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Articles 1 - 30 of 267
Full-Text Articles in Medicine and Health Sciences
Comparison Of Direct Laryngoscope And Mcgrath Videolaryngoscope In Terms Of Glottic View And Hemodynamics In Bariatric Surgery, Mehmet Çakir, Erhan Özyurt
Comparison Of Direct Laryngoscope And Mcgrath Videolaryngoscope In Terms Of Glottic View And Hemodynamics In Bariatric Surgery, Mehmet Çakir, Erhan Özyurt
Turkish Journal of Medical Sciences
Background/aim: In the recent years, videolaryngoscopes (VL) have emerged as alternative devices to direct laryngoscopes (DL) in difficult intubation situations. Therefore, we aimed to compare the Macintosh DL and McGrath VL in terms of the glottic image quality, intubation success, intubation time, hemodynamic response after intubation, and complications in bariatric surgery patients.Material and methods: After obtaining approval by the ethics committee and receiving informed consent, we recorded the demographic and physical data of patients undergoing bariatric surgery. Patients were divided into 2 groups: Group M was intubated with the Macintosh DL, and Group V was intubated with the McGrath VL. …
Comment On `Treatment Of Idiopathic Granulomatous Mastitis And Factors Related Withdisease Recurrence?, Emre Tekgöz, Seda Çolak, Muhammet Çinar, Sedat Yilmaz
Comment On `Treatment Of Idiopathic Granulomatous Mastitis And Factors Related Withdisease Recurrence?, Emre Tekgöz, Seda Çolak, Muhammet Çinar, Sedat Yilmaz
Turkish Journal of Medical Sciences
No abstract provided.
The Surgical Outcomes Of Trans-Scaphoid Perilunate Fracture-Dislocations, Cemal Kural, Bülent Tanriverdi̇, Ersi̇n Erçi̇n, Emre Baca, Murat Yilmaz
The Surgical Outcomes Of Trans-Scaphoid Perilunate Fracture-Dislocations, Cemal Kural, Bülent Tanriverdi̇, Ersi̇n Erçi̇n, Emre Baca, Murat Yilmaz
Turkish Journal of Medical Sciences
Background/aim: Trans-scaphoid perilunate fracture-dislocation (TSPFD) is a rare injury. TSPFD is a fracture-dislocation that severely disrupts the anatomical structure of the carpal bones and may occur as a result of a high energy trauma of the wrist or a fall on an open hand. In this study, the aim is to provide midterm clinical and radiological evaluations of cases diagnosed and treated as TSPFD.Materials and methods: Eleven patients diagnosed with TSPFD as a result of wrist trauma were treated surgically and were analysed retrospectively. Clinical and radiological follow-up of the cases was evaluated. The mean age of the patients was …
Clinical And Demographic Characteristics Of Children And Adolescents With Acute Vertigosymptoms: A Cross-Sectional Study, Arzu Yilmaz, Sema Ni̇lay Abseyi̇
Clinical And Demographic Characteristics Of Children And Adolescents With Acute Vertigosymptoms: A Cross-Sectional Study, Arzu Yilmaz, Sema Ni̇lay Abseyi̇
Turkish Journal of Medical Sciences
Background/aim: Vertigo is one of the rarely diagnosed disorders during childhood due to insufficient description of the children regarding their experiences to the physicians. The clinical features of children and adolescents admitted by acute vertigo symptoms were investigated to elaborate the subject retrospectively. Materials and methods: Between January 2017-July 2019, records of cases admitted with acute vertigo complaints to pediatric neurology were retrospectively examined. Results: Of 761 patients, mean age was 13.8 years, 64% (n = 487) were women, 22.6% (n = 172) of which were children (1-11 years). A total of 37.3% of the cases (n = 284) had …
Twenty Children With Non-Wilms Renal Tumors From A Reference Center In Central Anatolia, Turkey, Ekrem Ünal, Ebru Yilmaz, Alper Özcan, Bi̇lgen Işik, Musa Karakükcü, Cüneyt Turan, Hülya Akgün, Fi̇gen Öztürk, Abdulhaki̇m Coşkun, Mehmet Aki̇f Özdemi̇r, Türkan Patiroğlu
