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- BRCA1 (1)
- BRCA2 (1)
- Decision making (1)
- Elevated risk perceptions (1)
- Enzyme replacement therapy (1)
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- Ethnic identity (1)
- Gaucher disease (1)
- Genetic counseling (1)
- Health related quality of life (1)
- Hereditary breast and ovarian cancer (1)
- Risk perception of teratogens (1)
- Risk-reducing salpingo-oophorectomy (1)
- Substrate reduction therapy (1)
- Teratogen (1)
- Teratogen counseling (1)
- Teratogenic risk perceptions (1)
- Treatment options (1)
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Ethnic Identity And Teratogenic Risk Perceptions, Katie M. Chan
Ethnic Identity And Teratogenic Risk Perceptions, Katie M. Chan
Dissertations & Theses (Open Access)
Elevated perceptions of teratogenic risk can cause anxiety and confusion among pregnant women. To assess whether ethnic identity and demographic factors can influence teratogenic risk perceptions, 194 pregnant women in Houston were surveyed using the Multigroup Ethnic Identity Measure (MEIM) and visual analog scales to quantify perceptions of teratogenic risk for common exposures during pregnancy. Overall, participants estimated an elevated baseline risk of 25% for birth defects among the general population. In addition, participants overestimated birth defect risks for specific exposures, such as alcohol and marijuana. Based on the MEIM scores, ethnic identity was not significantly associated with teratogenic risk …
Factors Influencing Uptake Of Risk-Reducing Salpingo-Oophorectomy By Brca1 And Brca2 Mutation Carriers, Victoria E. Breen
Factors Influencing Uptake Of Risk-Reducing Salpingo-Oophorectomy By Brca1 And Brca2 Mutation Carriers, Victoria E. Breen
Dissertations & Theses (Open Access)
Germline mutations in the BRCA1 and BRCA2 genes are associated with significantly increased risks for ovarian cancer. The National Comprehensive Cancer Network (NCCN) currently recommends that female BRCA mutation carriers undergo risk-reducing salpingo-oophorectomy (RRSO) after age 35; however, not all women elect this option. The purpose of this study was to prospectively survey women with BRCA mutations currently undergoing ovarian cancer screening about their intention to have an RRSO and the various factors influencing their decision. Of the 26 women who completed our survey, 26 (100%, CI: 86.8-100) plan to undergo an RRSO in their lifetime. The average woman reported …
No Difference In Health Related Quality Of Life Between Therapeutic Options For Type 1 Gaucher Disease, Victoria Wagner
No Difference In Health Related Quality Of Life Between Therapeutic Options For Type 1 Gaucher Disease, Victoria Wagner
Dissertations & Theses (Open Access)
Type 1 Gaucher disease (GD) is the most common lysosomal storage disorder. Previously, treatment for GD was limited to intravenous enzyme replacement therapy (ERT). ERT reduces symptoms and increases healthrelated quality of life (HRQoL) in people with this condition. In 2014, oral substrate reduction therapy (SRT) was approved for type 1 GD treatment. Although both therapies alleviate disease symptoms, effects of SRT on HRQoL and preferences for therapy are not well established. Electronic surveys were administered to adults with type 1 GD. HRQoL was scored with the Short Form36 Version 2 ® Health Survey and descriptive statistics were used to …