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Full-Text Articles in Medicine and Health Sciences

Biochemical And Molecular Characterization Of The Prostate-Specific Membrane Antigen (Psma), John Karl Troyer Oct 1995

Biochemical And Molecular Characterization Of The Prostate-Specific Membrane Antigen (Psma), John Karl Troyer

Theses and Dissertations in Biomedical Sciences

Prostate cancer is the most common malignancy and the second leading cause of cancer death in males in the United States. Additionally, the number of deaths attributed to prostate cancer is increasing at a rate of approximately 8% a year. Development of new diagnostic and therapy strategies are needed in order to improve the life expectancy of patients with this disease. One tool which may allow for improvements in prostate cancer diagnosis and therapy is the monoclonal antibody (MAb) 7E11-C5.3 which was first described in 1987. Since then, the antigen recognized by MAb 7E11-C5.3 has been named the prostate specific …


Effectiveness Of Dna Probe Technology In Distinguishing Among Gingival Health, Mild-Moderate Periodontitis, And Severe Periodontitis In Human Oral Sites, Juliana J. Kim Apr 1995

Effectiveness Of Dna Probe Technology In Distinguishing Among Gingival Health, Mild-Moderate Periodontitis, And Severe Periodontitis In Human Oral Sites, Juliana J. Kim

Dental Hygiene Theses & Dissertations

The purpose of this investigation was to determine if there is a difference in the type of microorganisms found in oral sites classified as gingival health, mild-moderate periodontitis, or severe periodontitis as measured by the DMDx* Test. A purposive sample of one hundred oral sites was selected from adult patients. Subjects were excluded from the study based on: the presence of any systemic disorders, communicable diseases, diabetic conditions, blood dyscrasias, congenital heart disease, rheumatic heart disease, pregnancy, history of periodontal surgery, prosthetic joint replacement, hypertensive heart disease, or any medications that might alter the gingival tissues (e.g. antibiotics, hormonal therapy, …