Twenty Children With Non-Wilms Renal Tumors From A Reference Center In Central Anatolia, Turkey, Ekrem Ünal, Ebru Yilmaz, Alper Özcan, Bi̇lgen Işik, Musa Karakükcü, Cüneyt Turan, Hülya Akgün, Fi̇gen Öztürk, Abdulhaki̇m Coşkun, Mehmet Aki̇f Özdemi̇r, Türkan Patiroğlu
Turkish Journal of Medical Sciences
Background/aim: Non-Wilms renal tumors (NWRTs) are rarely encountered in children. The aim of this study is to determine the treatment strategies, prognosis, outcomes, and survival of children with NWRTs at Erciyes University in Kayseri, Turkey.Materials and methods: Medical records of all patients (n = 20) treated for NWRTs over a 23-year period (1995-2018) were reviewed retrospectively.Results: There was male predominance (female/male: 7/13); the median age at diagnosis was 3.2 years old (0.1-13.5 years old). The major histological groups included mesoblastic nephroma (MBN), (n: 5, 25%), malignant rhabdoid tumor (MRT), (n: 5, 25%), renal cell carcinoma, (n: 3, 15%), inflammatory myofibroblastic …
Results Of Genicular Nerve Ablation By Radiofrequency In Osteoarthritis-Related Chronic Refractory Knee Pain, Zafer Yasi̇n Konya, Suna Akin Takmaz, Hülya Başar, Bülent Baltaci, Gülçi̇n Babaoğlu
Results Of Genicular Nerve Ablation By Radiofrequency In Osteoarthritis-Related Chronic Refractory Knee Pain, Zafer Yasi̇n Konya, Suna Akin Takmaz, Hülya Başar, Bülent Baltaci, Gülçi̇n Babaoğlu
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the medium- to long-term effects of radiofrequency (RF) ablation of genicular nerves for chronic refractory knee pain due to osteoarthritis (OA).Materials and methods: Forty-eight patients who underwent RF ablation of the genicular nerves were evaluated retrospectively. The visual analogue scale (VAS) score, Western Ontario and McMaster universities osteoarthritis index (WOMAC index), opioid and nonsteroidal antiinflammatory drug (NSAID) use score, quality of life score, and treatment satisfaction score were examined at 1, 3, and 6 months after the procedure.Results: The mean VAS scores were significantly lower at the 1-, 3-, and 6-month …
Cytomorphological Findings In Diagnosis Of Warthin Tumor, Fatma Fulya Köybaşioğlu, Bi̇nnur Önal, Ünsal Han, Ayşegül Adabağ, Ahmet Şahpaz
Cytomorphological Findings In Diagnosis Of Warthin Tumor, Fatma Fulya Köybaşioğlu, Bi̇nnur Önal, Ünsal Han, Ayşegül Adabağ, Ahmet Şahpaz
Turkish Journal of Medical Sciences
Background/aim: To define the cytomorphologic findings leading to difficulties in diagnosis of Warthin tumors (WTs).Materials and methods: Forty-eight histopathologically diagnosed WT patients who had fine needle aspiration cytology preoperatively were reevaluated for defining the presence or absence of lymphocytes, oncocytic cell layer, oncocytic cell papillae, granular debris background, mucoid background, macrophages, polymorphonuclear cells, mast cells, squamous-like cells, atypical vacuolated cytoplasmic cells, and giant cells.Results: Forty-seven tumors were in the parotid gland and one in the submandibular gland. There were 37 (77%) male and 11 (23%) female patients. Cytopathologically in 36 patients the diagnosis was benign neoplasm (WT); in 6, other …
Avascular Necrosis Less Frequently Found In Systemic Lupus Erythematosus Patients With The Use Of Alternate Day Corticosteroid, İsmai̇l Doğan, Umut Kalyoncu, Levent Kiliç, Ali̇ Akdoğan, Ömer Karadağ, Sedat Ki̇raz, Şazi̇ye Şule Apraş Bi̇lgen, Ali̇ İhsan Ertenli̇
Avascular Necrosis Less Frequently Found In Systemic Lupus Erythematosus Patients With The Use Of Alternate Day Corticosteroid, İsmai̇l Doğan, Umut Kalyoncu, Levent Kiliç, Ali̇ Akdoğan, Ömer Karadağ, Sedat Ki̇raz, Şazi̇ye Şule Apraş Bi̇lgen, Ali̇ İhsan Ertenli̇
Turkish Journal of Medical Sciences
