Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Treatment (4)
- Oxidative stress (3)
- Antioxidant enzymes (2)
- Asthma (2)
- Bone mineral density (2)
-
- Children (2)
- Dexmedetomidine (2)
- Diabetes mellitus (2)
- HPLC (2)
- Homocysteine (2)
- Lipid peroxidation (2)
- Malondialdehyde (2)
- Placenta (2)
- Prevalence (2)
- Prognosis (2)
- Questionnaire (2)
- Shigella flexneri (2)
- Sigmoid volvulus (2)
- Violence (2)
- AIDS (1)
- Abuse (1)
- Acetylsalicylic acid (1)
- Acinetobacter (1)
- Acute appendicitis (1)
- Acute brucellosis (1)
- Acute eosinophilic pneumonia (1)
- Acute exacerbation (1)
- Acute pancreatitis (1)
- Acute phase reactants (1)
- Adenosine deaminase (1)
Articles 1 - 30 of 105
Full-Text Articles in Medicine and Health Sciences
Resident Physicians In Turkey: Results Of A Survey Of 1069 Residents From 11 Provinces, Erhan Aysan, Gürol Köroğlu, Vi̇ldan Türkeli̇, Abdullah Özgönül, Ali̇ Özyaşar, Çağri Gülümser, Kemal Kiliç, Türker Ertürk, Özhan Özdemi̇r, Ahmet Hamdi̇ Alpaslan, Savaş Bayrak
Resident Physicians In Turkey: Results Of A Survey Of 1069 Residents From 11 Provinces, Erhan Aysan, Gürol Köroğlu, Vi̇ldan Türkeli̇, Abdullah Özgönül, Ali̇ Özyaşar, Çağri Gülümser, Kemal Kiliç, Türker Ertürk, Özhan Özdemi̇r, Ahmet Hamdi̇ Alpaslan, Savaş Bayrak
Turkish Journal of Medical Sciences
Aims: To determine the problems, expectations and objectives of resident physicians in Turkey and to provide a contribution to the development and amendment of the residency program. Background: Residency varies considerably in accordance with factors like teaching staff, the institution and government policies. If characteristics, problems, expectations and objectives of resident physicians are stated and known, development and amendment of residency programs will be both easier and faster. Materials and Methods: A 50-question survey was completed by a randomly selected 1069 resident physicians from 15 university and 12 teaching hospitals in 11 provinces (İstanbul-503, Ankara-116, İzmir-86, Erzurum-71, Sivas-60, Bolu-49, Bursa-49, …
Il-10 And Il-13 Production By Peripheral Blood Mononuclear Cells In Patients With Diabetes Mellitus, Ali̇ İnal, Uğur Muşabak, Göksal Keski̇n, Levent Özsari, Ali̇ Şengül, Mustafa Kutlu, Çağatay Öktenli̇, Zeki̇ Yeşi̇lova
Il-10 And Il-13 Production By Peripheral Blood Mononuclear Cells In Patients With Diabetes Mellitus, Ali̇ İnal, Uğur Muşabak, Göksal Keski̇n, Levent Özsari, Ali̇ Şengül, Mustafa Kutlu, Çağatay Öktenli̇, Zeki̇ Yeşi̇lova
Turkish Journal of Medical Sciences
Aim: It is generally accepted that proinflammatory cytokines secreted by mononuclear cells are responsible for pancreatic beta (B) cell destruction in animal models of autoimmune type-1 diabetes mellitus (DM). Several studies have shown that markers of inflammation and pro-inflammatory cytokines such as interleukin (IL)-10 and IL-13 associate with the metabolic syndrome, dyslipidemia, type-2 DM and type-1 DM. The aim of this study was to examine the in vitro production of IL-10 and IL-13 in cultures of peripheral lymphocytes obtained from patients with type-2 DM, type-1 DM and healthy controls. Materials and Methods: Twenty patients (10 females, 10 males) with type-2 …
Efficacy Of Clomipramine, Sertraline And Terazosin Treatments In Premature Ejaculation, Altuğ Tuncel, Yilmaz Aslan, M. Murad Başar, Ali̇ Atan
Efficacy Of Clomipramine, Sertraline And Terazosin Treatments In Premature Ejaculation, Altuğ Tuncel, Yilmaz Aslan, M. Murad Başar, Ali̇ Atan
Turkish Journal of Medical Sciences
Aim: To compare the efficacy of oral clomipramine, sertraline and terazosin to placebo in premature ejaculation. Materials and Methods: A total of 90 patients aged from 20 to 58 years were enrolled in this study. Patients were randomized into 4 groups. Group 1 (n: 22) took placebo and served as controls. Group 2 (n: 23) patients took 25 mg clomipramine HCl nightly; Group 3 (n: 20) 50 mg sertraline nightly; and Group 4 (n: 25) 5 mg terazosin nightly. The medications were used for two months. After 8 sexual attempts, the patients' clinical responses were assessed using the patient self-description …
