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Can The Hummingbird Sign Contribute To The Diagnosis Of Idiopathic Normal Pressure Hydrocephalus?, Hali̇l Önder, Selcuk Çomoğlu Jan 2022

Can The Hummingbird Sign Contribute To The Diagnosis Of Idiopathic Normal Pressure Hydrocephalus?, Hali̇l Önder, Selcuk Çomoğlu

Turkish Journal of Medical Sciences

To the Editor,


The Clinical Follow-Up And Management Of Covid-19 In Children And Adolescents Withan Immunocompromised State Or A Malignancy, İrem Ceren Erbaş, Hati̇ce Karaoğlu Asrak, Ayşe Çakil Güzi̇n, Şi̇lem Özdem Alataş, Şefi̇ka Akyol, Meral Torun Bayram, Refi̇k Emre Çeçen, Di̇lek İnce, Özlem Tüfekçi̇, Nurşen Belet Jan 2022

The Clinical Follow-Up And Management Of Covid-19 In Children And Adolescents Withan Immunocompromised State Or A Malignancy, İrem Ceren Erbaş, Hati̇ce Karaoğlu Asrak, Ayşe Çakil Güzi̇n, Şi̇lem Özdem Alataş, Şefi̇ka Akyol, Meral Torun Bayram, Refi̇k Emre Çeçen, Di̇lek İnce, Özlem Tüfekçi̇, Nurşen Belet

Turkish Journal of Medical Sciences

Background/aim: It is still not known how an immunosuppressive state affects the response to coronavirus disease 2019 (COVID-19) in children and adolescents. The aim of this study was to evaluate clinical characteristics, outcomes, and follow-up results of COVID-19 in pediatric patients with a history of immunocompromise or malignancy, retrospectively. Materials and methods: Patients with a diagnosis of COVID-19 who were under 18 years of age and had a history of immunosuppressive chronic disease or under immunosuppressant treatment were included in the study. Patients were applied to our outpatient clinic or consulted to our department in a tertiary center during the …


Optimal Screw Positioning In Cervical Pedicles To Avoid Complications, Kerem Atalar, Zafer Kutay Coşkun, Ahmet Memduh Kaymaz Jan 2022

Optimal Screw Positioning In Cervical Pedicles To Avoid Complications, Kerem Atalar, Zafer Kutay Coşkun, Ahmet Memduh Kaymaz

Turkish Journal of Medical Sciences

Background/aim: Cervical instability can be caused by a variety of factors, including trauma, tumors, or infection. The cervical transpedicular screw (CPS) is one of the most modern procedures for treating cervical instability. Despite the fact that numerous innovative techniques for CPS have been proposed, the appropriate screw entry points and screw directions have yet to be thoroughly established. The aim of this study is to determine the screw insertion angles and screw entry point distances based on reference points, pedicle axis lengths, and pedicle axis intersections for each vertebra from cervical (C) C2 to C7 in both right and left …


Arthroscopic Bankart Repair Improves Upper Limb Exercise Capacity, Shoulder Function And Quality Of Life, Fi̇gen Dağ, Fehmi̇ Volkan Öztuna, Di̇dem Deri̇ci̇ Yildirim, Özlem Bölgen Çi̇men Jan 2022

Arthroscopic Bankart Repair Improves Upper Limb Exercise Capacity, Shoulder Function And Quality Of Life, Fi̇gen Dağ, Fehmi̇ Volkan Öztuna, Di̇dem Deri̇ci̇ Yildirim, Özlem Bölgen Çi̇men

Turkish Journal of Medical Sciences

No abstract provided.