Background/aim: Avascular necrosis (AVN) is the death of bone due to compromise of blood flow. The etiology of AVN is multifactorial; corticosteroid usage is the second most significant factor after trauma, and systemic lupus erythematosus (SLE) is the most common underlying disease. The objective of this study was to assess the factors of AVN in SLE patients. Materials and methods: The study included 127 patients with SLE who fulfilled 1997 American College of Rheumatology (ACR) revised criteria. Demographic data, age at SLE diagnosis, disease duration, disease activity, body mass index, clinical findings, antiphospholipid syndrome, steroid usage, dose and duration, comorbid …
An Evaluation Of The Effects Of Caffeic Acid Phenethyl Ester And Ankaferd Blood Stopper On Secondary Wound Healing Of Oral Mucosal Tissue, Mehmet Gül, Ahmet Günay, Abdulsamet Tanik
An Evaluation Of The Effects Of Caffeic Acid Phenethyl Ester And Ankaferd Blood Stopper On Secondary Wound Healing Of Oral Mucosal Tissue, Mehmet Gül, Ahmet Günay, Abdulsamet Tanik
Turkish Journal of Medical Sciences
Background/aim: Caffeic acid phenethyl ester (CAPE) and Ankaferd Blood Stopper (ABS) are considered to contribute to wound healing. The purpose of this study was to investigate the effect of ABS and CAPE on secondary wound healing of oral mucosal tissue. Materials and methods: In total, 63 male Sprague-Dawley rats were used in this study. The animals were randomly divided into three groups and anaesthetized with ketamine (8 mg/100 g, intraperitoneally): a control group, CAPE group, and ABS group. A full-thickness excisional wound was created using a 4 mm punch biopsy tool. Topical ABS and CAPE were then applied in each …
Geoepidemiology And Clinical Characteristics Of Neonatal Lupus Erythematosus: Asystematic Literature Review Of Individual Patients' Data, Abdulsamet Erden, Antonis Fanouri̇aki̇s, Levent Kiliç, Alper Sari, Berkan Armağan, Emre Bi̇lgi̇n, Yusuf Zi̇ya Şener, Benazi̇r Hymabaccus, Fati̇h Gürler, Serdar Ceylan, Sedat Ki̇raz, Ömer Karadağ, Dimitrious Boumpas
Geoepidemiology And Clinical Characteristics Of Neonatal Lupus Erythematosus: Asystematic Literature Review Of Individual Patients' Data, Abdulsamet Erden, Antonis Fanouri̇aki̇s, Levent Kiliç, Alper Sari, Berkan Armağan, Emre Bi̇lgi̇n, Yusuf Zi̇ya Şener, Benazi̇r Hymabaccus, Fati̇h Gürler, Serdar Ceylan, Sedat Ki̇raz, Ömer Karadağ, Dimitrious Boumpas
Turkish Journal of Medical Sciences
Background/aim: Neonatal lupus erythematosus (NLE) is an autoimmune syndrome caused by transplacental transmission of maternal autoantibodies, often with devastating consequences. The objective of this systematic literature review was to analyze the demographic data, geoepidemiology, clinical, and serological characteristics associated with NLE. Materials and methods: We performed a systematic literature search of the Pubmed database covering the period from 1976 to August 2015, using the MeSH terms "neonatal lupus" or "congenital heart block". To be included in the study, articles of any type (original articles, case series, and case reports) had to report on infants with NLE on an individualized (i.e. …
Different Perspectives Of Immunizations During Pregnancy, Gökce Celep, Aysu Duyan Çamurdan, Fatma Nur Baran Aksakal, Osman Fadil Kara
Different Perspectives Of Immunizations During Pregnancy, Gökce Celep, Aysu Duyan Çamurdan, Fatma Nur Baran Aksakal, Osman Fadil Kara
Turkish Journal of Medical Sciences
Background/aim: Pregnant women and infants are at risk of severe lower respiratory tract infections induced by influenza or pertussis. The uptake of both vaccines is poor in spite of proven benefits and safety. We aimed to determine the knowledge and attitude of pregnant women and their primary healthcare providers towards immunization during pregnancy. Materials and methods: This cross-sectional and interventional study was conducted in northern Turkey in 2016. It had 3 different groups including 786 pregnant women, 146 primary healthcare staff, and 97 family practitioners. Different questionnaires were filled by each group. The intervention phase of the study consisted of …
Correlation Of Serum Fatty Acid Binding Protein-4 And Interleukin-6 With Airflowlimitation And Quality Of Life In Stable And Acute Exacerbation Of Copd, Mohammad Reza Aslani, Zeynab Ghazaei, Hassan Ghobadi