Rare Complication Of Meckel´S Diverticulum: Loop Formation Of Diverticulum, Oğuzhan Karatepe, Cem Dural, Candaş Erçeti̇n, Gamze Çitlak, Artur Salmaslioğlu, Osman Bi̇lgi̇n Gülçi̇çek, Servet Karahan
Rare Complication Of Meckel´S Diverticulum: Loop Formation Of Diverticulum, Oğuzhan Karatepe, Cem Dural, Candaş Erçeti̇n, Gamze Çitlak, Artur Salmaslioğlu, Osman Bi̇lgi̇n Gülçi̇çek, Servet Karahan
Turkish Journal of Medical Sciences
Meckel's diverticulum is the most prevalent congenital anomaly of the gastrointestinal tract, and is reported to occur in 1%-3% of the general population and autopsy series. The total lifetime rate of complications is widely accepted at 4%. Intestinal obstruction is the most common complication in adult patients. We present the diagnosis and management of our patient with intestinal obstruction due to loop formations of a Meckel's diverticulum.
Adhesion Of Beta1 Integrin To Fibronectin Regulates Cam-Dr Phenotype Via P21^{Waf1/Cip1} In Hl60 Acute Myeloid Leukemia (Aml) Cells, Hande Canpinar, Güneş Esendağli, Emi̇n Kansu, Aysen Günel Özcan, Di̇cle Güç
Adhesion Of Beta1 Integrin To Fibronectin Regulates Cam-Dr Phenotype Via P21^{Waf1/Cip1} In Hl60 Acute Myeloid Leukemia (Aml) Cells, Hande Canpinar, Güneş Esendağli, Emi̇n Kansu, Aysen Günel Özcan, Di̇cle Güç
Turkish Journal of Medical Sciences
Aims: Drug resistance is a major obstacle for a successful cancer therapy. Cell adhesion mediated drug resistance (CAM-DR) is a novel type of drug resistance and generated via interaction of cancer cells with the microenvironment. In this study, CAM-DR phenotype was analyzed in HL60 acute myeloid leukemia (AML) cells. Materials and Methods: Fibronectin (FN) adherence of HL60 cells was tested by a colorimetric adhesion assay. Flow cytometry analyses were performed to evaluate doxorubicin-induced apoptosis and to determine cell cycle status. Proliferation rate was evaluated by [^3H]-thymidine incorporation assay. Western blot and RT-PCR were used for analysis of the factors involved …
Seminal Plasma Transforming Growth Factor-\Beta (Tgf-\Beta) And Epidermal Growth Factor (Egf) Levels In Patients With Varicocele, Üçler Kisa, M. Murad Başar, Mehmet Ferhat, Osman Çağlayan
Seminal Plasma Transforming Growth Factor-\Beta (Tgf-\Beta) And Epidermal Growth Factor (Egf) Levels In Patients With Varicocele, Üçler Kisa, M. Murad Başar, Mehmet Ferhat, Osman Çağlayan
Turkish Journal of Medical Sciences
Aims: The aim of this study was to analyze seminal plasma epidermal growth factor (EGF) and transforming growth factor-\beta (TGF-\beta) levels in infertile patients with varicocele and normal fertile cases, and to evaluate the relationships between seminal plasma EGF and TGF-\beta, seminal parameters and serum hormone levels. Materials and Methods: A total of 100 patients with varicocele were enrolled into the study. Semen analyses were performed after 2 and 5 days of sexual abstinence. These patients were divided into two groups based on the results of semen analysis as oligoasthenoteratozoospermia (Group 1) and normal semen analysis (Group 2). Additionally, 100 …
Cisplatin Causes Oxidation In Rat Liver Tissues: Possible Protective Effects Of Antioxidant Food Supplementation, Aslihan Avci, Recep Çeti̇n, İmge B. Ergüder, Erdi̇nç Devri̇m, Bülent Kiliçoğlu, Özden Çandir, H. Serdar Öztürk, İlker Durak
Cisplatin Causes Oxidation In Rat Liver Tissues: Possible Protective Effects Of Antioxidant Food Supplementation, Aslihan Avci, Recep Çeti̇n, İmge B. Ergüder, Erdi̇nç Devri̇m, Bülent Kiliçoğlu, Özden Çandir, H. Serdar Öztürk, İlker Durak
Turkish Journal of Medical Sciences