The Relationship Between Ethmoidal Foramina And Orbital Fat Herniation, Fati̇h Çankal, Mustafa Kaya, İbrahi̇m Tekdemi̇r Jan 2022

The Relationship Between Ethmoidal Foramina And Orbital Fat Herniation, Fati̇h Çankal, Mustafa Kaya, İbrahi̇m Tekdemi̇r

Turkish Journal of Medical Sciences

Background/aim: The aims of this study are to determine the incidence and more frequent localizations of orbital fat tissue herniation accompanying dehiscences in the medial orbital wall and to investigate the relationship between orbital fat tissue herniations and the anterior and posterior ethmoidal foramina. Material and methods: One thousand two hundred patients who had undergone computed tomography with a preliminary diagnosis of sinusitis and who had no previous facial, orbital, paranasal sinus surgeries or history of trauma were retrospectively analyzed. The localization of the ethmoidal foramina and orbital fat tissue herniations were marked. In patients with orbital fat tissue herniation, …


Evaluation Of The Frequency And Intensity Of Covid-19 In Patients With Ankylosingspondylitis Under Anti-Tnf Therapy, Sümeyye Merve Türk, Zeynep Öztürk, Damla Karataş, Ünal Erkorkmaz, Emel Gönüllü Jan 2022

Evaluation Of The Frequency And Intensity Of Covid-19 In Patients With Ankylosingspondylitis Under Anti-Tnf Therapy, Sümeyye Merve Türk, Zeynep Öztürk, Damla Karataş, Ünal Erkorkmaz, Emel Gönüllü

Turkish Journal of Medical Sciences

No abstract provided.


An Evaluation Of The Results Of Convalescent Plasma Therapy Applied To Pregnant Womendiagnosed As Covid-19- Positive In A Pandemic Center: A Prospective Cohort Study, Seyi̇t Ahmet Erol, Atakan Tanaçan, Hakan Apaydin, Şule Göncü Ayhan, Deni̇z Oluklu, Derya Uyan Hendem, Serpi̇l Ünlü, Abdulsamet Erden, Özlem Moraloğlu Teki̇n, Ahmet Omma, İhsan Ateş, Orhan Küçükşahi̇n, Di̇lek Şahi̇n Jan 2022

An Evaluation Of The Results Of Convalescent Plasma Therapy Applied To Pregnant Womendiagnosed As Covid-19- Positive In A Pandemic Center: A Prospective Cohort Study, Seyi̇t Ahmet Erol, Atakan Tanaçan, Hakan Apaydin, Şule Göncü Ayhan, Deni̇z Oluklu, Derya Uyan Hendem, Serpi̇l Ünlü, Abdulsamet Erden, Özlem Moraloğlu Teki̇n, Ahmet Omma, İhsan Ateş, Orhan Küçükşahi̇n, Di̇lek Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: Convalescent plasma (CP) might be an additional treatment modality in COVID-19. The aim of this study was to compare CP-related clinical characteristics and perinatal outcomes in pregnant women with mild or moderate-severe COVID-19. Materials and methods: This prospective cohort study included 36 pregnant women (12 mild and 24 moderate-severe), who underwent CP therapy. The CP obtained from recently recovered donors was transfused to patients together with maximum supportive care and antiviral agents. The groups were then compared in respect of clinical characteristics, laboratory parameters, obstetric complications, and neonatal outcomes. Results: Significant differences were determined between the groups in respect …


Morphometric Analysis Of Hippocampus And Intracranial Formations Based On Their Stages In Patients Diagnosed With Major Cognitive Disorder, Nurullah Yücel, Muzaffer Şeker, Mehmet Tuğrul Yilmaz, Zaki̇r Sakci, Yaşar Bükte Jan 2022

Morphometric Analysis Of Hippocampus And Intracranial Formations Based On Their Stages In Patients Diagnosed With Major Cognitive Disorder, Nurullah Yücel, Muzaffer Şeker, Mehmet Tuğrul Yilmaz, Zaki̇r Sakci, Yaşar Bükte

Turkish Journal of Medical Sciences

No abstract provided.


Analgesic Efficacy Of Ultrasound Guided Unilateral Erector Spinae Plane Block For Laparoscopic Inguinal Hernia Repair: A Randomized Controlled Study, Savaş Altinsoy, Derya Özkan, Fatma Kavak Akelma, Jüli̇de Ergi̇l Jan 2022

Analgesic Efficacy Of Ultrasound Guided Unilateral Erector Spinae Plane Block For Laparoscopic Inguinal Hernia Repair: A Randomized Controlled Study, Savaş Altinsoy, Derya Özkan, Fatma Kavak Akelma, Jüli̇de Ergi̇l

Turkish Journal of Medical Sciences

No abstract provided.


