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Three Siblings With Familial Non-Medullary Thyroid Carcinoma: A Case Series, Owais Rashid, Naeemul Haque, Saad Farooq, Zareen Kiran,, Sabeeh Siddique, Shahid Pervez
Three Siblings With Familial Non-Medullary Thyroid Carcinoma: A Case Series, Owais Rashid, Naeemul Haque, Saad Farooq, Zareen Kiran,, Sabeeh Siddique, Shahid Pervez
Department of Biological & Biomedical Sciences
Abstract
BACKGROUND:
In 2015, thyroid carcinoma affected approximately 63,000 people in the USA, yet it remains one of the most treatable cancers. It is mainly classified into medullary and non-medullary types. Conventionally, medullary carcinoma was associated with heritability but increasing reports have now begun to associate non-medullary thyroid carcinoma with a genetic predisposition as well. It is important to identify a possible familial association in patients diagnosed with non-medullary thyroid carcinoma because these cancers behave more destructively than would otherwise be expected. Therefore, it is important to aggressively manage such patients and screening of close relatives might be justified. Our …