Aims: In this study, we aimed to investigate the possible molecular mechanism of cisplatin hepatotoxicity and to establish whether some natural antioxidant foods, namely dried black grape and tomato, may provide protection against cisplatin hepatotoxicity. Materials and Methods: Twenty-eight rats were used throughout the study. Cisplatin was administered intraperitoneally (i.p.) in a single dose (10 mg/kg). Antioxidant food supplementation was started three days before cisplatin treatment. There were 7 animals in each group (control, cisplatin, cisplatin plus dried black grape and cisplatin plus tomato juice). Rats were sacrificed 72 h after the treatment. The livers were removed and prepared for …
Review Of Syphilis Patient Records In İzmir State Venereal Diseases Clinic From 1994 To 2004, Meltem Işikgöz Taşbakan, Hüsnü Pullukçu, Şebnem Şenol, Tansu Yamazhan, Levent Kidak, Deni̇z Gökengi̇n
Review Of Syphilis Patient Records In İzmir State Venereal Diseases Clinic From 1994 To 2004, Meltem Işikgöz Taşbakan, Hüsnü Pullukçu, Şebnem Şenol, Tansu Yamazhan, Levent Kidak, Deni̇z Gökengi̇n
Turkish Journal of Medical Sciences
Aim: The aim of this study was to evaluate patients attending a sexually transmitted infection (STI) outpatient clinic with a presumptive or definitive diagnosis of syphilis with regard to demographic characteristics, clinical findings, diagnostic criteria, treatment regimens and follow-up data over a 10-year period. Materials and Methods: The records of patients who had a presumptive/definitive diagnosis of syphilis [according to Centers for Disease Control (CDC) criteria] and who were referred to the İzmir State Venereal Diseases Outpatient Clinic or who were diagnosed in the clinic between 1994 and 2004 were reviewed retrospectively. Results: A total of 689 patients were included …
Is Ghrelin A Natural Anti-Microbial Agent?, Süleyman Aydin, Hi̇kmet Geçki̇l, Nermi̇n Kiliç, Fazi̇let Erman, S. Sirri Kiliç, Özfer Yeşi̇lada
Is Ghrelin A Natural Anti-Microbial Agent?, Süleyman Aydin, Hi̇kmet Geçki̇l, Nermi̇n Kiliç, Fazi̇let Erman, S. Sirri Kiliç, Özfer Yeşi̇lada
Turkish Journal of Medical Sciences
No abstract provided.
Neural Tube Defects And 19 Bp Deletion Within Intron-1 Of Dihydrofolate Reductase Gene, Nejat Akar, Ece Akar, Yonca Eği̇n, Gülhi̇s Deda, Saadet Arsan, Mesi̇ha Eki̇m
Neural Tube Defects And 19 Bp Deletion Within Intron-1 Of Dihydrofolate Reductase Gene, Nejat Akar, Ece Akar, Yonca Eği̇n, Gülhi̇s Deda, Saadet Arsan, Mesi̇ha Eki̇m
Turkish Journal of Medical Sciences
Aims: Dihydrofolate reductase (DHFR) is necessary for the reduction of the ingested folates before they are used in the body metabolism. Thus, the DHFR enzyme has an important role in folate supplementation and the DHFR gene is a strong candidate for a teratogenic locus for neural tube defects (NTDs). There is a 19 bp deletion within the first intron of the DHFR gene, which may have an effect on folate reduction. We thus studied this mutation in Turkish spina bifida patients and their mothers to determine whether there is an association with the occurrence of NTD. Materials and Methods: The …
Functional Vitamin B12 Deficiency Represented By Elevated Urine Methylmalonic Acid Levels In Patients With Migraine, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe, Hakan Tekeli̇, Mehmet Güney Şenol
Functional Vitamin B12 Deficiency Represented By Elevated Urine Methylmalonic Acid Levels In Patients With Migraine, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe, Hakan Tekeli̇, Mehmet Güney Şenol
Turkish Journal of Medical Sciences
Aims: Although vitamin B12 is currently used as a treatment option in patients with migraine, a possible cobalamin deficiency in those patients has not yet been investigated. In this study, we aimed to investigate cobalamin metabolism in patients with migraine. Materials and Methods: Fifty women having migraine without aura were matched with healthy controls (n=6) with the same age distribution. Fasting serum vitamin B12, folate, plasma total homocysteine (tHcy) and first morning urine methylmalonic acid (MMA) levels were determined in patient and control groups. Statistical differences in laboratory parameters between patient and control groups were analyzed by SPSS for Windows …
