Open Access. Powered by Scholars. Published by Universities.®
- Keyword
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Biophotonics: Electrochemiluminescence At Microelectrodes During Pcr Amplification Of Dna, Rosemary L. Smith, Scott Collins
Biophotonics: Electrochemiluminescence At Microelectrodes During Pcr Amplification Of Dna, Rosemary L. Smith, Scott Collins
University of Maine Office of Research Administration: Grant Reports
This project investigates a new technique for in situ quantification of Polymerase Chain Reaction (PCR) amplification products using electrochemiluminescence (ECL). The technique implements the highly sensitive, ECL detection and quantification of tris(2,2'bipyridyl) ruthenium (II) labeled DNA. This method is expected to yield significant improvement in speed, cost and performance over existing quantitative PCR methods, by reducing the number and quantity of reagents, reducing the number of sample preparation steps, increasing sensitivity, and shortening analysis time.
Homocysteine, Folate, And Vitamins B6 And B12 Blood Levels In Relation To Cognitive Performance: The Maine-Syracuse Study, Merrill F. Elias, Michael A. Robbins, Marc M. Budge, Penelope K. Elias, Suzanne L. Brennan, Carole Johnston, Zsuzsanna Nagy, Christopher J. Bates
Homocysteine, Folate, And Vitamins B6 And B12 Blood Levels In Relation To Cognitive Performance: The Maine-Syracuse Study, Merrill F. Elias, Michael A. Robbins, Marc M. Budge, Penelope K. Elias, Suzanne L. Brennan, Carole Johnston, Zsuzsanna Nagy, Christopher J. Bates
Maine-Syracuse Longitudinal Papers
Objective: Our objective was to examine associations among plasma homocysteine concentrations (tHcy), the tHcy-cofactors (folate, vitamins B6 and B12), and multiple domains of cognitive performance, with statistical adjustment for possible confounds, including cardiovascular disease risk factors (CVD-RF) and cardiovascular disease (CVD). Methods: Subjects were 812 partici- pants (58% women) of the Maine-Syracuse study who were free of dementia and stroke. Employing a cross-sectional design and multiple regression analyses, fasting concentrations of tHcy and its vitamin cofactors (folate, B6, and B12) were related to multiple domains of cognitive performance. Results: With adjustment for age, education, gender, ethnicity, and the …