Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Medicine and Health Sciences
Hepatitis B Virus Interacts With Albumin Precursor In Vivo, Saeeda Baig, Anwar Ali Siddiqui, Shamim Mushtaq, Jawed Shafqat
Hepatitis B Virus Interacts With Albumin Precursor In Vivo, Saeeda Baig, Anwar Ali Siddiqui, Shamim Mushtaq, Jawed Shafqat
Department of Biological & Biomedical Sciences
A range of proteins has been recognized as mediators/hypothetical receptors for hepatitis B virus (HBV), but the results are conflicting and inconclusive especially regarding their biological significance. This study was aimed at identifying a novel HBV-interacting protein which would provide a better understanding of its transport in blood, attachment, fusion and entry into hepatocytes. Serum samples positive for HBV confirmed by PCR were subjected to ammonium sulfate fractionations at 50, 75, 100%, saturation. PCR of each fraction demonstrated amplification of HBV in 100% fraction. Protein analysis by SDS PAGE of fractions showed one band of approximately 69 kDa protein, in …