Mortality Related Factors On Hypoxic Ischemic Encephalopathic Patients Treated With Therapeutic Hypothermia: A 11-Year Single Center Experience, Mehmet Fati̇h Deveci̇, Hati̇ce Turgut, Meral Alagöz, Hüseyi̇n Kaya, İsmai̇l Kürşad Gökçe, Ramazan Özdemi̇r Jan 2022

Mortality Related Factors On Hypoxic Ischemic Encephalopathic Patients Treated With Therapeutic Hypothermia: A 11-Year Single Center Experience, Mehmet Fati̇h Deveci̇, Hati̇ce Turgut, Meral Alagöz, Hüseyi̇n Kaya, İsmai̇l Kürşad Gökçe, Ramazan Özdemi̇r

Turkish Journal of Medical Sciences

No abstract provided.


Remdesivir Treatment For Patients With Moderate To Severe Covid-19, İmran Hasanoğlu, Hati̇ce Rahmet Güner, İlhami̇ Çeli̇k, Fi̇kret Kanat, Ayşe Batirel, Gülçi̇n Telli̇ Di̇zman, Esma Eryilmaz Eren, Di̇lek Yildiz Sevgi̇, İlkay Bozkurt, Kadri̇ye Kart Yaşar, Sevtap Şenoğlu, Esra Kazak, Ridvan Karaali̇, Aysel Kocagül Çeli̇kbaş, Hüsnü Pullukçu Jan 2022

Remdesivir Treatment For Patients With Moderate To Severe Covid-19, İmran Hasanoğlu, Hati̇ce Rahmet Güner, İlhami̇ Çeli̇k, Fi̇kret Kanat, Ayşe Batirel, Gülçi̇n Telli̇ Di̇zman, Esma Eryilmaz Eren, Di̇lek Yildiz Sevgi̇, İlkay Bozkurt, Kadri̇ye Kart Yaşar, Sevtap Şenoğlu, Esra Kazak, Ridvan Karaali̇, Aysel Kocagül Çeli̇kbaş, Hüsnü Pullukçu

Turkish Journal of Medical Sciences

Background/aim: Remdesivir, which was first developed for the treatment of Ebola disease but failed to meet expectations, has become hope in the fight against the COVID-19 pandemic. This study aimed to evaluate risk factors for mortality and prognosis of adult moderate/severe COVID-19 patients treated with remdesivir, and safety and tolerability of 5 days of remdesivir treatment. Materials and methods: This multicenter prospective observational study was conducted in 14 centers in Turkey. Pregnancy or breastfeeding, multiorgan failure, or usage of vasopressors for septic shock, ALT > 5 × the upper limit of the normal range, or eGRF


The Role Of Cd8+ Regulatory T Cells And B Cell Subsets In Patients With Covid-19, Hülya Uçaryilmaz, Di̇lek Ergün, Hüsametti̇n Vatansev, Hande Köksal, Onur Ural, Uğur Arslan, Hasi̇be Artaç Jan 2022

The Role Of Cd8+ Regulatory T Cells And B Cell Subsets In Patients With Covid-19, Hülya Uçaryilmaz, Di̇lek Ergün, Hüsametti̇n Vatansev, Hande Köksal, Onur Ural, Uğur Arslan, Hasi̇be Artaç

Turkish Journal of Medical Sciences

Background/aim: Coronavirus disease 2019 (COVID-19) has a wide clinical spectrum from asymptomatic to mild, moderate, and severe cases. There are still many unknowns about the role of immunoregulatory mechanisms in COVID-19. We aimed to study regulatory T cells (Tregs) and B cell subsets and evaluate their correlations with severity of COVID-19. Materials and methods: In total, 50 patients with COVID-19 confirmed by PCR (mean age = 49.9 ± 12.8 years) and 40 healthy control (mean age = 47.9 ± 14.7 years) were included in this study. The patients were classified as 14 mild (median age = 35.5 [24-73] years), 22 …


