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2019

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Full-Text Articles in Medicine and Health Sciences

Saving Software And Using Emulation To Reproduce Computationally Dependent Research Results, Euan Cochrane, Limor Peer, Ethan Gates, Seth Anderson Dec 2019

Saving Software And Using Emulation To Reproduce Computationally Dependent Research Results, Euan Cochrane, Limor Peer, Ethan Gates, Seth Anderson

Yale Day of Data

Using digital data necessarily involves software. How do institutions think about software in the context of the long-term usability of their data assets? How do they address usability challenges uniquely posed by software such as, license restrictions, legacy software, code rot, and dependencies? These questions are germane to the agenda set forth by the FAIR principles. At Yale University, a team in the Library is looking into the application of a novel approach to emulation as a potential solution. In this presentation, we will outline the work of the Emulation as a Service Infrastructure (EaaSI) program, discuss our plans for …


Combating Intersection-Related Imposter Phenomenon In The Workplace Through Career Readiness, Simone Stewart Nov 2019

Combating Intersection-Related Imposter Phenomenon In The Workplace Through Career Readiness, Simone Stewart

Black Issues Conference

Research has determined that Impostor Phenomenon (IP) most likely occurs in members of minority groups, students, first generation professionals and persons for whom success came quickly. Other studies have shown that many professional women are One of the ways to combat IP is through the development of competencies needed in your career. Attend this workshop to learn how to develop strategies to approach career competency while on campus and throughout your career to keep you on top of your game!


Evaluating Volatile Organic Compounds For Contact-Independent Antagonism Of Pseudogymnoascus Destructans Nov 2019

Evaluating Volatile Organic Compounds For Contact-Independent Antagonism Of Pseudogymnoascus Destructans

Symposium of Student Scholars

White-nose syndrome (WNS), a disease caused by the fungus Pseudogymnoascus destructans, is responsible for the extensive mortality of bats in the United States. In an effort to develop tools to reduce bat mortality attributed to WNS, an in vitro experiment was conducted to quantify the inhibitory effects of select volatile organic compounds (VOCs) as well as explore potential synergistic activities. The experiment involved exposing mycelial plugs of P. destructans to various concentrations of B23 as well as B23 and decanal together at equimolar ratios. Measurements of the plugs were taken over the course of the 13 day experiment allowing …


The Effects Of Caffeine Ingestion On The Hemostatic Response To Simulated Firefighting Activities, Sierra Wassell Nov 2019

The Effects Of Caffeine Ingestion On The Hemostatic Response To Simulated Firefighting Activities, Sierra Wassell

Showcase of Graduate Student Scholarship and Creative Activities

The leading cause of death among firefighters is sudden cardiac event, and it is acknowledged that most ischemic events are due to an occlusive thrombus formation. In addition, due to the demanding job requirements and shift work, firefighters are commonly known to overuse caffeine as an ergogenic aid. The purposes of this study were to examine the potential effects of caffeine on the hemostatic response to simulated firefighting activity.


The Effect Of Oral Contraceptives On Caffeine Metabolism And Cycling Performance, Annette M. Lemanski Nov 2019

The Effect Of Oral Contraceptives On Caffeine Metabolism And Cycling Performance, Annette M. Lemanski

Showcase of Graduate Student Scholarship and Creative Activities

This project objectives were to determine the effects of oral contraceptives and menstrual cycle on the benefits of caffeine supplementation for cycling performance. Seventeen recreationally trained female cyclists completed four trials consisting of 3 kilometer time trials. Subjects ingested either caffeine or a placebo one hour prior to each trial. The magnitude of the ergogenic aid of caffeine was compared between oral contraceptive users and eumenorreheic females. In addition, the effect of caffeine was compared across different phases of the menstrual cycle, specifically the follicular and luteal phases.


Biology Practicum Course, Jose Garcia Oct 2019

Biology Practicum Course, Jose Garcia

Trick to the Treat of Internships and Research

No abstract provided.


Love & Angels Care Internship, Kristin Addison Oct 2019

Love & Angels Care Internship, Kristin Addison

Trick to the Treat of Internships and Research

No abstract provided.


Harbor Branch Oceanographic Institute Summer Intern Program, Nicolas Vitari Oct 2019

Harbor Branch Oceanographic Institute Summer Intern Program, Nicolas Vitari

Trick to the Treat of Internships and Research

No abstract provided.


Md Anderson University Outreach Summer Program, Melanie Fraidenburg Oct 2019

Md Anderson University Outreach Summer Program, Melanie Fraidenburg

Trick to the Treat of Internships and Research

No abstract provided.


Clear Vision Optometry Clinic Internship, Howard Ho Oct 2019

Clear Vision Optometry Clinic Internship, Howard Ho

Trick to the Treat of Internships and Research

No abstract provided.


Medical University Of Graz, Austria Internship, Vanessa Cruise Oct 2019

Medical University Of Graz, Austria Internship, Vanessa Cruise

Trick to the Treat of Internships and Research

No abstract provided.


Clear Vision Optometry Clinic Internship, Taylor Veneza Oct 2019

Clear Vision Optometry Clinic Internship, Taylor Veneza

Trick to the Treat of Internships and Research

No abstract provided.