A Study Of Learning Assessment Of Personal Hygiene Skills Of Mentally Retarded Individuals In Drop-In Day Care Services, Fi̇gen Ar, Esra Kiliç, Ayşegül Akbay Yarpuzlu
A Study Of Learning Assessment Of Personal Hygiene Skills Of Mentally Retarded Individuals In Drop-In Day Care Services, Fi̇gen Ar, Esra Kiliç, Ayşegül Akbay Yarpuzlu
Turkish Journal of Medical Sciences
Aim: The aim of the study was to assess the success and efficiency of the training practices for acquisition of basic personal hygiene skills and behavior of hand washing and soiling in a relatively heterogeneous group of individuals receiving care from a drop-in day care/special education service. We also analyzed etiologies of the causes of discrepancies in learning behavior implying a need for differentiation of intellectually disabled individuals who are candidates for continuous long-term institutional medical care from those who can be integrated into the community through special education. Materials and Methods: The study included 30 participants with mental retardation …
Clinical And Rhinoscintigraphic Evaluation Of Oral Macrolides In The Management Of Sinonasal Polyposis, Emi̇ne Aydin, Hülya Ortapamuk, Hakan Korkmaz, Engi̇n Dursun, Adi̇l Eryilmaz, Güleser Saylam, Muharrem Dağli
Clinical And Rhinoscintigraphic Evaluation Of Oral Macrolides In The Management Of Sinonasal Polyposis, Emi̇ne Aydin, Hülya Ortapamuk, Hakan Korkmaz, Engi̇n Dursun, Adi̇l Eryilmaz, Güleser Saylam, Muharrem Dağli
Turkish Journal of Medical Sciences
Aim: To document the efficacy of low-dose long-term oral macrolide treatment in the management of sinonasal polyposis. The study was designed prospectively in a group of patients with sinonasal polyposis and negative history of surgery. Materials and Methods: Ten patients were administered roxithromycin (RXM) 150 mg/day single oral dose for eight weeks. All patients underwent Tc-99m rhinoscintigraphic evaluation of mucociliary activity and endoscopic evaluation before and after the treatments. Response to treatment, in terms of rhinoscintigraphic and endoscopic improvement, was assessed. Results: Of the 10 patients, 7 were male and 3 female, with an average age of 46 years (27-74). …
Dermatomyositis Associated With Hemophagocytic Syndrome: A Case Report/Review Of The Literature, Engi̇n Sennaroğlu, Berçem Ayçi̇çek Doğan, Hasan Tunca, Bariş Yilmaz, Gamze Gedi̇k, Burak Ci̇velek, Si̇nem Tümtürk
Dermatomyositis Associated With Hemophagocytic Syndrome: A Case Report/Review Of The Literature, Engi̇n Sennaroğlu, Berçem Ayçi̇çek Doğan, Hasan Tunca, Bariş Yilmaz, Gamze Gedi̇k, Burak Ci̇velek, Si̇nem Tümtürk
Turkish Journal of Medical Sciences
Hemophagocytic syndrome (HPS) is a disorder that might be transferred genetically due to an autosomal recessive genetic defect of the long arm of chromosome 9 and chromosome 10 (9q21.3-22 and 10q21-22), termed as primary hemophagocytic syndrome (PHPS) or familial hemophagocytic hemophagocytosis (FHPS) and it may be associated with a variety of infections, malignant neoplasms, drugs, autoimmune diseases and various immuno deficiencies, termed as secondary hemophagocytic syndrome (SHPS). For most patients with HPS, the outcome is rapid and fatal unless the diagnosis is made early and followed by prompt therapeutic intervention. Fever, hepatosplenomegaly, cytopenia, hypertriglyceridemia and/or hypofibrinogenemia, low erythrocyte sedimentation rate, …
Coexistence Of Tuberculosis Verrucosa Cutis With Scrofuloderma, Müzeyyen Gönül, Ülker Gül, Arzu Kiliç, Seçi̇l Soylu, Murat Demi̇ri̇z, Ayhan Kubar
Coexistence Of Tuberculosis Verrucosa Cutis With Scrofuloderma, Müzeyyen Gönül, Ülker Gül, Arzu Kiliç, Seçi̇l Soylu, Murat Demi̇ri̇z, Ayhan Kubar
Turkish Journal of Medical Sciences
