Medicine and Health Sciences Commons^™

Individualized Cognitive Rehabilitation For Adults With Acquired Brain Injury, Emily M. Aiken

Masters Theses

Acquired Brain Injury (ABI) can result from internal factors (e.g. tumor) or external causes (e.g. trauma). Three case studies of Korsakoff’s syndrome, meningioma, and traumatic brain injury (TBI), will be presented to illustrate the variety of cognitive deficits across different individuals with ABI. This study uses cognitive rehabilitation therapies to target individual cognitive symptoms. Results and discussion place emphasis on the use of prospective memory (PM) training for treating Korsakoff’s syndrome. The Memory for Intentions Screening Test (MIST) served as the assessment for PM analysis pre and post rehabilitation. The data from this study will be used as a model …

The Relationship Between Axonal Injury, Biomarker Expression And Mechanical Response In A Rodent Head Impact Acceleration Model, Yan Li

Wayne State University Dissertations

In the United States 1.4 million people sustain traumatic brain injury (TBI) each year, resulting in 235,000 hospitalizations and 50,000 fatalities annually. Traumatic axonal injury (TAI) is a serious outcome of TBI that accounts for 40-50% of hospitalizations due to head injury and one third of the mortality due to TBI, and it is difficult to diagnose and evaluate. The purpose of this dissertation is to determine mechanical injury predictors for TAI and identify potential biomarkers to evaluate TAI.

In this dissertation, a modified Marmarou impact acceleration injury model was developed to allow the monitoring of velocity of the impactor …

An Investigation Of The Relationship Between Axonal Injury, Biomarker Expression And Mechanical Response In A Rodent Head Impact Acceleration Model, Yan Li

Wayne State University Dissertations

In the United States 1.4 million people sustain traumatic brain injury (TBI) each year, resulting in 235,000 hospitalizations and 50,000 fatalities annually. Traumatic axonal injury (TAI) is a serious outcome of TBI that accounts for 40-50% of hospitalizations due to head injury and one third of the mortality due to TBI, and it is difficult to diagnose and evaluate. The purpose of this dissertation is to determine mechanical injury predictors for TAI and identify potential biomarkers to evaluate TAI.

In this dissertation, a modified Marmarou impact acceleration injury model was developed to allow the monitoring of velocity of the impactor …