Medicine and Health Sciences Commons^™

Week Of December 18, 2017, New York Medical College

InTouch

• Prominent Trauma Surgeon Addresses 14th Annual Louis R.M. DelGuercio Professorship and Research Day
• GSA Organizes Successful Second Annual Snowman Project
• SOM P2P Committee Recognizes Role Models at NYMC

Week Of December 11, 2017, New York Medical College

InTouch

• SOM Launches Bench-to-Bedside Seminar Series
• Student Services Announces New Positions

Week Of December 4, 2017, New York Medical College

InTouch

• NYMC Reflects at Museum of Jewish Heritage
• D.P.T. Class of 2019 Share Their Good Works at Community Service Presentations
• Department of Pediatrics and the Children's Health and Research Foundation Hosts Seventh Annual Assistant Professor Pediatric Research Symposium
• School of Medicine Alumni Celebrate at Reunion Weekend

Comparative Effectiveness And Safety Of Empagliflozin On Cardiovascular Mortality And Morbidity In Adults With Type 2 Diabetes, Wilbert S. Aronow, Tatyana Shamliyan

NYMC Faculty Publications

Background: Based on a single placebo-controlled randomized clinical trial, empagliflozin is licensed to reduce cardiovascular death in diabetes and comorbid cardiovascular disease. Methods: We examined the comparative effectiveness of empagliflozin on mortality and cardiovascular morbidity in type 2 diabetes. We conducted random-effects direct frequentist meta-analyses of aggregate data and appraised the quality of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. Our search in PubMed, EMBASE, the Cochrane Library, clinicaltrials.gov, and PharmaPendium up to May 2017 identified 11 meta-analyses, multiple publications, and unpublished data from 29 randomized controlled trials (RCTs). Results: Empagliflozin reduces all-cause mortality [relative …

Harmonizing Lipidomics: Nist Interlaboratory Comparison Exercise For Lipidomics Using Srm 1950-Metabolites In Frozen Human Plasma, J Bowden, C Ulmer, C Jones, J Koelmel, L Abdullah, Houli Jiang, Michal Schwartzman, Amaury Cazenave-Gassiot, Antonio Checa, Michelle Cinel, Romain Colas, Serge Cremers, Edward Dennis, James Evans, Alexander Fauland, Jun Han, Houli Jiang, Michal Schwartzman

NYMC Faculty Publications

As the lipidomics field continues to advance, self-evaluation within the community is critical. Here, we performed an interlaboratory comparison exercise for lipidomics using Standard Reference Material (SRM) 1950-Metabolites in Frozen Human Plasma, a commercially available reference material. The interlaboratory study comprised 31 diverse laboratories, with each laboratory using a different lipidomics workflow. A total of 1,527 unique lipids were measured across all laboratories and consensus location estimates and associated uncertainties were determined for 339 of these lipids measured at the sum composition level by five or more participating laboratories. These evaluated lipids detected in SRM 1950 serve as community-wide benchmarks …

Week Of November 20, 2017, New York Medical College

InTouch

• The Music of Mozart Comes Alive at Met
• StuHE Hosts Career Mentor Session
• SHSP Weighs In at APHA 2017
• NYMC Welcomes Human Rights Institute for Middle School Student Leaders to Campus

Week Of November 13, 2017, New York Medical College

InTouch

• Mark J. Kittleson, Ph.D., is Named Chair of the Department of Public Health in the School of Health Sciences and Practice
• Renowned Trauma Surgeon to Address 14th Annual Louis R.M. DelGuercio Professorship and Research Day
• NYMC Recognizes Alumnus for 18 Years of Micro Lectures
• M.P.H. Student Adds Global Experience to Public Health Education
• Dental Students Present on First-Ever Research Elective

Week Of November 6, 2017, New York Medical College

InTouch

• Gladys M. Ayala, M.D., M.P.H., is Named Interim Vice Dean for the School of Medicine
• NYMC Among Doctors of Distinction
• Touro College of Dental Medicine at New York Medical College Hosts Talk by Holocaust Survivor

Comparative Trial Between Neonatal Intensive Care Incubator, Neonatal Laminar Flow And Radiant Warmer, J Perez, F Perez, Sergio Golombek, Augusto Sola

NYMC Faculty Publications

No abstract provided.