Correlation Of Serum Fatty Acid Binding Protein-4 And Interleukin-6 With Airflowlimitation And Quality Of Life In Stable And Acute Exacerbation Of Copd, Mohammad Reza Aslani, Zeynab Ghazaei, Hassan Ghobadi
Turkish Journal of Medical Sciences
Background/aim: The serum fatty acid binding protein 4 (FABP-4) level increases in chronic inflammatory diseases. The present study aimed to examine serum FABP-4 and interleukin (IL)-6 levels in patients with stable and acute exacerbation of chronic obstructive pulmonary disease (COPD) and the correlation of these markers with airflow limitation. Materials and methods: We measured serum FABP-4 and IL-6 levels in 60 COPD patients [30 stable COPD (SCOPD), and 30 acute exacerbation of COPD (AECOPD)], and 30 healthy subjects and compared them with airflow limitation according to the COPD stage in the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) criteria, …
Effect Of Sevoflurane Anaesthesia On Nasal Mask In Endoscopic Retrogradecholangiopancreatography: Is It A Preferred Alternative?, Bülent Baltaci, Hülya Başar, Murat Keki̇lli̇, Mert Naki̇p, Fati̇h Karaahmet, Mehmet Çakirca, Meli̇s Engi̇n, Meltem Bektaş
Effect Of Sevoflurane Anaesthesia On Nasal Mask In Endoscopic Retrogradecholangiopancreatography: Is It A Preferred Alternative?, Bülent Baltaci, Hülya Başar, Murat Keki̇lli̇, Mert Naki̇p, Fati̇h Karaahmet, Mehmet Çakirca, Meli̇s Engi̇n, Meltem Bektaş
Turkish Journal of Medical Sciences
Background/aim: Endoscopic retrograde cholangiopancreatography (ERCP) often requires deep sedation. Propofol provides adequate sedation and amnesia at subhypnotic doses, but safe guarding the patient's airway is important for preventing respiratory depression or hypoxic events. This study compared sedation levels, operator satisfaction, intraoperative and recovery characteristics using sevoflurane with nasal mask and propofol in ERCP. Material and methods: Sixty-one patients underwent ERCP (Group I: propofol, n = 31; Group II, sevoflurane, n = 30), with sedation controlled by the Ramsay sedation scale (RSS). The patients' demographic data, procedure length, overall drug dose, hemodynamic changes, duration of recovery and Aldrete scores during recovery …
The In Vitro Cytotoxic, Genotoxic, And Oxidative Damage Potentials Of The Oral Artificialsweetener Aspartame On Cultured Human Blood Cells, Kenan Çadirci, Özlem Özdemi̇r Tozlu, Hasan Türkez, Adi̇l Mardi̇noğlu
The In Vitro Cytotoxic, Genotoxic, And Oxidative Damage Potentials Of The Oral Artificialsweetener Aspartame On Cultured Human Blood Cells, Kenan Çadirci, Özlem Özdemi̇r Tozlu, Hasan Türkez, Adi̇l Mardi̇noğlu
Turkish Journal of Medical Sciences
Background/aim: Aspartame (APM, L-aspartyl-L-phenylalanine methylester) is a low-calorie, nonsaccharide artificial sweetener widely used in foods and beverages. When metabolized by the body, APM is broken down into aspartic acid, phenylalanine amino acids, and a third substance, methanol. Since the amino acid phenylalanine serves as a neurotransmitter building block affecting the brain, and methanol is converted into toxic formaldehyde, APM has deleterious effects on the body and brain. Thus, its safety and, toxicity have been the subjects of concern ever since it was first discovered. Although many studies have been performed on it, due to the presence of conflicting data in …
Thiol/Disulphide Homeostasis In Intensive Care Unit Patients With Sepsis And Septic Shock, Hami̇t Yildiz
Thiol/Disulphide Homeostasis In Intensive Care Unit Patients With Sepsis And Septic Shock, Hami̇t Yildiz
Turkish Journal of Medical Sciences