Use Of Ultrasonography In Confirming The Malposition Of The I-Gel In Pediatric Patients: A Prospective Observational Study, Faruk Çi̇çekci̇, Mehmet Selçuk Uluer, Mehmet Sargin, Emi̇ne Aslanlar, İnci̇ Kara, Muslu Kazim Körez Jan 2022

Use Of Ultrasonography In Confirming The Malposition Of The I-Gel In Pediatric Patients: A Prospective Observational Study, Faruk Çi̇çekci̇, Mehmet Selçuk Uluer, Mehmet Sargin, Emi̇ne Aslanlar, İnci̇ Kara, Muslu Kazim Körez

Turkish Journal of Medical Sciences

Background/aim: This study was designed to observe and compare the performance of fiberoptic laryngeal (FOL) view, leakage test (LT) and ultrasonography (USG) usage in detecting i-gel position in pediatric patients. Materials and methods: One hundred ten consecutive children were included in this single-armed prospective observational study. After anesthetic induction, i-gel placement confirmed using FOL and LT was evaluated using USG in three planes. According to our scoring system, acceptable and unacceptable grades (FOL, LT and USG) were determined to describe placement. Sensitivity and specificity were determined by comparing USG performance with the other two tests. Results: Ultrasonography was found a …


Effect Of Perioperative Factors On The Prognosis Of Patients With Hepatocellular Carcinoma Who Underwent Hepatectomy, Lining Xu, Yingying Xu, Guiping Li, Bo Yang Jan 2022

Effect Of Perioperative Factors On The Prognosis Of Patients With Hepatocellular Carcinoma Who Underwent Hepatectomy, Lining Xu, Yingying Xu, Guiping Li, Bo Yang

Turkish Journal of Medical Sciences

Background/aim: Hepatic resection is a potentially curative treatment for patients with hepatocellular carcinoma (HCC). Controversy persists regarding preoperative and intraoperative characteristics related to patient survival in various medical institutes. This study aimed to evaluate the impact of preoperative and intraoperative factors on the long-term survival of patients with HCC who underwent hepatectomy. Materials and methods: Data on 455 patients with HCC who underwent hepatectomy over a 20-year period were retrospectively reviewed. Univariate and multivariate Cox regression analyses were performed for preoperative- and intraoperative-related prognostic factors. Results: The 1-, 3-, 5-, and 10-year overall survival rates of patients with HCC who …


Evaluation Of Cardiovascular Changes In Patients With Gastric Wall Fat Halo Sign, Ali̇ Küpeli̇, Eser Bulut, Edhem Ünver, Gürkan Danişan Jan 2022

Evaluation Of Cardiovascular Changes In Patients With Gastric Wall Fat Halo Sign, Ali̇ Küpeli̇, Eser Bulut, Edhem Ünver, Gürkan Danişan

Turkish Journal of Medical Sciences

Background/aim: This study aims to investigate the relationship between gastric wall fat halo sign and potentially associated cardiovascular disease (CVD) in thoracic computed tomography (CT). Materials and methods: Between October 2020 and January 2021, 62 patients with gastric wall fat halo sign and 62 controls were evaluated with thorax CT. Patient's height, weight, body mass index (BMI), sex, age, comorbidities, laboratory parameters, diameters of cardiac axes, aorta and pulmonary artery; aorta and coronary artery calcium scores were recorded for the two groups. Results: No significant differences were found in sex, age, height, body weight or BMI between the two groups …


Correlations Between Glycosylated Hemoglobin And Glucose Levels In Chinese Older Adults With Newly Diagnosed Type 2 Diabetes Mellitus, Yun Yu, Jun Yang, Wei Tang Jan 2022

Correlations Between Glycosylated Hemoglobin And Glucose Levels In Chinese Older Adults With Newly Diagnosed Type 2 Diabetes Mellitus, Yun Yu, Jun Yang, Wei Tang