Week Of October 30, 2017, New York Medical College

InTouch

• School of Medicine Class of 2021 Officially Dons White Coats for the First Time
• NYMC Reaches Out to Puerto Rico
• REDCap Comes to NYMC
• Health Sciences Library Celebrates Faculty Authorship
• Symposium Focuses on Tick-Borne Disease
• NYMC Goes Pink

Week Of October 23, 2017, New York Medical College

InTouch

• SHSP Hosts Special Dean's Lecture
• NYMC Ranks High in Low Student Loan Default Rates
• Department of Microbiology and Immunology Receives Generous Gift
• 19th Annual Race for Rehab Supports Achilles International
• Students Clubs Enrich Campus Life
• NYMC Has Heart
• D.P.T. Class of 2019 Celebrates National Physical Therapy Month

Week Of October 2, 2017, New York Medical College

InTouch

• NYMC Pride Shines at Founder's Dinner
• NYMC Receives $150,000 Grant from Hyundai Hope On Wheels
• NYMC Goes Gold for Childhood Cancer Awareness Month
• NYMC Expands Shomer Shabbos Residency Positions

Peptidyl-Prolyl Isomerase 1 Regulates Ca(2+) Handling By Modulating Sarco(Endo)Plasmic Reticulum Calcium Atpase And Na(2+)/Ca(2+) Exchanger 1 Protein Levels And Function, V Sacchi, B Wang, D Kubli, A Martinez, J Jin, R Alvarez, N Hariharan, C Glembotski, T Uchida, J Malter, Y Yang, P Gross, C Zhang, S Houser, Marcello Rota, M Sussman

NYMC Faculty Publications

BACKGROUND: Aberrant Ca(2+) handling is a prominent feature of heart failure. Elucidation of the molecular mechanisms responsible for aberrant Ca(2+) handling is essential for the development of strategies to blunt pathological changes in calcium dynamics. The peptidyl-prolyl cis-trans isomerase peptidyl-prolyl isomerase 1 (Pin1) is a critical mediator of myocardial hypertrophy development and cardiac progenitor cell cycle. However, the influence of Pin1 on calcium cycling regulation has not been explored. On the basis of these findings, the aim of this study is to define Pin1 as a novel modulator of Ca(2+) handling, with implications for improving myocardial contractility and potential for …

Complete Genome Sequence Of A Colistin-Resistant Escherichia Coli Strain Harboring Mcr-1 On An Inchi2 Plasmid In The United States, V Gilrane, S Lobo, Weihua Huang, J Zhuge, Changhong Yin, Donald Chen, K Alvarez, Alexandra Budhai, I Nadelman, Nevenka Dimitrova, John Fallon, Guiqing Wang

NYMC Faculty Publications

We report here the incidental detection and complete genome sequence of a urinary Escherichia coli strain harboring mcr-1 and resistant to colistin in a New York patient returning from Portugal in 2016. This strain, with sequence type 1485 (ST1485), was a non-extended-spectrum beta-lactamase (ESBL) and non-carbapenemase producer and carried the mcr-1 gene on an IncHI2 plasmid.

Week Of September 18, 2017, New York Medical College

InTouch

• Building the Touro College of Dental Medicine Clinical Training Facility − From the Inside Out
• Noted Physiotherapist Shares His Views on Cultural Competence
• Founder of Achilles International Gives Inspirational Talk

Drug-Induced Causes Of Secondary Hypertension, Wilbert S. Aronow

NYMC Faculty Publications

No abstract provided.

