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Articles 1 - 21 of 21
Full-Text Articles in Medicine and Health Sciences
Effect Of Testosterone On Inflammatory Markers In The Development Of Early Atherogenesis In The Testicular-Feminized Mouse Model, Daniel Kelly, Donna Sellers, M. Woodroofe, T. Jones, Kevin Channer
Effect Of Testosterone On Inflammatory Markers In The Development Of Early Atherogenesis In The Testicular-Feminized Mouse Model, Daniel Kelly, Donna Sellers, M. Woodroofe, T. Jones, Kevin Channer
Donna Sellers
Background: Low levels of serum testosterone in men are associated with cardiovascular disease. Clinical studies show that testosterone replacement therapy (TRT) can improve symptoms of cardiovascular disease and reduce the inflammatory burden evident in atherosclerosis.
Aim: We used an in vivo animal model to determine whether testosterone influences mediators of vascular inflammation as part of its beneficial effects on atherogenesis.
Methods: Testicular-feminized (Tfm) mice, which express low endogenous testosterone and a non-functional androgen receptor (AR), were used to assess the effect of androgen status on atheroma formation, serum lipids, and inflammatory mediators. Tfm mice were fed a high-cholesterol diet, received …
Malignant Peripheral Nerve Sheath Tumor (Mpnst): An Overview With Emphasis On Pathology, Imaging And Management Strategies., Timothy C. Beer
Malignant Peripheral Nerve Sheath Tumor (Mpnst): An Overview With Emphasis On Pathology, Imaging And Management Strategies., Timothy C. Beer
Timothy C Beer
MPNSTs are rare malignancies that are classically associated with pre-existing plexiform neurofibromas in neurofibromatosis type 1 (NF-1) patients, but also occur in association with radiation as well as sporadically in patients with no known risk factors. The typical presentation of sporadic MPNST is a new painless enlarging mass. The typical presentation of MPNST in an NF-1 patient is rapid enlargement or new onset of pain associated with a pre-existing plexiform neurofibroma. Although both MPNST and benign neurofibromas share in common the absence of neurofibromin function due to loss of both NF-1 alleles, malignant transformation to MPNST requires several additional aberrations, …
Neural Network Facilitated Analysis Of Stress In A Biological Species, Emmanuel Udoh, David Erbach, Ahmed Mustafa
Neural Network Facilitated Analysis Of Stress In A Biological Species, Emmanuel Udoh, David Erbach, Ahmed Mustafa
Ahmed Mustafa Dr.
No abstract provided.
Susceptibility Of Rainbow Trout Oncorhynchus Mykiss, Coho Salmon Oncorhynchus Kisutch And Atlantic Salmon Salmo Salar Experimental Infection With Sea Lice Lepeophtheirus Salmonis, M. Fast, N. Ross, Ahmed Mustafa, D. Sims, S. Johnson, G. Conboy, D. Speare, G. Johnson, J. Burka
Susceptibility Of Rainbow Trout Oncorhynchus Mykiss, Coho Salmon Oncorhynchus Kisutch And Atlantic Salmon Salmo Salar Experimental Infection With Sea Lice Lepeophtheirus Salmonis, M. Fast, N. Ross, Ahmed Mustafa, D. Sims, S. Johnson, G. Conboy, D. Speare, G. Johnson, J. Burka
Ahmed Mustafa Dr.
No abstract provided.
Effects Of High Ph On Unionized Ammonia And Their Combined Effects On The Stress Physiology Of Steelhead Trout (Oncorhynchus Mykiss) Reared In Recirculating Aquaculture Systems (Short Communication), Ahmed Mustafa, T. Keefe, P. Quarrar
Effects Of High Ph On Unionized Ammonia And Their Combined Effects On The Stress Physiology Of Steelhead Trout (Oncorhynchus Mykiss) Reared In Recirculating Aquaculture Systems (Short Communication), Ahmed Mustafa, T. Keefe, P. Quarrar
Ahmed Mustafa Dr.
No abstract provided.
Primary Stress Responses Of Common Carp, Cyprinus Carpio Exposed To Copper Toxicity, Mathan Ramesh, Ahmed Mustafa, Sathyanarayanan Senthil Kumaran, Chokkalingam Kavith, Monoharan Saravanan
Primary Stress Responses Of Common Carp, Cyprinus Carpio Exposed To Copper Toxicity, Mathan Ramesh, Ahmed Mustafa, Sathyanarayanan Senthil Kumaran, Chokkalingam Kavith, Monoharan Saravanan
Ahmed Mustafa Dr.
Copper is a heavy metal, and an aquatic pollutant, known for its bio-accumulative and non-biodegradable properties. In the aquatic ecosystems, acute and sublethal concentrations of copper may be linked to a variety of effects. Recently, hormones, particularly those regulating vital functions, such as osmoregulation, energy metabolism, and reproduction, may be used as potential biomarkers for sublethal toxicity studies. In the present study, the potential effect of a heavy metal—copper on hormonal changes (cortisol and prolactin) in an economically important fresh-water fish—common carp, Cyprinus carpio, was examined.