Background/aim: Sepsis is a condition caused by infection followed by unregulated inflammatory response which may lead to organ dysfunction. The aim of this study is to be the first in the literature and it has been designed to show the thiol/disulphide changes in patients with sepsis and septic shock and their correlation with acute phase reactants. Material and methods: A total of 113 patients (septic shock 53 and sepsis 60) and 60 healthy control subjects have been enrolled in this study from the period February 2018 to 2019. The patients were divided in 2 groups: nonsurvivors (74) and survivors (39). …
Reliability And Validity Of The Turkish Version Of The Vocal Fatigue Index, Seher Şi̇ri̇n, Mehmet Fati̇h Öğüt, Cem Bi̇lgen
Reliability And Validity Of The Turkish Version Of The Vocal Fatigue Index, Seher Şi̇ri̇n, Mehmet Fati̇h Öğüt, Cem Bi̇lgen
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to evaluate the reliability and validity of the Turkish version of the Vocal Fatigue Index (VFI). Materials and methods: The study was conducted with 535 participants including 285 patients with voice disorders and 250 healthy controls. Internal consistency and test-retest reliability were calculated for the reliability analysis. The mean VFI factor scores of both groups were compared. The strength and direction of the relation between VFI and Voice-Related Quality of Life (V-RQOL) measure was evaluated for the validity analysis. Results: The Cronbach's alpha coefficient of VFI factor scores was found to be 0.920 …
Ocular Toxicity Of Intravitreal Golimumab In A Rabbit Model, Ceren Durmaz Engi̇n, Serap Ci̇laker Miçili, Osman Yilmaz, Hüsnü Alper Bağriyanik, Beki̇r Uğur Ergür, Fatoş Önen, Ali̇ Osman Saatci̇
Ocular Toxicity Of Intravitreal Golimumab In A Rabbit Model, Ceren Durmaz Engi̇n, Serap Ci̇laker Miçili, Osman Yilmaz, Hüsnü Alper Bağriyanik, Beki̇r Uğur Ergür, Fatoş Önen, Ali̇ Osman Saatci̇
Turkish Journal of Medical Sciences
Background/aim: To investigate the effect of intravitreal golimumab on rabbit retina histopathology. Materials and methods: Sixteen albino New Zealand rabbits were divided into three groups. The right eye of each rabbit in groups I, II, and III received a single intravitreal injection of 5 mg/0.05 mL (6 eyes), 10 mg/0.1 mL (6 eyes), or 20 mg/0.2 mL (4 eyes) golimumab, while left eyes served as controls with the same volume of a balanced salt solution injection. All animals were examined using slit-lamp biomicroscopy and indirect ophthalmoscopy before and after intravitreal injection and at days 1 and 7. Animals were euthanized …
Baicalein Nanofiber Scaffold Containing Hyaluronic Acid And Polyvinyl Alcohol: Preparation And Evaluation, Kamel Bachimam, Ezgi̇ Emül, Necdet Sağlam, Feza Korkusuz
Baicalein Nanofiber Scaffold Containing Hyaluronic Acid And Polyvinyl Alcohol: Preparation And Evaluation, Kamel Bachimam, Ezgi̇ Emül, Necdet Sağlam, Feza Korkusuz
Turkish Journal of Medical Sciences
Background/aim: Bone tumor is one of the major causes of tissue bone loss, particularly after performing surgical excision operation to bone lesion that needs to be replaced by biomaterials and ensure a complete filling of tissue-loss spaces. The purpose of our study was to produce a nanofiber-based bone graft scaffold to fill the gaps resulted from bone cancer treatment and also capable of carrying functional molecules that can play a major role in preventing further cancer growth at the targeted bone tissue. Materials and methods: Electrospinning method was used in order to produce nanofibers from different kinds of polymers; Hyaluronic …
Melatonin, Aging, And Covid-19: Could Melatonin Be Beneficial For Covid-19 Treatment In The Elderly?, Güler Öztürk, Kazi̇me Gonca Akbulut, Şevi̇n Güney
Melatonin, Aging, And Covid-19: Could Melatonin Be Beneficial For Covid-19 Treatment In The Elderly?, Güler Öztürk, Kazi̇me Gonca Akbulut, Şevi̇n Güney
Turkish Journal of Medical Sciences
