adults with …