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Articles 1 - 19 of 19
Full-Text Articles in Medicine and Health Sciences
Suppression Of F1 Male-Specific Lethality In Caenorhabditis Hybrids By Cbr-Him-8, Vaishnavi Ragavapuram, Emily Elaine King, Scott Everet Baird
Suppression Of F1 Male-Specific Lethality In Caenorhabditis Hybrids By Cbr-Him-8, Vaishnavi Ragavapuram, Emily Elaine King, Scott Everet Baird
Biological Sciences Faculty Publications
Haldane's Rule and Darwin's Corollary to Haldane's Rule are the observations that heterogametic F1 hybrids frequently are less fit than their homogametic siblings and that asymmetric results often are obtained from reciprocal hybrid crosses. In Caenorhabditis, Haldane's Rule and Darwin's Corollary have been observed in several hybrid crosses, including crosses of Caenorhabditis briggsae and Caenorhabditis nigoni. Fertile F1 females are obtained from reciprocal crosses. However, F1 males obtained from C. nigoni mothers are sterile and F1 males obtained from C. briggsae die during embryogenesis. We have identified cbr-him-8 as a recessive maternal-effect suppressor of F1 hybrid male-specific lethality …
Sidestream Smoke Exposure Increases The Susceptibility Of Airway Epithelia To Adenoviral Infection, Priyanka Sharma, Abimbola O. Kolawole, Susan B. Core, Adriana E. Kajon, Katherine J.D.A. Excoffon
Sidestream Smoke Exposure Increases The Susceptibility Of Airway Epithelia To Adenoviral Infection, Priyanka Sharma, Abimbola O. Kolawole, Susan B. Core, Adriana E. Kajon, Katherine J.D.A. Excoffon
Biological Sciences Faculty Publications
Background: Although significant epidemiological evidence indicates that cigarette smoke exposure increases the incidence and severity of viral infection, the molecular mechanisms behind the increased susceptibility of the respiratory tract to viral pathogens are unclear. Adenoviruses are non-enveloped DNA viruses and important causative agents of acute respiratory disease. The Coxsackievirus and adenovirus receptor (CAR) is the primary receptor for many adenoviruses. We hypothesized that cigarette smoke exposure increases epithelial susceptibility to adenovirus infection by increasing the abundance of apical CAR. Methodology and Findings: Cultured human airway epithelial cells (CaLu-3) were used as a model to investigate the effect of sidestream cigarette …
Gene Diversification Of An Emerging Pathogen: A Decade Of Mutation In A Novel Fish Viral Hemorrhagic Septicemia (Vhs) Substrain Since Its First Appearance In The Laurentian Great Lakes, Carol A. Stepien, Lindsey R. Pierce, Douglas W. Leaman, Megan D. Niner, Brian S. Shepherd
Gene Diversification Of An Emerging Pathogen: A Decade Of Mutation In A Novel Fish Viral Hemorrhagic Septicemia (Vhs) Substrain Since Its First Appearance In The Laurentian Great Lakes, Carol A. Stepien, Lindsey R. Pierce, Douglas W. Leaman, Megan D. Niner, Brian S. Shepherd
Biological Sciences Faculty Publications
Viral Hemorrhagic Septicemia virus (VHSv) is an RNA rhabdovirus, which causes one of the world's most serious fish diseases, infecting >80 freshwater and marine species across the Northern Hemisphere. A new, novel, and especially virulent substrain—VHSv-IVb—first appeared in the Laurentian Great Lakes about a decade ago, resulting in massive fish kills. It rapidly spread and has genetically diversified. This study analyzes temporal and spatial mutational patterns of VHSv-IVb across the Great Lakes for the novel non-virion (Nv) gene that is unique to this group of novirhabdoviruses, in relation to its glycoprotein (G), phosphoprotein (P), …
Macroecology Of North American Suckers (Catostomidae): Tests Of Bergmann's And Rapoport's Rules, Stephen J. Jacquemin, Jason C. Doll
Macroecology Of North American Suckers (Catostomidae): Tests Of Bergmann's And Rapoport's Rules, Stephen J. Jacquemin, Jason C. Doll
Biological Sciences Faculty Publications
Discerning spatial macroecological patterns in freshwater fishes has broad implications for community assembly, ecosystem dynamics, management, and conservation. This study explores the potential interspecific covariation of geographic range (Rapoport's rule) and body size (Bergmann's rule) with latitude in North American sucker fishes (Cypriniformes: Catostomidae). While numerous tests of Rapoport's and Bergmann's rules are documented in the literature, comparatively few of these studies have specifically tested for these patterns, and none have incorporated information reflecting shared ancestry into analyses of North American freshwater fish through a hierarchical model. This study utilized a hierarchical modeling approach with Bayesian inference to evaluate the …
Wright State University's Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts From Friday, April 10, 2015, Wright State University Office Of Undergraduate Research And Stemm Activities
Wright State University's Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts From Friday, April 10, 2015, Wright State University Office Of Undergraduate Research And Stemm Activities
Symposium of Student Research, Scholarship, and Creative Activities Materials
The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's fifth annual Celebration of Research, Scholarship and Creative Activities on April 10, 2015.