The aim of this review is to summarize current studies on the relationship between melatonin and aging. Nowadays, age-related diseases come into prominence, and identifying age-related changes and developing proper therapeutic approaches are counted as some of the major issues regarding community health. Melatonin is the main hormone of the pineal gland. Melatonin is known to influence many biological processes in the body, including circadian rhythms, the immune system, and neuroendocrine and cardiovascular functions. Melatonin rhythms also reflect the biological process of aging. Aging is an extremely complex and multifactorial process. Melatonin levels decline considerably with aging and its decline …
Urinay Neutrophil Gelatinase-Associated Lipocalin As A Biomarker In Different Renal Problems, Di̇dem Turgut, Serhan Vahi̇t Pi̇şki̇npaşa, Ezgi̇ Çoşkun Yeni̇gün, Ni̇hal Aydemi̇r, Fati̇h Dede
Urinay Neutrophil Gelatinase-Associated Lipocalin As A Biomarker In Different Renal Problems, Di̇dem Turgut, Serhan Vahi̇t Pi̇şki̇npaşa, Ezgi̇ Çoşkun Yeni̇gün, Ni̇hal Aydemi̇r, Fati̇h Dede
Turkish Journal of Medical Sciences
Background/aim: Neutrophil gelatinase-associated lipocalin (NGAL) is used previously to estimate the etiology, severity, and clinical outcomes of acute kidney injury (AKI). However, the role of urinary NGAL (uNGAL) in the postrenal setting is not clear. In our study, we aimed to discover the cut-off value of uNGAL that can be used in the differential diagnosis of underlying AKI etiologies. Materials and methods: In this prospective cross-sectional study, we examined 82 subjects in four groups: patients that had (1) postrenal AKI; (2) AKI other than postrenal etiologies; (3) stable chronic kidney disease; and (4) healthy subjects. A renal function assessment was …
The Importance Of Quality And Accreditation In Health Care Services In The Process Ofstruggle Against Covid-19, Demet Gökmen Kavak, Ayşe Si̇bel Öksüz, Canan Cengi̇z, İbrahi̇m Hali̇l Kayral, Fi̇gen Çi̇zmeci̇ Şenel
The Importance Of Quality And Accreditation In Health Care Services In The Process Ofstruggle Against Covid-19, Demet Gökmen Kavak, Ayşe Si̇bel Öksüz, Canan Cengi̇z, İbrahi̇m Hali̇l Kayral, Fi̇gen Çi̇zmeci̇ Şenel
Turkish Journal of Medical Sciences
Background/aim: The aim of this research is to evaluate the relationship between the quality of health and accreditation standards with the Covid-19 process and to reveal the importance of quality and accreditation in health care in the process of combating coronavirus. Materials and methods: The relationship between hospital accreditation standards of Turkish Healthcare Quality and Accreditation Institute and the Covid-19 process was evaluated. The standards were analyzed within the framework of the technical guidance areas provided by the World Health Organization for countries for the Covid-19 process. Results: The standards were found to be 79,6% related to the Covid-19 process. …
Influence Of Aluminum Salts On Covid-19 Infected Patients, Ali̇ Demi̇r, İbrahi̇m Erayman, Oğuz Doğan, Murat Keki̇lli̇
Influence Of Aluminum Salts On Covid-19 Infected Patients, Ali̇ Demi̇r, İbrahi̇m Erayman, Oğuz Doğan, Murat Keki̇lli̇
Turkish Journal of Medical Sciences
Background/aim: Based on the antiviral and antibacterial properties of aluminum salts, we aimed to find out the influence of aluminum salts on COVID-19 infected patients. Materials and methods: We performed an observational retrospective cohort study which includes the patients diagnosed as COVID-19 and received aluminum salts in addition to actual treatments during hospitalization as the treatment group (Alum Group). Patients who received standard COVID-19 treatment protocols in the Infectious Diseases Clinics were included as the Control Group. Clinical findings, laboratory parameters, length of stay, survival, radiological follow-up, intensive care and mechanical ventilation needs, the presence of comorbidity, polymerase chain reaction …
A Single Center Cohort Of 40 Severe Covid-19 Patients Who Were Treated Withconvalescent Plasma, Ali̇i̇hsan Gemi̇ci̇, Hülya Bi̇lgen, Cem Erdoğan, Abdullah Kansu, Oktay Olmuşçeli̇k, Hüseyi̇n Saffet Beköz, Rumeysa Çakmak, Ali̇ Mert, Ömür Gökmen Sevi̇ndi̇k
