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Medicine and Health Sciences Commons

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Medical Biophysics

Western University

Western Research Forum

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Full-Text Articles in Medicine and Health Sciences

The Effect Of Sepsis On Cerebral Microvascular Blood Flow, Laura Mawdsley, Mamadou Diop, Chris G. Ellis Mar 2019

The Effect Of Sepsis On Cerebral Microvascular Blood Flow, Laura Mawdsley, Mamadou Diop, Chris G. Ellis

Western Research Forum

Background: Sepsis is a dysregulated host response to infection that affects 18 000 000 people worldwide, and over 325 000 000 dollars are spent treating sepsis in Canada every year. One of the symptoms of severe sepsis is an altered mental state, which is accompanied with a measured decrease in oxygen levels in the skeletal muscle microvasculature. It is hypothesized that his altered mental state is due to a lack of oxygenated blood reaching the brain.

Hypothesis: After the onset of sepsis, microvascular cerebral blood flow and oxygen levels in the blood will decrease. Onset of decreased blood flow in …


P27. Acute Impact Of An Extremely Low Frequency Magnetic Stimulus On Human Neurophysiological Function - Magnetophosphene Perception, Cadence M. Baker Mar 2017

P27. Acute Impact Of An Extremely Low Frequency Magnetic Stimulus On Human Neurophysiological Function - Magnetophosphene Perception, Cadence M. Baker

Western Research Forum

Background: Magnetophosphenes are classified as colourless, flickering lights that are perceived with closed eyes in the dark, and upon exposure to a magnetic field (MF). Uncertainties exist involving the MF threshold for magnetophosphene perception.

Methods: Forty subjects will be enrolled in this experiment aiming to provide a frequency-response curve of magnetophosphene perception under MF exposure. Subjects will sit in a whole head MF exposure device wearing a 64-channel MRI-compatible EEG cap. Subjects will be exposed to a MF with a frequency of 5-300 Hz, in the form of an increasing flux density ramp (increasing magnetic field flux density from 0-100 …