Turkish Journal of Medical Sciences

Background/aim: To explore the correlations between glycosylated hemoglobin (HbA1c) and glucose levels in older adults with newly diagnosed type 2 diabetes mellitus (T2DM). Materials and methods: A total of 783 participants aged ≥60 years were enrolled. The 75-g oral glucose tolerance test (OGTT) was conducted and HbA1c was measured. The participants were divided into normal glucose tolerance (NGT)HbA1c, Pre-DMHbA1c, and T2DMHbA1c groups based on the HbA1c diagnostic criteria. The correlations between HbA1c and glucose levels of the OGTT were analyzed. Results: When HbA1c ≥ 6.5% in older people, HbA1c was positively correlated with Glucose 0 min and 120 min of …


Future Pandemics: How Can We Be Ready?, Zeynep Türe Yüce, Emi̇ne Alp Meşe Jan 2022

Future Pandemics: How Can We Be Ready?, Zeynep Türe Yüce, Emi̇ne Alp Meşe

Turkish Journal of Medical Sciences

No abstract provided.


Highlights In The Association Of Fragmented Qrs With Myocardial Fibrosis, Mehmet Eyüboğlu Jan 2022

Highlights In The Association Of Fragmented Qrs With Myocardial Fibrosis, Mehmet Eyüboğlu

Turkish Journal of Medical Sciences

No abstract provided.


Concordance Of Vestibular Test Batteries In Patients With Vestibular Neuritis, Burak Kabi̇ş, Hakan Tutar, Emre Gürses, Bülent Gündüz, Songül Aksoy Jan 2022

Concordance Of Vestibular Test Batteries In Patients With Vestibular Neuritis, Burak Kabi̇ş, Hakan Tutar, Emre Gürses, Bülent Gündüz, Songül Aksoy

Turkish Journal of Medical Sciences

Background/aim: A growing number of vestibular function tests are utilized to differentiate and verify the diagnosis of vestibular neuritis. The aim of this study is to retrospectively investigate the consistency of the results of the objective vestibular test batteries in patients with a preliminary diagnosis of vestibular neuritis. Materials and methods: We reviewed a total of 37 adult patients (mean age: 39.03 ± 11.67, 19 females, 18 males) who met the inclusion criteria with a prediagnosis of vestibular neuritis from 379 patients suffering vestibular symptoms. Caloric test (CVT), video head impulse test (vHIT), and ocular and cervical VEMP tests were …


The Respiratory Manifestations In Patients With Primary Sjögren?S Syndrome: Is Interstitial Lung Disease Related To Disease Activity?, Özlem Özdemi̇r Işik, Ayten Yazici, Ayşe Çefle Jan 2022

The Respiratory Manifestations In Patients With Primary Sjögren?S Syndrome: Is Interstitial Lung Disease Related To Disease Activity?, Özlem Özdemi̇r Işik, Ayten Yazici, Ayşe Çefle

Turkish Journal of Medical Sciences

Background/aim: Sjögren?s syndrome is a systemic, autoimmune disease and can affect many organs and systems. In this study, we aimed to evaluate the respiratory manifestations, and the association between interstitial lung disease (ILD) and disease activity in primary SS (pSS) patients. Materials and methods: The study design was retrospective cross-sectional, and 151 patients followed up with a diagnosis of pSS between 2004 and 2019 were included in the study. Demographic and clinical data, laboratory results, chest radiographs and thorax computed tomography (CT) results were obtained from patient files and hospital imaging system. Thorax CT was requested from all patients with …


Outcome Of Solid And Cavitary Pulmonary Nodules In Rheumatoid Arthritis Patients? Case Series, Aysun Aksoy, Derya Kocakaya, Yasemi̇n Yalçinkaya, Emi̇ne Bozkurtlar, Sai̇t Karakurt, Semi̇ha Emel Eryüksel, Güzi̇de Nevsun İnanç Jan 2022

Outcome Of Solid And Cavitary Pulmonary Nodules In Rheumatoid Arthritis Patients? Case Series, Aysun Aksoy, Derya Kocakaya, Yasemi̇n Yalçinkaya, Emi̇ne Bozkurtlar, Sai̇t Karakurt, Semi̇ha Emel Eryüksel, Güzi̇de Nevsun İnanç

