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Full-Text Articles in Medicine and Health Sciences
Epigenetic Dominance Of Prion Conformers, Eri Saijo, Hae-Eun Kang, Jifeng Bian, Kristi G. Bowling, Shawn Browning, Sehun Kim, Nora Hunter, Glenn C. Telling
Epigenetic Dominance Of Prion Conformers, Eri Saijo, Hae-Eun Kang, Jifeng Bian, Kristi G. Bowling, Shawn Browning, Sehun Kim, Nora Hunter, Glenn C. Telling
Microbiology, Immunology, and Molecular Genetics Faculty Publications
Although they share certain biological properties with nucleic acid based infectious agents, prions, the causative agents of invariably fatal, transmissible neurodegenerative disorders such as bovine spongiform encephalopathy, sheep scrapie, and human Creutzfeldt Jakob disease, propagate by conformational templating of host encoded proteins. Once thought to be unique to these diseases, this mechanism is now recognized as a ubiquitous means of information transfer in biological systems, including other protein misfolding disorders such as those causing Alzheimer's and Parkinson's diseases. To address the poorly understood mechanism by which host prion protein (PrP) primary structures interact with distinct prion conformations to influence pathogenesis, …
Comparative Evaluation Of Liquid-Phase Blocking Elisa And Solid-Phase Competition Elisa Methods For The Detection Of Antibodies To The Structural Proteins Of Foot-And-Mouth Disease Types O And A Viruses, Murat Şevi̇k, Fahri̇ Ferudun Öztürk
Comparative Evaluation Of Liquid-Phase Blocking Elisa And Solid-Phase Competition Elisa Methods For The Detection Of Antibodies To The Structural Proteins Of Foot-And-Mouth Disease Types O And A Viruses, Murat Şevi̇k, Fahri̇ Ferudun Öztürk
Turkish Journal of Veterinary & Animal Sciences
In this study, we compared 2 methods, liquid-phase blocking ELISA (LPBE) and solid-phase competition ELISA (SPCE), for the detection of antibodies to the structural proteins of foot-and-mouth disease virus (FMDV). These methods were compared using sera collected from cattle (n = 30) without a history of foot-and-mouth disease infection or vaccination, cattle (n = 180) vaccinated with oil-adjuvanted bivalent vaccine, and international reference sera (positive, weak positive, and negative) for FMDV serotypes O and A. The results showed that SPCE had a better specificity (96.67% for serotype O and 100% for serotype A) than LPBE (90% for serotype O and …
Fertility Issues In Simmental Cows In Central Croatia: A 5-Year Study, Robert Zobel, Suzana Tkalcic, Wendell Cole
Fertility Issues In Simmental Cows In Central Croatia: A 5-Year Study, Robert Zobel, Suzana Tkalcic, Wendell Cole
Turkish Journal of Veterinary & Animal Sciences
The purpose of this study was to establish the fertility trends in dairy cows in Central Croatia and compare the trends and causes of infertility and subfertility during a 5-year period. A total of 12,060 Simmental cows and heifers were included in the study. The animals were examined by vaginoscopy, transrectal palpation, and ultrasonography on a regular basis. Fertility problems that included infertility and subfertility were diagnosed in 56.61% of all observed animals. The total number of animals diagnosed with subfertility increased and almost doubled by the end of the study period. Subfertility issues associated with anovulatory oestrus, delayed ovulation, …
Financial Losses From Foot Diseases In Cattle Farms In Kars Province, Pinar Demi̇r, Sadik Yayla, Özgür Aksoy, İsa Özaydin
Financial Losses From Foot Diseases In Cattle Farms In Kars Province, Pinar Demi̇r, Sadik Yayla, Özgür Aksoy, İsa Özaydin
Turkish Journal of Veterinary & Animal Sciences
This study was performed via a survey conducted of a total of 112 cattle operations in Kars and the vicinity and included a total of 2317 head, of which 280 were determined to have foot problems. The financial loss incurred per operation was calculated in accordance with the data obtained. As a result, the prevalence of foot disease encountered in cattle in the region in 2010 was determined to be 12.08%, and although it varied depending on the severity of the foot diseases, the animals were healed in an average of 46.5 days. Live weights declined by an average of …
Endometritis In Simmental Cows: Incidence, Causes, And Therapy Options, Robert Zobel
Endometritis In Simmental Cows: Incidence, Causes, And Therapy Options, Robert Zobel
Turkish Journal of Veterinary & Animal Sciences
The objectives of this study were to evaluate endometritis incidence and possible causes, and to assess the different therapy options. From a total of 1300 cows, endometritis was diagnosed in 23.07%, with clinical endometritis in 15.31% and subclinical endometritis in 7.77%. Previous dystocia resulted in 40.59% of the clinical endometritis and 47.52% of the subclinical endometritis (P < 0.05). Placental retention caused clinical and subclinical endometritis in 43.18% and 37.50% of the cows, respectively (P < 0.05). Body condition score 2 resulted in the highest endometritis rate and body condition score 3-4 resulted in the lowest endometritis rate (P < 0.05). Corpus luteum was found in 9.67% of the cows suffering from endometritis, while the rest developed various types of subfertility (P < 0.05). Three groups of cows (A, B, and C) with an almost equal number of clinical and subclinical endometritis diagnoses were formed. All of the groups received prostaglandin analogues (PGF Veyx Forte®, Veyx Pharma) intramuscularly 3 times at 11 day intervals. In group A, only prostaglandins were used; in group B, cephapirin (Metricure®, Intervet Schering-Plough) was administered into the corpus uteri simultaneously with the first 2 doses of prostaglandins; and in group C, the first 2 doses of prostaglandins were followed by the ozone product Riger Spray (Novagen, Italy) applied into the uterus. The criteria applied for the therapy success were the number of cows conceived after the first artificial insemination and the number of days open. The best therapy results were achieved in groups C and B (P < 0.05), with the advantage of no milk and meat withdrawing period in the animals of group C.
Localization Of Lactobacillus Plantarum In Bacterial Profile Of Conjunctiva Of Clinically Healthy Cattle, Abdullah Araghi Sooreh, Meisam Baniardalan
Localization Of Lactobacillus Plantarum In Bacterial Profile Of Conjunctiva Of Clinically Healthy Cattle, Abdullah Araghi Sooreh, Meisam Baniardalan
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to determine the normal conjunctival bacterial flora and the effects of sex and age variations on them in healthy cattle in Urmia, Iran. The animals (n = 50) were selected from 2 sexes and divided into 2 age groups. Swabs were taken from the inferior conjunctival sac of both eyes (n = 100) and were cultured on blood and MacConkey agar. All (100%) of the specimens yielded positive bacterial isolations. The bacterial isolates (in order of decreasing frequency) were Lactobacillus plantarum, Escherichia coli, Bacillus cereus, Proteus mirabilis, Enterobacter aerogenes, Staphylococcus epidermidis, and S. aureus. …