Week Of August 21, 2017, New York Medical College

InTouch

• Eduardo Lopez, M.D., is the Inaugural the Catherine and Ladislav P. Hinterbuchner Endowed Chair in Rehabilitation Medicine
• Sixth Annual STAR Student Research Forum Showcases Impressive Summer Investigative Works
• SHSP Students Join LEND at WIHD
• SHSP Hosts Special Public Health Practice Council Meeting

Week Of August 14, 2017, New York Medical College

InTouch

• The School of Medicine Class of 2021 Joins the College Community
• Center for Long-Term Care Welcomes Notable Physiotherapist and Philanthropist for Special Presentation
• GSBMS Welcomes New Students
• HSL Hosts Talk on the Health of the First President

The Global Alliance For Infections In Surgery: Defining A Model For Antimicrobial Stewardship-Results From An International Cross-Sectional Survey, M Sartelli, F Labricciosa, P Barbadoro, L Pagani, L Ansaloni, Rifat Latifi, N Shafiq, K Koike, I Kozlovska, A Kumar, L Lagunes, Rifat Latifi, J Lee, N Shafiq

NYMC Faculty Publications

BACKGROUND: Antimicrobial Stewardship Programs (ASPs) have been promoted to optimize antimicrobial usage and patient outcomes, and to reduce the emergence of antimicrobial-resistant organisms. However, the best strategies for an ASP are not definitively established and are likely to vary based on local culture, policy, and routine clinical practice, and probably limited resources in middle-income countries. The aim of this study is to evaluate structures and resources of antimicrobial stewardship teams (ASTs) in surgical departments from different regions of the world. METHODS: A cross-sectional web-based survey was conducted in 2016 on 173 physicians who participated in the AGORA (Antimicrobials: A Global …

Towards A Personalized Cancer Gene Therapy: A Case Of Clear Cell Renal Cell Carcinoma, Dumitru Iacobas, Sanda Iacobas

NYMC Faculty Publications

No abstract provided.

Week Of July 24, 2017, New York Medical College

InTouch

• The Catherine and Ladislav P. Hinterbuchner Endowed Chair in Rehabilitation Medicine Dedication Ceremony Is Set for August 10
• Touro Scholar Offers Online Archive Designed to Showcase Scholarship
• Touro College of Dental Medicine at New York Medical College Welcomes the Class of 2021

Week Of July 10, 2017, New York Medical College

InTouch

• Diane E. Heck, Ph.D., Is Appointed Associate Dean for Research in the School of Health Sciences and Practice
• Bridge and Seed Funding Grants Awarded
• Ronnie Myers, D.D.S., Is Named Dean of the Touro College of Dental Medicine at New York Medical College
• NYMC SOM and Touro Law Center Collaborate
• School of Medicine Office of Admissions Seeks Interviewers

Complete Versus Culprit Only Revascularization In St-Elevation Myocardial Infarction-A Perspective On Recent Trials And Recommendations, Gabriela Andries, Sahil Khera, Robert Timmermans, Wilbert Aronow

NYMC Faculty Publications

The presence of multivessel coronary artery disease (CAD) is strongly associated with higher 30-day mortality, reduced myocardial reperfusion success, reinfarction, and occurrence of major adverse cardiac events (MACE) at 1 year compared with single-vessel CAD. Despite higher morbidity and mortality in patients with ST-elevation myocardial infarction (STEMI) and coexistent multivessel CAD, major guidelines recommended against percutaneous coronary intervention (PCI) on non-culprit lesions at the time of primary PCI in patients with STEMI who are hemodynamically stable. The presence of multivessel CAD often poses a therapeutic dilemma for interventional cardiologists. A few larger scale randomized controlled trials (RCTs) and meta-analyses have …

Week Of June 26, 2017, New York Medical College

InTouch

• Professor Emeritus Catherine N. Hinterbuchner, M.D., Leaves Legacy of Endowed Professorship and Chair of the Department of Rehabilitation Medicine
• School of Medicine Hosts First Microbiome Translational Science Conference
• Department of Family and Community Medicine Hosts Annual Preceptor Appreciation Dinner
• School of Medicine Office of Admissions Seeks Interviewers
• SOM P2P Committee Recognizes Role Models at NYMC
• From the Collection of Edward C. Halperin, M.D., M.A.