Turkish Journal of Medical Sciences

Background/aim: Rheumatoid pulmonary nodule can be detected in up to 32% of rheumatoid arthritis (RA) patients and approximately one-third of nodules may cavitate. We aimed to evaluate characteristics of patients with RA developing cavitary pulmonary nodular (CPN) lesions under disease-modifying antirheumatic drugs (DMARDs), follow-up of both cavitary and solid nodules, and their outcome with the treatment. Materials and methods: RA patients who presented with CPN lesions during follow-up were recruited retrospectively in this case series analysis. Total numbers and mean diameters of cavitary and solid nodules in each thorax computed tomography (CT) have been determined and followed up by two …


Can Surfactants Affect Mortality And Morbidity In Term Infants With Respiratory Failure?, Senem Alkan Özdemi̇r, Özlem Yilman, Şebnem Çalkavur, Tüli̇n Gökmen Yildirim Jan 2022

Can Surfactants Affect Mortality And Morbidity In Term Infants With Respiratory Failure?, Senem Alkan Özdemi̇r, Özlem Yilman, Şebnem Çalkavur, Tüli̇n Gökmen Yildirim

Turkish Journal of Medical Sciences

Background/aim: We aimed to discuss term infants who are given surfactant due to respiratory disorder according to the underlying etiology, the dose of surfactant administration, and the need for repeated surfactant administration. Materials and methods: In this retrospective study infants hospitalized in the 4th level neonatal intensive care unit during January 2019 and December 2021 and administered surfactant due to respiratory distress were included. Term infants given surfactant due to respiratory failure were included in the study through the data recording system. The number of surfactant doses, indications for administration, mortality, duration of hospitalization, intubation time, and inotrope use were …


Enhancing Effect Of Nicotine On Electrical Field Stimulation Elicited Contractile Responses In Isolated Rabbit Bladder Straight Muscle; The Role Of Cannabinoid And Vanilloid Receptors, Sevi̇l Özger İlhan, Gökçe Sevi̇m Öztürk Fi̇ncan, Yağmur Okçay, Derya Sebi̇le Koç, Celi̇l İlker Aşkin, Ayşe Kübra Ki̇bar, İsmai̇l Mert Vural, Yusuf Sarioğlu Jan 2022

Enhancing Effect Of Nicotine On Electrical Field Stimulation Elicited Contractile Responses In Isolated Rabbit Bladder Straight Muscle; The Role Of Cannabinoid And Vanilloid Receptors, Sevi̇l Özger İlhan, Gökçe Sevi̇m Öztürk Fi̇ncan, Yağmur Okçay, Derya Sebi̇le Koç, Celi̇l İlker Aşkin, Ayşe Kübra Ki̇bar, İsmai̇l Mert Vural, Yusuf Sarioğlu

Turkish Journal of Medical Sciences

Background/aim: Nicotine acts as an agonist of nicotinic acetylcholine receptors (nAChR). These receptors belong to a superfamily of ligand-gated ion channels. We previously demonstrated that nicotine increased electrical field stimulation (EFS)-induced contractile or relaxation responses, possibly by facilitating neurotransmitter release from nerve terminals in various rabbit tissues. Studies have shown that there is an interaction between the endocannabinoid and nicotinic systems. This study aimed to investigate the interaction between nicotine and the endocannabinoid system in the rabbit urine bladder and also investigate the enhancing effect of nicotine on EFS-induced contractile responses in rabbit isolated bladder smooth muscle and its interaction …


Low Handgrip Strength Is Associated With Diabetic Foot Disease In Geriatric Patients With Type 2 Diabetes, Eren İmre, Neşe Koçakgöl, Erdi̇ İmre Jan 2022

Low Handgrip Strength Is Associated With Diabetic Foot Disease In Geriatric Patients With Type 2 Diabetes, Eren İmre, Neşe Koçakgöl, Erdi̇ İmre