Although cutaneous tuberculosis is rarely seen in developed countries, it is still commonly seen in developing countries. Tuberculosis verrucosa cutis (TVC) is a form of cutaneous tuberculosis that is caused by direct inoculation of Mycobacterium tuberculosis into the skin through open wounds or abrasions in sensitized individuals and is rarely seen in our country. Scrofuloderma is a form of cutaneous tuberculosis that occurs by direct spread of Mycobacterium tuberculosis from a contiguous structure. Coexistence of TVC and scrofuloderma is extremely rare. A 35-year-old woman presented to our clinic with a lesion on the dorsum of her left hand. Dermatological examination …
Different Segregation Of Chromosomes 5 And 7 In Two Generations And Related Phenotypic Findings, Osman Demi̇rhan, Nurdan Tunali, Şeyda Erdoğan, Deni̇z Taştemi̇r, Erdal Tunç
Different Segregation Of Chromosomes 5 And 7 In Two Generations And Related Phenotypic Findings, Osman Demi̇rhan, Nurdan Tunali, Şeyda Erdoğan, Deni̇z Taştemi̇r, Erdal Tunç
Turkish Journal of Medical Sciences
Aim: In this study, we aimed to put forth the clinical consequences of rearrangement between chromosomes 5 and 7 observed in one fetus, one newborn infant (siblings) and their parents. Materials and Methods: We performed chromosomal analysis in one fetus, one newborn (siblings) and their parents, applying standard protocols to fetal blood, amniotic fluid and peripheral blood samples. We performed both prenatal and postnatal karyotyping in the newborn infant. Results: We described rearrangements related to chromosomes 5 and 7 in these individuals. We found that the curetted fetus and newborn infant were carriers of unbalanced and balanced rearrangements, respectively. We …
Effects Of Omega-3 On Lipid Peroxidation And Antioxidant Enzymes In Mk-801 Induced Schizophrenic Rat Testis, Bi̇rsen Özyurt, Fi̇kret Erdemi̇r, Beki̇r Suha Parlaktaş, Hüseyi̇n Özyurt, Hasan Erdoğan, Ayten Türkkani Tunç
Effects Of Omega-3 On Lipid Peroxidation And Antioxidant Enzymes In Mk-801 Induced Schizophrenic Rat Testis, Bi̇rsen Özyurt, Fi̇kret Erdemi̇r, Beki̇r Suha Parlaktaş, Hüseyi̇n Özyurt, Hasan Erdoğan, Ayten Türkkani Tunç
Turkish Journal of Medical Sciences
No abstract provided.
Serum Transforming Growth Factor-Β (Tgf-Β), Matrix Metalloproteinase-2 (Mmp-2), Matrix Metalloproteinase-9 (Mmp-9) And Tissue Inhibitors Of Metalloproteinase (Timp-1) Levels In Childhood Asthma, Fi̇gen Doğu, Ali̇şan Yildiran, Deni̇z Güloğlu, Funda Erol Çi̇pe, Mutlu Yüksek, Emel Babacan, Aydan İki̇nci̇oğullari
Serum Transforming Growth Factor-Β (Tgf-Β), Matrix Metalloproteinase-2 (Mmp-2), Matrix Metalloproteinase-9 (Mmp-9) And Tissue Inhibitors Of Metalloproteinase (Timp-1) Levels In Childhood Asthma, Fi̇gen Doğu, Ali̇şan Yildiran, Deni̇z Güloğlu, Funda Erol Çi̇pe, Mutlu Yüksek, Emel Babacan, Aydan İki̇nci̇oğullari
Turkish Journal of Medical Sciences
Aims: Airway remodelling is a characteristic feature of asthma and is a dynamic process involving extracellular matrix (ECM) production and its degradation. In this regard, the matrix metalloproteinases (MMPs) and their specific inhibitors known as tissue inhibitors of metalloproteinases (TIMPs) have been shown to be important in this process. In the present study, transforming growth factor (TGF)-\beta, MMP-2, MMP-9 and TIMP-1 levels in serum samples of children with stable asthma and healthy controls were evaluated to determine whether these levels show any difference between asthmatic and healthy children and whether or not these levels change with atopic status. Materials and …
Laparoscopic Cystogastrostomy For The Management Of Pancreatic Pseudocysts, Kaya Saribeyoğlu, Sali̇h Pekmezci̇, Ece Kol, Meti̇n Kapan, Hasan Taşçi
Laparoscopic Cystogastrostomy For The Management Of Pancreatic Pseudocysts, Kaya Saribeyoğlu, Sali̇h Pekmezci̇, Ece Kol, Meti̇n Kapan, Hasan Taşçi
Turkish Journal of Medical Sciences