No Oasis In The Desert: Identification And Implications Of The Food Desert Around An Urban Ohio Hospital, R. J. Sontag
No Oasis In The Desert: Identification And Implications Of The Food Desert Around An Urban Ohio Hospital, R. J. Sontag
Symposium of Student Research, Scholarship, and Creative Activities Materials
Montgomery County, Ohio’s diabetes prevalence outpaces the nation, and the incidence of adult obesity approaches 1/3. Access to healthy food in the impoverished neighborhood surrounding Dayton’s Good Samaritan Hospital, the site of the Family Medicine residency, is important when educating about health lifestyle. The purpose of this project was to determine whether the area was a food desert and to evaluate the implications of the label.
Woodrow Wilson’S Ideological War: American Intervention In Russia, 1918-1920, Shane Hapner
Woodrow Wilson’S Ideological War: American Intervention In Russia, 1918-1920, Shane Hapner
Best Integrated Writing
Shane Hapner analyzes the effects of Woodrow Wilson’s principle of self-determination on American intervention in Russia from 1918-1920 in this essay written for the Integrated Writing course HST 4220: Soviet Union, taught by Dr. Seam Pollock at Wright State University.
Circular Thinking: An Original Analysis Of Lord Of The Flies, John Callon
Circular Thinking: An Original Analysis Of Lord Of The Flies, John Callon
Best Integrated Writing
John Callon examines traits of circular thinking and imagery in William Golding’s Lord of the Flies in this essay written for the Integrated Writing course ENG 4560: Capstone in Integrated Language Arts Curriculum, taught by Dr. Nancy Mack at Wright State University.
Are The Main Institutional Changes That Created The “Business Man” Still Relevant?, Hayden Joblin
Are The Main Institutional Changes That Created The “Business Man” Still Relevant?, Hayden Joblin
Best Integrated Writing
Hayden Joblin examines the forces driving the evolution of the modern business man and whether those still have relevance in this essay written for the Integrated Writing course EC 3190: Institutional Economics, taught by Dr. Hee Young Shin at Wright State University.
Identifying Genes Involved In Suppression Of Tumor Formation In The Planarian Schmidtea Mediterranea, Erin Dorsten
Identifying Genes Involved In Suppression Of Tumor Formation In The Planarian Schmidtea Mediterranea, Erin Dorsten
Best Integrated Writing
Erin Dorsten makes a proposal for a scientific study of experiments to identify genes involved in protecting an organism with negligible senescence from tumor formation in this piece written for the Integrated Writing course BIO 4020: Current Literature: Biology of Regeneration, taught by Labib Rouhana at Wright State University.
The Barb Report, Elizabeth Schoppelrei
The Barb Report, Elizabeth Schoppelrei
Best Integrated Writing
Elizabeth Schoppelrei explores issues of sexuality, kindness, masculinity, discrimination, and respect in this short story written for the Integrated Writing course ENG 4830: Advanced Fiction Writing Seminar, taught by Dr. Erin Flanagan at Wright State University.
How To Recover From The Great Recession And Reduce The Government Debt, Hunter Cregger
How To Recover From The Great Recession And Reduce The Government Debt, Hunter Cregger
Best Integrated Writing
Hunter Cregger proposes how to recover from the Great Recession of the 2000s and reduce government debt in this essay written for the Integrated Writing course EC 2050: Principles of Macroeconomics, taught by Dr. Hee Young Shin at Wright State University.
Inter-Tribal Disunity: An Analysis Of Inter-Tribal Conflict During The Black Hawk War Of 1832, Megan Bailey
Inter-Tribal Disunity: An Analysis Of Inter-Tribal Conflict During The Black Hawk War Of 1832, Megan Bailey
Best Integrated Writing
Megan Bailey explores the effects of inter-tribal disunity and conflict on the Black Hawk War of 1832 in this essay written for the Integrated Writing course HST 3000: Introduction to Historical Analysis, taught by Dr. Noeleen McIlvenna at Wright State University.
Effects Of Caffeine And Vitamin E On Wisconsin Fast Plant, Sarah Ferguson
Effects Of Caffeine And Vitamin E On Wisconsin Fast Plant, Sarah Ferguson
Best Integrated Writing
Sarah Ferguson examines the effects of caffeine and vitamin E on the growth of Wisconsin Fast Plant in this piece written for the Integrated Writing course BIO 3450: Concepts of Biology I for Early and Middle Childhood Education, taught by Mr. Len Kenyon at Wright State University.