Turkish Journal of Medical Sciences

Background/aim: This study aims to reveal the prevalence of low handgrip strength in older patients with type 2 diabetes who have diabetic foot disease and to assess the association of handgrip strength with diabetic foot disease in older patients with type 2 diabetes. Materials and methods: Eighty-nine geriatric patients with diabetic foot ulcers and 69 patients without diabetic foot ulcers who presented to the endocrinology outpatient clinic between August 2020 and November 2021 were included in the study. The exclusion criteria were the usage of steroids, stroke-induced quadriplegia, myopathy, disability, hemodialysis treatment, type 1 diabetes, patients under 65 years of …


Clinicoradiological Evaluation Of Oxidative Stress Activity In Acute Cerebral Infarction In The First 24 H And The Qualitative Importance Of Dysfunctional Hdl In Stroke, Esra Demi̇r Ünal, Gönül Vural, Funda Eren, Sali̇m Neşeli̇oğlu, Özcan Erel Jan 2022

Clinicoradiological Evaluation Of Oxidative Stress Activity In Acute Cerebral Infarction In The First 24 H And The Qualitative Importance Of Dysfunctional Hdl In Stroke, Esra Demi̇r Ünal, Gönül Vural, Funda Eren, Sali̇m Neşeli̇oğlu, Özcan Erel

Turkish Journal of Medical Sciences

Background/aim: Acute cerebral infarction (ACI) occurs as a result of instant disruption of vascular flow that causes disbalance between oxidative/antioxidative activity. We examined the relationship of serum neuro-oxidative stress parameters with stroke severity and infarct volume in ACI and emphasized the qualitative importance of high-density lipoprotein (HDL) on its relationship with myeloperoxidase (MPO) and paraoxonase-1 (PON1) in the acute period of stroke. Materials and methods: One hundred ACI patients applied within the first 24 h and 50 healthy volunteers were included. The patient group was evaluated with demographic data (including arrival serum biochemical assessment), clinical disability scores, infarct volume, serum …


Central Vein Sign: Comparison Of Multiple Sclerosis And Leukoaraiosis, Hüseyi̇n Gökhan Yavaş, Ergi̇n Sağtaş Jan 2022

Central Vein Sign: Comparison Of Multiple Sclerosis And Leukoaraiosis, Hüseyi̇n Gökhan Yavaş, Ergi̇n Sağtaş

Turkish Journal of Medical Sciences

Background/aim: Leukoaraiosis produces white matter lesions (WML) similar to multiple sclerosis (MS) on brain magnetic resonance imaging (MRI), and the distinction between these two conditions is difficult radiologically. This study aimed to investigate the role of the central vein sign (CVS) in susceptibility-weighted imaging (SWI) sequence in distinguishing MS lesions from leukoaraiosis lesions in Turkish population. Materials and methods: In this prospective study, axial SWI and sagittal three-dimensional fluid-attenuated inversion recovery (3DFLAIR) were obtained in 374 consecutive patients. The study consisted of 169 (89 MS patients, 80 patients with leukoaraiosis) patients according to the inclusion and exclusion criteria. Two observers …


Endocarditis-Tr: Diagnosis, Treatment, And Prognosis Of The Infective Endocarditispatients Admitting Tertiary Centres Of Turkey, Ali̇ Nazmi̇ Çalik, Fatma Özlem Arican Özlük, Mehmet Baran Karataş, Yi̇ği̇t Çanga, Semi̇h Eren, Görkem Ayhan, Ayşe Sünbül, Ali̇ Pali̇ce, Aytaç Candemi̇r, Şükrü Akyüz, Mehdi̇ Zoghi̇, Ömer Kozan Jan 2022

Endocarditis-Tr: Diagnosis, Treatment, And Prognosis Of The Infective Endocarditispatients Admitting Tertiary Centres Of Turkey, Ali̇ Nazmi̇ Çalik, Fatma Özlem Arican Özlük, Mehmet Baran Karataş, Yi̇ği̇t Çanga, Semi̇h Eren, Görkem Ayhan, Ayşe Sünbül, Ali̇ Pali̇ce, Aytaç Candemi̇r, Şükrü Akyüz, Mehdi̇ Zoghi̇, Ömer Kozan