Aims: To assess the value of laparoscopic cystogastrostomy in the treatment of pancreatic pseudocysts. Materials and Methods: Patients who underwent laparoscopic surgery for pancreatic pseudocysts were included in the study. All the cysts were non-resolving, symptomatic and large, as a result of acute pancreatitis. Laparoscopic cystogastrostomies were performed by either anterior transgastric or posterior techniques. Results: From February 2001 to November 2006, seven patients were included into the study. The etiology of pancreatitis was gallstone disease in six cases and hyperlipidemia in one. The mean age was 58.7 years (52-69) and the mean pseudocyst size was 15.1 cm (7-20). Transgastric …
Mixed Medullary-Follicular Thyroid Carcinoma : A Report Of Two Cases, Özge Han, Tuba Ünal, Selda Seçki̇n, Sezer Kulaçoğlu
Mixed Medullary-Follicular Thyroid Carcinoma : A Report Of Two Cases, Özge Han, Tuba Ünal, Selda Seçki̇n, Sezer Kulaçoğlu
Turkish Journal of Medical Sciences
Mixed medullary-follicular carcinoma is an uncommon tumor of the thyroid. It is characterized by histological and immunohistochemical features of both follicular and parafollicular C cells. We report two female patients, aged 26 and 78 years, with mixed medullary-follicular carcinoma. Histologically, the tumors are composed of follicular carcinoma areas and solid nests of polygonal cells consistent with medullary carcinoma. Immunohistochemically, thyroglobulin and calcitonin positivity was detected. Precise diagnosis of mixed medullary-follicular carcinoma is essential for accurate treatment and follow-up.
Placental Heat Shock Protein 70 Overexpression Confers Resistance Against Oxidative Stress In Preeclampsia, Ekambaram Padmini, Bose Vijaya Geetha
Placental Heat Shock Protein 70 Overexpression Confers Resistance Against Oxidative Stress In Preeclampsia, Ekambaram Padmini, Bose Vijaya Geetha
Turkish Journal of Medical Sciences
Aims: Preeclampsia is a hypertensive disorder of human pregnancy and a leading cause of premature delivery and fetal growth retardation. The purpose of this study was to evaluate the expression of heat shock protein 70 (HSP70), both constitutive (HSC70) and induced (HSP70) forms, along with oxidative stress status in the placental tissues of normotensive (control group) and preeclamptic pregnancies. Materials and Methods: Placental samples were collected after delivery from normotensive pregnancies and preeclamptic patients (n = 20, each). Lipid peroxidation product malondialdehyde (MDA) and nitrite and nitrate levels, along with antioxidants such as superoxide dismutase (SOD) and glutathione peroxidase (GPx) …
Oxidative Stress Of Radioiodine Treatment In Patients With Hyperthyroidism, Mustafa Yildiz, Ekrem Çi̇çek, Burçi̇n Aşkim Gümüş, Celal Çerçi̇, Süreyya Çerçi̇, Erol Eroğlu, Namik Deli̇baş
Oxidative Stress Of Radioiodine Treatment In Patients With Hyperthyroidism, Mustafa Yildiz, Ekrem Çi̇çek, Burçi̇n Aşkim Gümüş, Celal Çerçi̇, Süreyya Çerçi̇, Erol Eroğlu, Namik Deli̇baş
Turkish Journal of Medical Sciences
Aims: To investigate radiation-induced oxidative damage in erythrocytes after administration of radioiodine-131 (^{131}I) in patients with hyperthyroidism. Materials and Methods: Twenty patients with hyperthyroidism (11 F, 9 M) treated with ^{131}I were included into the study. Blood samples were taken from patients just before, 1 hour after and 3 hours after applying radioiodine. Malondialdehyde (MDA) and levels of antioxidant enzymes such as glutathione peroxidase (GPX), superoxide dismutase (SOD) and catalase (CAT) were measured to evaluate the radiation-induced oxidative damage. Results: We found that enzyme activities of SOD, GPX and CAT were decreased 1 hour and 3 hours after radioiodine treatment …
The Effect Of Isoflavones On Bone Mass And Bone Remodelling Markers In Postmenopausal Women, Ni̇lgün Öztürk Turhan, Fatma Bolkan, Candan İltemi̇r Duvan, Yasemi̇n Ardiçoğlu