Best Integrated Writing 2015 - Complete Edition
Best Integrated Writing 2015 - Complete Edition
Best Integrated Writing
Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University. The journal is published annually by the Wright State University Department of English Language and Literatures.
The Quest For Ash Resistance To Eab: Towards A Mechanistic Understanding, Daniel A. Herms, Don Cipollini, K. S. Knight, J. L. Koch, T. M. Poland, Chad Michael Rigsby, Justin G.A. Whitehill, Pierluigi Bonello
The Quest For Ash Resistance To Eab: Towards A Mechanistic Understanding, Daniel A. Herms, Don Cipollini, K. S. Knight, J. L. Koch, T. M. Poland, Chad Michael Rigsby, Justin G.A. Whitehill, Pierluigi Bonello
Biological Sciences Faculty Publications
Since emerald ash borer (EAB), Agrilus planipennis, was discovered in North America in 2002, it has killed many millions of ash trees in North America, and ash mortality now exceeds 99% near the epicenter of the invasion in southeast Michigan (Klooster et al. 2014). The development of EAB-resistant ash trees will be critical for restoration of ash in natural and urban forests. Goals of our collaboration are to identify, breed and screen ash germplasm for EAB resistance and silvicultural traits; and identify mechanisms of EAB resistance to facilitate breeding and screening.
The Implications Of Hiv Treatment On The Hiv-Malaria Coinfection Dynamics: A Modeling Perspective, F. Nyabadza, B. T. Bekele, Megan A. Rúa, D. M. Malonza, N. Chiduku, M. Kgosimore
The Implications Of Hiv Treatment On The Hiv-Malaria Coinfection Dynamics: A Modeling Perspective, F. Nyabadza, B. T. Bekele, Megan A. Rúa, D. M. Malonza, N. Chiduku, M. Kgosimore
Biological Sciences Faculty Publications
Most hosts harbor multiple pathogens at the same time in disease epidemiology. Multiple pathogens have the potential for interaction resulting in negative impacts on host fitness or alterations in pathogen transmission dynamics. In this paper we develop a mathematical model describing the dynamics of HIV-malaria coinfection. Additionally, we extended our model to examine the role treatment (of malaria and HIV) plays in altering populations’ dynamics. Our model consists of 13 interlinked equations which allow us to explore multiple aspects of HIV-malaria transmission and treatment. We perform qualitative analysis of the model that includes positivity and boundedness of solutions. Furthermore, we …
Characterization Of Calbindin Positive Interneurons Within The Ventral Horn Of The Mouse Spinal Cord, Taylor L. Floyd, David R. Ladle
Characterization Of Calbindin Positive Interneurons Within The Ventral Horn Of The Mouse Spinal Cord, Taylor L. Floyd, David R. Ladle
Symposium of Student Research, Scholarship, and Creative Activities Materials
Sensory-motor circuits in the spinal cord integrate sensory feedback from muscles and modulate locomotor behavior. Although we know how the sensory-motor system generally works, the main issue lies in identifying all neurons involved and understanding their interrelationships. Many interneurons contribute to sensory-motor circuits and have been well studied. For example, Renshaw cells (RC) are inhibitory interneurons that prevent motor neurons from over-activity. A distinguishing feature of RCs is that they are the only interneurons within the ventral-most region of the spinal cord expressing the calcium binding protein calbindin (CB). Recent studies have found other subpopulations of ventral horn interneurons outside …
Expression Of The Nkcc2a Cotransporter In Mouse Central Nervous System, Katherine E. Fahy, James B. Lucot, Hayo Castrop, Mauricio Di Fulvio
Expression Of The Nkcc2a Cotransporter In Mouse Central Nervous System, Katherine E. Fahy, James B. Lucot, Hayo Castrop, Mauricio Di Fulvio
Symposium of Student Research, Scholarship, and Creative Activities Materials
Na-K-2Cl cotransporter 2A (NKCC2A), also known as the bumetanide-sensitive cotransporter 1 (BSC1), transports Na+, K+ and Cl- with a stoichiometry of 1:1:2. NKCC2A is considered a kidney specific cotransporter. It is abundantly expressed in apical membrane of the tubular cells in the thick ascending limb of the loop of Henle (TALH) and in the macula densa. However, NKCC2 has also been found at low levels in different cells, including insulin-secreting ones. This secondary active transporter uses the energy stored in the electrochemical gradients of Na and K maintained by the Na/K-ATPase located on the basolateral membrane of the TALH. The …