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Full-Text Articles in Medicine and Health Sciences

Selection Of An Eevolved Orthogonal Ne-Acetyllysine Trnasynthetase That Can Incorporate The Unnantural Amino Acid L-Homocitrulline Site-Specifically Into Proteins, Jaclyn Alatrash, Camelia Baleanu Gogonea, Stanly L. Hazen, Joseph Didonato Sep 2014

Selection Of An Eevolved Orthogonal Ne-Acetyllysine Trnasynthetase That Can Incorporate The Unnantural Amino Acid L-Homocitrulline Site-Specifically Into Proteins, Jaclyn Alatrash, Camelia Baleanu Gogonea, Stanly L. Hazen, Joseph Didonato

Undergraduate Research Posters 2014

Oxidatively damaged apolipoprotein A1 (apoA1, the main protein constituent of high density lipoprotein (HDL) - the “good cholesterol”) has been isolated from circulating plasma and atherosclerosis plaque with modification of lysine amino acid residues to homocittruline (carbamyllysine) in apoA1 identified as a modification found increased in smokers that correlates with elevated cardiovascular risk for myocardial infarction (MI), stoke or death. The selected carbamyllysine tRNA synthetase will then be used to express a series of human apoA1 alleles containing amber codons in place of various lysine residues and assayed for its ability to form nascent HDL particles and to activate NF-κB …


"Synthesis Of 4-Aryl-6-Indolylpyridine-3-Carbonitriles And Evaluation Of Their Antiproliferative Activity" Data Files, Naglaa Salem El-Sayed, Amir Nasrolahi Shirazi, Magda Goda El-Meligy, Ahmed Kamel El-Ziaty, Zenat Adeeb Nagib, Keykavous Parang Jan 2014

"Synthesis Of 4-Aryl-6-Indolylpyridine-3-Carbonitriles And Evaluation Of Their Antiproliferative Activity" Data Files, Naglaa Salem El-Sayed, Amir Nasrolahi Shirazi, Magda Goda El-Meligy, Ahmed Kamel El-Ziaty, Zenat Adeeb Nagib, Keykavous Parang

Pharmacy Faculty Data Sets

No abstract provided.