The Effect Of Isoflavones On Bone Mass And Bone Remodelling Markers In Postmenopausal Women, Ni̇lgün Öztürk Turhan, Fatma Bolkan, Candan İltemi̇r Duvan, Yasemi̇n Ardiçoğlu
Turkish Journal of Medical Sciences
Aim: Recently, isoflavones have attracted attention for their potential roles in the prevention and treatment of estrogen-related osteoporosis. However, the optimal dosage and the components responsible for the favorable effects of isoflavones on bone in humans are still unclear. This study aims to investigate the effect of low-dose isoflavones on bone mineral density (BMD) and on biochemical markers of bone turnover in early postmenopausal women. Materials and Methods: Ninety participants between 42-59 years of age were randomly assigned to receive twice a day either isoflavone tablet (n:45) that provided 29.8 mg genistein, 7.8 mg daidzein, and 2.4 mg glycitein per …
Prevalence Of The Metabolic Syndrome In A Rural Turkish Population: Comparison And Concordance Of Two Diagnostic Criteria, Ayfer Gemalmaz, Serpi̇l Aydin, Okay Başak, Güzel Di̇şçi̇gi̇l, Aslihan Karul
Prevalence Of The Metabolic Syndrome In A Rural Turkish Population: Comparison And Concordance Of Two Diagnostic Criteria, Ayfer Gemalmaz, Serpi̇l Aydin, Okay Başak, Güzel Di̇şçi̇gi̇l, Aslihan Karul
Turkish Journal of Medical Sciences
Aim: This study was performed to compare the prevalence of the metabolic syndrome (MES) according to the International Diabetes Federation (IDF) and Adult Treatment Panel III (ATPIII) definitions in a population-based sample and to determine the concordance of the definitions. Materials and Methods: A total of 244 adults aged >=20 years (145 women and 99 men), selected systematically from household registration cards in a rural village in West Anatolia, were analyzed. Kappa test was done to examine the agreement between the definitions. Results: The mean age of the group was 46.9 ± 14.9 years. The prevalence of MES using ATPIII …
Is The Gök Atlas Sufficiently Reliable For Forensic Age Determination Of Turkish Children?, Bora Büken, Erhan Büken, Alp Alper Şafak, Burhan Yazici, Zerri̇n Erkol, Ati̇lla Mayda
Is The Gök Atlas Sufficiently Reliable For Forensic Age Determination Of Turkish Children?, Bora Büken, Erhan Büken, Alp Alper Şafak, Burhan Yazici, Zerri̇n Erkol, Ati̇lla Mayda
Turkish Journal of Medical Sciences
Aim: We investigated whether the contemporary use of the Gök Atlas method is sufficiently reliable for forensic age estimations of Turkish children. Materials and Methods: Plain radiographs of 248 females and 298 males between 11 and 22 years of age were taken. Paired sample t-tests, Pearson correlation coefficients, and linear regression were used to determine the differences and model the relationships between mean skeletal (bone) age (BA) and mean chronological age (CA), using SPSS 11.5 statistical software. Results: In all cases, the CA and BA scores were significantly different and showed high correlation (P < 0.05). The regression model was significant (P < 0.01). According to age groups, the BA was greater than the CA for all age groups by 0.09-3.10 years for boys and 0.44-3.05 years for girls, and this difference was significant for all age groups >14 years for boys and for …
The Effect Of Pregnancy On The Physical And Sexual Abuse Of Women That Presented To A State Hospital In Trabzon, Turkey, Murat Topbaş, Mesut Ünsal, Gamze Çan, Aynur Bacak, Şükrü Özgün
The Effect Of Pregnancy On The Physical And Sexual Abuse Of Women That Presented To A State Hospital In Trabzon, Turkey, Murat Topbaş, Mesut Ünsal, Gamze Çan, Aynur Bacak, Şükrü Özgün
Turkish Journal of Medical Sciences
Aim: To investigate the prevalence of the physical and sexual abuse of women before and during pregnancy, and to determine whether pregnancy affected the abuse of women. Materials and Methods: This study was performed at a state hospital in the Turkish city of Trabzon and included 762 women that gave birth between July and September 2004. A questionnaire was administered during a face-to-face interview to collect data on sociodemographic factors, exposure to abuse before and during pregnancy, and the women´s post-abuse attitudes. Data were analyzed using the McNemar and chi-square tests. Results: It was determined that 8.8% of the women …