A Single Center Cohort Of 40 Severe Covid-19 Patients Who Were Treated Withconvalescent Plasma, Ali̇i̇hsan Gemi̇ci̇, Hülya Bi̇lgen, Cem Erdoğan, Abdullah Kansu, Oktay Olmuşçeli̇k, Hüseyi̇n Saffet Beköz, Rumeysa Çakmak, Ali̇ Mert, Ömür Gökmen Sevi̇ndi̇k
Turkish Journal of Medical Sciences
Background/aim: A SARS-Cov2 infection which was first arised from Wuhan in December 2019 and named as COVID-19. Still there lacks either a specific treatment or a vaccine to treat COVID-19. Convalescent plasma (CP) was previously used successfully to treat SARS-CoV-1 and MERS infections. Health authority in Turkey has published a guideline to integrate this promising option in the treatment process of patients who are prone to high risk of developing severe COVID 19. Materials and Methods: Forty consecutive patients who had received CP at our center were included in the study. Demographics, COVID-19 specific parameters, biomarkers to detect the severity …
The Assessment Of The Serum Levels Of Tweak And Prostaglandin F2∝ In Covid - 19, Demet Yalçin Kehri̇bar, Mustafa Ci̇hangi̇roğlu, Emi̇ne Sehmen, Bahatti̇n Avci, Mustafa Çapraz, Maruf Boran, Caner Günaydin, Meti̇n Özgen
The Assessment Of The Serum Levels Of Tweak And Prostaglandin F2∝ In Covid - 19, Demet Yalçin Kehri̇bar, Mustafa Ci̇hangi̇roğlu, Emi̇ne Sehmen, Bahatti̇n Avci, Mustafa Çapraz, Maruf Boran, Caner Günaydin, Meti̇n Özgen
Turkish Journal of Medical Sciences
Background/aim: It is claimed that aberrant immune response has a more important role than the cytopathic effect of the virus in the morbidity and mortality of the coronavirus disease 2019 (COVID-19). We aimed to investigate the possible roles of tumor necrosis factor-like weak inducer of apoptosis (TWEAK)/Fn14 pathway and leukotrienes (LT) in uncontrolled immune response that occurs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Materials and methods: This study included 25 asymptomatic patients and 35 patients with lung involvement who were diagnosed with COVID-19 as well as 22 healthy volunteers. Lung involvement was determined using computed-tomography. Serum TWEAK, LTE4, …
Proteomic Analysis Of The Anticancer Effect Of Various Extracts Of Endemicthermopsis Turcica In Human Cervical Cancer Cells, Mustafa Yildiz, Hakan Terzi̇, Sali̇ha Handan Yildiz, Nuray Varol, Müjgan Özdemi̇r Erdoğan, Murat Kasap, Nermi̇n Akçali, Mustafa Solak
Proteomic Analysis Of The Anticancer Effect Of Various Extracts Of Endemicthermopsis Turcica In Human Cervical Cancer Cells, Mustafa Yildiz, Hakan Terzi̇, Sali̇ha Handan Yildiz, Nuray Varol, Müjgan Özdemi̇r Erdoğan, Murat Kasap, Nermi̇n Akçali, Mustafa Solak
Turkish Journal of Medical Sciences
Background/aim: Thermopsis turcica is a perennial species endemic to Turkey and different extracts of T. turcica have an antiproliferative effect on cancer cells, but there has not been any report on HeLa (human cervical cancer) cells. Materials and methods: To get a better understanding of the molecular mechanism of anticancer activity of methanolic extracts of leaves (LE) and flowers (FE) of T. turcica, we employed 2-DE-based proteomics to explore the proteins involved in anticancer activity in HeLa cells. Results: T. turcica extracts showed a potent cytotoxic effect on HeLa cells with the IC50 values of 1.75 mg/mL for LE and …
Comparison Of The Sensititre Yeastone Antifungal Method With The Clsi M27-A3reference Method To Determine The Activity Of Antifungal Agents Against Clinical Isolatesof Candida Spp., Rabi̇ye Altinbaş, Ayşe Bariş, Sümeyye Şen, Recep Öztürk, Nuri̇ Ki̇raz
Comparison Of The Sensititre Yeastone Antifungal Method With The Clsi M27-A3reference Method To Determine The Activity Of Antifungal Agents Against Clinical Isolatesof Candida Spp., Rabi̇ye Altinbaş, Ayşe Bariş, Sümeyye Şen, Recep Öztürk, Nuri̇ Ki̇raz
Turkish Journal of Medical Sciences