Week Of June 12, 2017, New York Medical College

InTouch

• New York Medical College Marks its 158th Commencement Ceremony, Bestowing Degrees on 395 Graduates
• NYMC Unveils the Center of Excellence in Precision Medicine and Responses to Bioterrorism and Disasters
• Office of Medical Education Hosts Preceptor Appreciation Banquet
• SHSP Applauds New Honor Society Inductees
• TCDM Makes Progress on Dental Clinic

Week Of May 15, 2017, New York Medical College

InTouch

• Department of Family and Community Medicine Hosts Fifth Annual Research Day
• Warmer Weather and Campus Greenery Gets NYMC Moving

Week Of May 8, 2017, New York Medical College

InTouch

• Doctor of Physical Therapy Class of 2019 Celebrates and Reflects at White Coat Ceremony
• Lectureship Honors the Late Gabor Kaley, Ph.D.
• TCDM Hosts Pre-Dental Day
• Touro College of Dental Medicine Hosts ASDA/SPEA Event
• NYMC Collaborates for a Two-Week Global Bioethics Summer Program

Week Of May 1, 2017, New York Medical College

InTouch

• AOA Iota Chapter Celebrates Annual Lecture and Induction Banquet
• D.P.T. Class of 2017 Celebrates at Thirteenth Annual Doctoral Project Presentation Day
• NYMC Reflects on Yom Hashoah
• AMWA presents 2017 Gender Equity Faculty Award to Susan Rachlin, M.D.
• Turkeys Return to Campus

Evidence Of Strain Structure In Plasmodium Falciparum Var Gene Repertoires In Children From Gabon, West Africa, K Day, Y Artzy-Randrup, K Tiedje, V Rougeron, Donald S. Chen, T Rask, M Rorick, F Migot-Nabias, P Deloron, A Luty, M Pascual

NYMC Faculty Publications

Existing theory on competition for hosts between pathogen strains has proposed that immune selection can lead to the maintenance of strain structure consisting of discrete, weakly overlapping antigenic repertoires. This prediction of strain theory has conceptual overlap with fundamental ideas in ecology on niche partitioning and limiting similarity between coexisting species in an ecosystem, which oppose the hypothesis of neutral coexistence. For Plasmodium falciparum, strain theory has been specifically proposed in relation to the major surface antigen of the blood stage, known as PfEMP1 and encoded by the multicopy multigene family known as the var genes. Deep sampling of the …

The Transcriptional Regulation Of The Human Angiotensinogen Gene After High-Fat Diet Is Haplotype-Dependent: Novel Insights Into The Gene-Regulatory Networks And Implications For Human Hypertension, A Rana, S Jain, N Puri, M Kaw, N Sirianni, D Eren, Brahma Mopidevi, Anand Kumar

NYMC Faculty Publications

Single nucleotide polymorphisms (SNPs) in the human angiotensinogen (hAGT) gene may modulate its transcription and affect the regulation of blood pressure via activation of the renin-angiotensin aldosterone system (RAAS). In this regard, we have identified polymorphisms in the 2.5 Kb promoter of the hAGT gene that form two haplotype (Hap) blocks: -6A/G (-1670A/G, -1562C/T, -1561T/C) and -217A/G (-532T/C, -793A/G, -1074T/C & -1178G/A). hAGT gene with Hap -6A/-217A (Hap I) is associated with increased blood pressure whereas, Hap -6G/-217G (Hap II) is associated with normal blood pressure in human subjects. Since RAAS over activity contributes to hypertension in obesity, we have …