Co-Existence Of Intrahepatic Bile Duct Adenoma And Colonic Adenocarcinoma, Gülen Akyol, Nüket Üzüm, Nusret Akyürek, Bülent Menteş
Co-Existence Of Intrahepatic Bile Duct Adenoma And Colonic Adenocarcinoma, Gülen Akyol, Nüket Üzüm, Nusret Akyürek, Bülent Menteş
Turkish Journal of Medical Sciences
Intrahepatic bile duct adenoma (BDA) is a rare benign tumor of the liver that is usually diagnosed by microscopic examination. Most cases are incidentally discovered during surgery or autopsy. Here, we report the co-existence of colonic adenocarcinoma and intrahepatic BDA mimicking metastasis in a 62-year-old man. The patient underwent metastasectomy because of the presence of colonic adenocarcinoma diagnosed at almost the same time. The diagnosis was benign in frozen sections intraoperatively and total colectomy was performed during the same operation. BDA should be included in the diseases to be differentiated from hepatic primary or metastatic tumors.
Twin Sisters With Unique Septate Uterus And Longitudinal Vaginal Septum, Ni̇lgün Öztürk Turhan, Candan İltemi̇r Duvan, Hi̇lal Yuvaci
Twin Sisters With Unique Septate Uterus And Longitudinal Vaginal Septum, Ni̇lgün Öztürk Turhan, Candan İltemi̇r Duvan, Hi̇lal Yuvaci
Turkish Journal of Medical Sciences
The septate uterus is the most common form of structural uterine anomalies. A rare developmental variant is a complete septate uterus with cervical duplication and a complete vaginal septum. Experiences with these unique uterine anomalies are limited only to case reports. Although there have been a few families in which members are affected similarly, there are no reports in the literature describing dizygotic twins with the same congenital uterine malformation, as seen in our cases. A 28-year-old woman and her dizygotic twin sister who had spontaneous abortion history were identified in our practice with complete septate uterus, cervical duplication and …
Purtscher´S Retinopathy: An Unusual Association With A Complicated Mandibular Fracture, Tongabay Cumurcu, Hüseyi̇n Yardim, Mehmet Güven, Raşi̇t Kiliç, Ni̇lüfer Özkan
Purtscher´S Retinopathy: An Unusual Association With A Complicated Mandibular Fracture, Tongabay Cumurcu, Hüseyi̇n Yardim, Mehmet Güven, Raşi̇t Kiliç, Ni̇lüfer Özkan
Turkish Journal of Medical Sciences
We present a case of unilateral traumatic retinal angiopathy following a mandibular fracture. An 11-year-old child involved in a bicycle accident developed Purtscher´s retinopathy in the left eye with retinal hemorrhages, cotton wool spots, and optic disc swelling on funduscopy. The visual acuity in this eye was counting fingers at one meter.
Pten Expression In Primary Prostate Carcinoma In Turkish Patients, Di̇lek Ertoy Baydar, Haluk Özen, Osman Saraçbaşi, Erdem Karabulut
Pten Expression In Primary Prostate Carcinoma In Turkish Patients, Di̇lek Ertoy Baydar, Haluk Özen, Osman Saraçbaşi, Erdem Karabulut
Turkish Journal of Medical Sciences
Aim: Prostatic adenocarcinoma shows remarkable variability in the incidence and biological behavior between populations from different races and geographical regions of the world. PTEN has been reported as the most commonly mutated tumor suppressor gene in prostate cancer. Incidence of PTEN alterations occurring in prostatic carcinoma has not been studied previously in the Turkish population. Materials and Methods: We examined PTEN protein expression immunohistochemically and its significance in 69 primary prostate cancer patients from Turkey. Two tissue microarrays constructed by 0.6 mm cores from radical prostatectomy specimens were used. Clinical information for all patients was obtained from hospital records. Results: …