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Full-Text Articles in Medicine and Health Sciences
Gm Allotypes And Covid-19. A Pilot Study Performed On Sicilian Patients, Mattia Emanuela Ligotti, Anna Calabrò, Giulia Accardi, Anna Aiello, Calogero Caruso, Claudia Colomba, Danilo Di Bona, Giovanni Duro, Aryan M Namboodiri, Antonino Tuttolomondo, Janardan P Pandey, Giuseppina Candore
Gm Allotypes And Covid-19. A Pilot Study Performed On Sicilian Patients, Mattia Emanuela Ligotti, Anna Calabrò, Giulia Accardi, Anna Aiello, Calogero Caruso, Claudia Colomba, Danilo Di Bona, Giovanni Duro, Aryan M Namboodiri, Antonino Tuttolomondo, Janardan P Pandey, Giuseppina Candore
Translational Medicine @ UniSa
Several studies suggest that genetic variants that influence the onset, maintenance and resolution of the immune response might be fundamental in predicting the evolution of COVID-19. In the present paper, we analysed the distribution of GM allotypes (the genetic markers of immunoglobulin γ chains) in symptomatic and asymptomatic COVID-19 patients and in healthy controls, all born and residing in Sicily. Indeed, the role played by GM allotypes in immune responses and infection control is well known. Our findings show that the GM23 allotype is significantly reduced in healthy controls. Interestingly, in a previous study, Sicilians carrying the GM23 allotype were …
Kl-6 In Ards And Covid-19 Patients, Ornella Piazza, Giuliana Scarpati, Giovanni Boccia, Massimo Boffardi, Pasquale Pagliano
Kl-6 In Ards And Covid-19 Patients, Ornella Piazza, Giuliana Scarpati, Giovanni Boccia, Massimo Boffardi, Pasquale Pagliano
Translational Medicine @ UniSa
The Acute Respiratory Distress Syndrome (ARDS) is a common, devastating clinical pattern characterized by life-threatening respiratory failure. In ARDS there is an uncontrolled inflammatory response that results in alveolar damage, with the exudation of protein-rich pulmonary-edema fluid in the alveolar space. Although severe COVID-19 lung failure (CARDS) often meets diagnostic criteria of traditional ARDS, additional features have been reported, such as delayed onset, binary pulmonary compliant states, and hypercoagulable profile. Increased levels of Krebs von den Lungen 6 (KL-6, also known as MUC1) have been reported in both ARDS and CARDS. KL-6 is a transmembrane protein expressed on the apical …
Kl-6 Levels In Covid-19, Giuliana Scarpati
Kl-6 Levels In Covid-19, Giuliana Scarpati
Translational Medicine @ UniSa
We present preliminary results which encourage KL‐6 evaluation as a potential biomarker for phenotyping COVID-19 patients according to disease severity.
Saving Limited Resources During Covid-19 Pandemic, Ornella Piazza
Saving Limited Resources During Covid-19 Pandemic, Ornella Piazza
Translational Medicine @ UniSa
An epidemic is not only a disease but a social crisis.