Background and aim: Infections caused by Candida species are significantly increasing today, and invasive Candida infections are generally associated with high mortality. Early diagnosis and identification of Candida spp. is important for the determination of antifungal agents that will be used for treatment. The aim of the present study was to provide a better regimen for Candida infections in the future. Materials and methods: The Sensititre YeastOne (SYO) method was compared with The Clinical Laboratory Standards Institute (CLSI) reference broth microdilution (BMD) testing method. Endpoints of minimal inhibitory concentrations (MICs) were determined for both methods. Results: By using both methods, …
Mango Ginger (Curcuma Amada) Inhibits Collagen-Induced Arthritis By Modulatinginflammatory Cytokine Levels In Rats, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Nurhan Şahi̇n, İbrahi̇m Hani̇fi̇ Özercan, Süleyman Serdar Koca, Vijaya Juturu, Kazi̇m Şahi̇n
Mango Ginger (Curcuma Amada) Inhibits Collagen-Induced Arthritis By Modulatinginflammatory Cytokine Levels In Rats, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Nurhan Şahi̇n, İbrahi̇m Hani̇fi̇ Özercan, Süleyman Serdar Koca, Vijaya Juturu, Kazi̇m Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: Mango ginger (MG: curcuma amada) has antioxidant and antiinflammatory activities. The aim was to evaluate the antiarthritic potential efficacy of MG on collagen-induced arthritis. Materials and methods: Twenty-one female Wistar-albino rats were divided into three groups. Arthritis was induced by intradermal injections of type II collagen and Freund's adjuvant. MG extract was orally administered starting from the first collagen injection. TNF-α, IL-6, IL-17, obestatin, sclerostin, and DKK-1 serum levels were determined, and perisynovial inflammation and cartilage-bone destruction in the paws were histologically evaluated. Moreover, joint tissue TNF-α, IL-17, NF-κB, and COX-2 levels were analyzed. Results: TNF-α, IL-17, IL-6, and …
In Reply: Comparing Performance Of Mcgrath Mac Videolaryngoscope In Morbidlyobese And Nonobese, Zehra İpek Arslan Aydin
In Reply: Comparing Performance Of Mcgrath Mac Videolaryngoscope In Morbidlyobese And Nonobese, Zehra İpek Arslan Aydin
Turkish Journal of Medical Sciences
No abstract provided.
Understanding Dynamics Of Pandemics, Levent Akin, Mustafa Gökhan Gözel
Understanding Dynamics Of Pandemics, Levent Akin, Mustafa Gökhan Gözel
Turkish Journal of Medical Sciences
Along the centuries, novel strain of virus such as influenza produces pandemics which increase illness, death and disruption in the countries. Spanish flu in 1918, Asian flu in 1957, Hong Kong flu in 1968 and swine flu in 2009 were known pandemic which had various characteristics in terms of morbidity and mortality. A current pandemic is caused by novel corona virus originated from China. COVID-19 pandemic is very similar to Spanish, Hong Kong, Asian and swine influenza pandemics in terms of spreading to world by the mobilized people. Burden of pandemic is considered in terms of disease transmissibility and the …
The Early Impact Of The Covid-19 Pandemic On The Global And Turkish Economy, Ömer Açikgöz, Asli Günay
The Early Impact Of The Covid-19 Pandemic On The Global And Turkish Economy, Ömer Açikgöz, Asli Günay
Turkish Journal of Medical Sciences
Background/aim: Individuals infected by the Covid-19 potentially are at risk of health and economic well-being. Today, the Covid-19 is a global issue, and the world economy can be interpreted as almost at the standstill. In this context, this study aims to discuss the potential first reactions of short and long term global economic impacts of the pandemic through sectors by assessing its costs according to the data announced for both the world and Turkey. In addition, this study tries to put forth possible economic and political scenarios for the post-pandemic world. Materials and methods: This is a review article that …