Turkish Journal of Medical Sciences

Background/aim: Infective endocarditis (IE) is still a significant cause of morbidity and mortality among cardiovascular diseases. ENDOCARDITIS-TR study aims to evaluate the compliance of the diagnostic and therapeutic methods being used in Turkey with current guidelines. Materials and methods: The ENDOCARDITIS-TR trial is a multicentre, prospective, observational study consisting of patients admitted to tertiary centres with a definite diagnose of IE. In addition to the demographic, clinical, microbiological, and echocardiographic findings of the patients, adverse events, indications for surgery, and in-hospital mortality were recorded during a 2-year time interval. Results: A total of 208 IE patients from 7 tertiary centres …


Investigation Of Mirna And Cytokine Expressions In Latent Tuberculosis Infection And Active Tuberculosis, Cengi̇z Çavuşoğlu, Muhsi̇n Özgür Çoğulu, Asude Durmaz, Zehra Cengi̇si̇z, Fethi̇ye Ferda Yilmaz, Mehmet Sezai̇ Taşbakan, Meltem Taşbakan, Cumhur Gündüz, Can Bi̇çmen, Onur Karaman, Hasan Taşlidere, Haluk Akin, Tülay Akarca, Mustafa Şevket Dereli̇ Jan 2022

Investigation Of Mirna And Cytokine Expressions In Latent Tuberculosis Infection And Active Tuberculosis, Cengi̇z Çavuşoğlu, Muhsi̇n Özgür Çoğulu, Asude Durmaz, Zehra Cengi̇si̇z, Fethi̇ye Ferda Yilmaz, Mehmet Sezai̇ Taşbakan, Meltem Taşbakan, Cumhur Gündüz, Can Bi̇çmen, Onur Karaman, Hasan Taşlidere, Haluk Akin, Tülay Akarca, Mustafa Şevket Dereli̇

Turkish Journal of Medical Sciences

No abstract provided.


Hydroxychloroquine Induces Endothelium-Dependent And Endothelium-Independent Relaxation Of Rat Aorta, Seyfullah Oktay Arslan, Muhammed Fati̇h Doğan, Sali̇ha Ayşenur Çam, Ibraheem Akram Omar, Fatma Uysal, Ali̇ Parlar, Ahmet Cenk Andaç, Oğuzhan Yildiz Jan 2022

Hydroxychloroquine Induces Endothelium-Dependent And Endothelium-Independent Relaxation Of Rat Aorta, Seyfullah Oktay Arslan, Muhammed Fati̇h Doğan, Sali̇ha Ayşenur Çam, Ibraheem Akram Omar, Fatma Uysal, Ali̇ Parlar, Ahmet Cenk Andaç, Oğuzhan Yildiz

Turkish Journal of Medical Sciences

No abstract provided.


Evaluation Of The Relationship Between Vitamin D Level And Adropin, Il-1ss, Il-6, And Oxidative Status In Women, Mehmet Zorlu, Abdüsselam Şekerci̇, Muhammed Tunç, Eray Meti̇n Güler, Bedi̇a Gülen, Cumali̇ Karatoprak, Muharrem Kiskaç, Mustafa Çakirca Jan 2022

Evaluation Of The Relationship Between Vitamin D Level And Adropin, Il-1ss, Il-6, And Oxidative Status In Women, Mehmet Zorlu, Abdüsselam Şekerci̇, Muhammed Tunç, Eray Meti̇n Güler, Bedi̇a Gülen, Cumali̇ Karatoprak, Muharrem Kiskaç, Mustafa Çakirca

Turkish Journal of Medical Sciences

Background/aim: Vitamin D, adropin, proinflammatory cytokines, and oxidative stress closely related with metabolic homeostasis and endothelial dysfunction. The aim of the present study is to investigate how vitamin D levels affect serum adropin, IL-1ß, IL-6, and oxidative stress. Materials and methods: A total of 77 female subjects were divided into 3 groups according to vitamin D levels. Biochemical parameters, adropin, IL-1ß, IL-6, oxidative stress markers were studied in these groups, and the results were compared statistically. Results: Serum adropin, IL-1ß, IL-6, total oxidant status (TOS) and total antioxidant status (TAS) and oxidative stress index (OSI) levels differed significantly between the …