Effects Of Iodized Feed On Stress Modulation In Steelhead Trout, Oncorhynchus Mykiss (Walbaum), Monica Gensic, Patrick Wissing, Timothy Keefe, Ahmed Mustafa
Effects Of Iodized Feed On Stress Modulation In Steelhead Trout, Oncorhynchus Mykiss (Walbaum), Monica Gensic, Patrick Wissing, Timothy Keefe, Ahmed Mustafa
Ahmed Mustafa Dr.
In the aquaculture industry, the physiological systems of fish can be chronically stressed by various biological, chemical and physical factors. Chronic stress leads to a decrease in the overall health and growth of the fish, making them more prone to diseases. Dietary iodine has been shown to reduce this stress response in chickens and increase disease resistance in dairy cattle, but the mechanisms by which iodine affects stress resistance and immunocompetency is not completely understood and has not been extensively studied in fish. This study investigated the effects of iodized feed as a nutritional supplement in relation to stress modulation …
Teaching Stress Physiology Using Zebrafish (Danio Rerio), Michael Cooper, Shree Dhawale, Ahmed Mustafa
Teaching Stress Physiology Using Zebrafish (Danio Rerio), Michael Cooper, Shree Dhawale, Ahmed Mustafa
Ahmed Mustafa Dr.
A straightforward and inexpensive laboratory experiment is presented that investigates the physiological stress response of zebrafish after a 5 °C increase in water temperature. This experiment is designed for an undergraduate physiology lab and allows students to learn the scientific method and relevant laboratory techniques without causing significant stress to animals. An additional experimental design and a set of additional questions for lab report are also included.
Development Of A Method For Extracting Macrophages From Zebrafish, Danio Rerio And Their Use In Assessing Stress, Ahmed Mustafa, Shree Dhawale, Shrikrishna Dhawale
Development Of A Method For Extracting Macrophages From Zebrafish, Danio Rerio And Their Use In Assessing Stress, Ahmed Mustafa, Shree Dhawale, Shrikrishna Dhawale
Ahmed Mustafa Dr.
No abstract provided.
Estimating The Cost Of Sea Lice To Salmon Aquaculture In Atlantic Canada, Ahmed Mustafa, Wimal Rankadua, Pat Campbell
Estimating The Cost Of Sea Lice To Salmon Aquaculture In Atlantic Canada, Ahmed Mustafa, Wimal Rankadua, Pat Campbell
Ahmed Mustafa Dr.
Parasitic sea lice are serious problems in aquaculture. The true cost of these parasites is unknown. We demonstrate the economic burden imposed by sea lice, so that researchers, aquatic specialists, and policy makers can approximate the economic cost of this problem and work towards developing alternative control methods.
Skin Morphology And Humoral Non-Specific Defense Parameters Of Mucus And Plasma In Rainbow Trout, Coho And Atlantic Salmon, M. Fast, N. Ross, Ahmed Mustafa, D. Sims, J. Burka
Skin Morphology And Humoral Non-Specific Defense Parameters Of Mucus And Plasma In Rainbow Trout, Coho And Atlantic Salmon, M. Fast, N. Ross, Ahmed Mustafa, D. Sims, J. Burka
Ahmed Mustafa Dr.
No abstract provided.
Sustainable Brackish Water Shrimp Farming: A Serious Thought In India, Susmita Patnaik, Maryam Moshref, Ahmed Mustafa
Sustainable Brackish Water Shrimp Farming: A Serious Thought In India, Susmita Patnaik, Maryam Moshref, Ahmed Mustafa
Ahmed Mustafa Dr.
No abstract provided.
Factors Affecting The Susceptibility Of Sea Lice Infestations In Atlantic Salmon, Ahmed Mustafa, Wojciech Piasecki
Factors Affecting The Susceptibility Of Sea Lice Infestations In Atlantic Salmon, Ahmed Mustafa, Wojciech Piasecki
Ahmed Mustafa Dr.
No abstract provided.
Interspecific Differences Between Atlantic Salmon And Arctic Charr In Susceptibility To Infection With Larval And Adult Caligus Elongatus: Effect Of Skin Mucus Protein Profiles And Epidermal Histological Differences, Ahmed Mustafa, B. Mackinnon, W. Piasecki
Interspecific Differences Between Atlantic Salmon And Arctic Charr In Susceptibility To Infection With Larval And Adult Caligus Elongatus: Effect Of Skin Mucus Protein Profiles And Epidermal Histological Differences, Ahmed Mustafa, B. Mackinnon, W. Piasecki
Ahmed Mustafa Dr.
No abstract provided.
Assessment Of The Hemorheological Profile Of Koala And Echidna, Oguz Baskurt, Sonya Marshall-Gradisnik, Michael Pyne, Michael Simmonds, Ekua Brenu, Rhys Christy, Herbert Meiselman
Assessment Of The Hemorheological Profile Of Koala And Echidna, Oguz Baskurt, Sonya Marshall-Gradisnik, Michael Pyne, Michael Simmonds, Ekua Brenu, Rhys Christy, Herbert Meiselman
Sonya Marshall-Gradisnik
Koala, a marsupial, and echidna, a monotreme, are mammals native to Australia. Blood viscosity (62.5-1250 s-1), red blood cell (RBC) deformability, RBC aggregation, aggregability and surface charge, and hematological parameters were measured in blood samples from six koalas and six echidnas and compared to adult human blood. Koala had the largest RBC mean cell volume (107.7±2.6 fl) compared to echidna (81.3±2.6 fl) and humans (88.4±1.2 fl). Echidna blood exhibited the highest viscosity over the entire range of shear rates. Echidna RBC were significantly less deformable than koala RBC but more deformable than human RBC. Echidna RBC had significantly lower aggregability …
Sudden Infant Death Syndrome: Postulated Role Of Impaired Vasoactive Neuropeptide-Related Inflammatory Modulation, Donald Staines, Ekua Brenu, Sonya Marshall-Gradisnik
Sudden Infant Death Syndrome: Postulated Role Of Impaired Vasoactive Neuropeptide-Related Inflammatory Modulation, Donald Staines, Ekua Brenu, Sonya Marshall-Gradisnik
Sonya Marshall-Gradisnik
Sudden infant death syndrome (SIDS) has been extensively investigated in the context of infection as a contributing factor in the death of otherwise apparently healthy infants. A number of infectious agents have been implicated suggesting the causal pathomechanism is related to infection, but not necessarily solely attributable to any one type of infection. An alternative provocative hypothesis is that of post-infection autoimmunity affecting critical novel neurotransmitters of the vasoactive neuropeptide family. Their role in respiratory and cardiac functioning together with novel hypotheses postulating their autoimmune compromise may suggest a role in SIDS etiology following infection. Animal models demonstrate their vital …
An In Vitro Microenvironment That Supports The Development Of A Novel Dendritic Cell From Bone Marrow And Spleen Hsc, Pravin Periasamy, Helen O'Neill
An In Vitro Microenvironment That Supports The Development Of A Novel Dendritic Cell From Bone Marrow And Spleen Hsc, Pravin Periasamy, Helen O'Neill
Helen O'Neill
No abstract provided.
Tedchnical Advance: In Vitro Production Of Distinct Dendritic-Like Antigen Presenting Cells From Self-Renewing Hematopoietic Stem Cells, Rebecca Hinton, Helen O'Neill
Tedchnical Advance: In Vitro Production Of Distinct Dendritic-Like Antigen Presenting Cells From Self-Renewing Hematopoietic Stem Cells, Rebecca Hinton, Helen O'Neill
Helen O'Neill
No abstract provided.
Molecular Definition Of A Hematopoietic Niche In Spleen, Pravan Periasamy, Helen O'Neill
Molecular Definition Of A Hematopoietic Niche In Spleen, Pravan Periasamy, Helen O'Neill
Helen O'Neill
No abstract provided.
Cold And Heat Pattern Of Rheumatoid Arthritis In Traditional Chinese Medicine: Distinct Molecular Signatures Indentified By Microarray Expression Profiles In Cd-4 Positive T Cell., C Lu, C Xiao, G Chen, M Jiang, Q Zha, X Yan, W Kong, Aiping Lu
Cold And Heat Pattern Of Rheumatoid Arthritis In Traditional Chinese Medicine: Distinct Molecular Signatures Indentified By Microarray Expression Profiles In Cd-4 Positive T Cell., C Lu, C Xiao, G Chen, M Jiang, Q Zha, X Yan, W Kong, Aiping Lu
Professor LU, Aiping
The research is aimed to explore the distinct molecular signatures in discriminating the rheumatoid arthritis patients with traditional Chinese medicine (TCM) cold pattern and heat pattern. Twenty patients with typical TCM cold pattern and heat pattern were included. Microarray technology was used to reveal gene expression profiles in CD4+ T cells. The signal intensity of each expressed gene was globally normalized using the R statistics program. The ratio of cold pattern to heat pattern in patients with RA at more or less than 1:2 was taken as the differential gene expression criteria. Protein-protein interaction information for these genes from databases …
In Vitro Differentiation Of Novel Antigen Presenting Cells, Sawang Petvises, Pravin Periasamy, Helen O'Neill
In Vitro Differentiation Of Novel Antigen Presenting Cells, Sawang Petvises, Pravin Periasamy, Helen O'Neill
Helen O'Neill
No abstract provided.