Atlantis Fellowship - Spain / Italy Summer Internship, Cassidy Campanella Oct 2019

Atlantis Fellowship - Spain / Italy Summer Internship, Cassidy Campanella

Trick to the Treat of Internships and Research

No abstract provided.


University Of Miami Summer Undergraduate Research Fellowship (Surf), Elizabeth Feldman Oct 2019

University Of Miami Summer Undergraduate Research Fellowship (Surf), Elizabeth Feldman

Trick to the Treat of Internships and Research

No abstract provided.


Seminole State College Cure Research Program: From The Classroom To Collaboration, Maya Patrice Byfield Phd Oct 2019

Seminole State College Cure Research Program: From The Classroom To Collaboration, Maya Patrice Byfield Phd

Florida Statewide Symposium: Best Practices in Undergraduate Research

It is believed that if students are taught inductively in their first 2 years, it could induce many of them to seek research experiences later in their academic careers. To do this, we initiated an effort to promote engagement in research topics and faculty development. First, collaboration between one faculty member at SSC and a Principal Investigator at the Sanford-Burnham Institute was developed. This collaboration resulted in the creation of several internships at the Institute for students in the newly developed STEM research class. Second, to increase student engagement, the biology department developed a research focused colloquium series. Each fall …


Mathematics Saves Lives: Models And Signals Enabling Medicine And Biology, Raina Robeva Oct 2019

Mathematics Saves Lives: Models And Signals Enabling Medicine And Biology, Raina Robeva

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Using Empirical And Theoretical Approaches To Control Outbreaks Of An Emerging Disease (Swimmer’S Itch) In The Midwest Of The U.S.A., Gregory J. Sandland, James Peirce Oct 2019

Using Empirical And Theoretical Approaches To Control Outbreaks Of An Emerging Disease (Swimmer’S Itch) In The Midwest Of The U.S.A., Gregory J. Sandland, James Peirce

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Transient Dynamics Of Infection Transmission In An Intensive Care Unit, Christopher Short, Matthew S. Mietchen, Eric T. Lofgren Oct 2019

Transient Dynamics Of Infection Transmission In An Intensive Care Unit, Christopher Short, Matthew S. Mietchen, Eric T. Lofgren

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Oscillation In Mathematical Epidemiology, Meredith Greer Oct 2019

Oscillation In Mathematical Epidemiology, Meredith Greer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Effect Of Promoting Psychosocial Resilience In Adolescents With Diabetes: An Integrative Literature Review, Britney Sandino Aug 2019

Effect Of Promoting Psychosocial Resilience In Adolescents With Diabetes: An Integrative Literature Review, Britney Sandino

Grace Peterson Nursing Research Colloquium

Background: Adolescent obesity and diabetes increase the risk of numerous physiological health threats and psychosocial stress disorders. Educating this population on how to cope with physical and psychosocial stressors improves their health status and health-related quality of life (HRQOL).

Objectives: The purpose of this review was to provide the nursing community with insight on the health promotion effects of fostering psychosocial resilience in diabetic adolescents aged 7 to 17 and suggest specific methods to integrate into their plan of care.

Methods: An integrative literature review was performed using PubMed, Cumulative Index to Nursing and Health Literature, Ovid Medline, ProQuest …


Role Of Gp120 Glycosylation In Sexual Transmission Of Hiv, Yingxue Sun, Adam Meadows, Najwa Zebian, Eric Arts, Carole Creuzenet Jun 2019

Role Of Gp120 Glycosylation In Sexual Transmission Of Hiv, Yingxue Sun, Adam Meadows, Najwa Zebian, Eric Arts, Carole Creuzenet

Western Research Forum

Background:

In chronic HIV patients, the viral populations are genetically diverse due to mutations introduced by the viral reverse transcriptase during HIV replication. However, more than 80% new infections result from single transmission founder (TF) viruses; therefore, targeting the TFs is key to control AIDS worldwide.

Gp120 is a glycosylated envelope protein required for HIV infection, propagation, and transmission. Glycans on gp120 influence HIV infectivity through their interactions with lectins, the carbohydrate-binding immune proteins in the host mucosa. To transmit sexually, viruses must overcome the lectin traps to access more target T cells.

Hypothesis:

TF viruses are less likely to …


An Application Of The Modifiable Areal Unit Problem: Optimizing Cluster Method Parameters To Produce Predictive Data For Hiv Outbreaks, Connor J. Chato, Art Fy Poon Jun 2019

An Application Of The Modifiable Areal Unit Problem: Optimizing Cluster Method Parameters To Produce Predictive Data For Hiv Outbreaks, Connor J. Chato, Art Fy Poon

Western Research Forum

Background

A popular approach to study HIV outbreaks is to cluster cases based on genetic similarity. However, there is no widely-used statistical criterion which optimizes the parameters for sequence-based clustering methods. The relationship between a cluster-defining similarity threshold and it’s associated set of clusters can be analogized to the aggregation level in the Modifiable Areal Unit Problem (MAUP).

Hypothesis

Based on the selection of aggregation level for study partitions in MAUP, we present a statistical framework to optimize the similarity threshold for pairwise distance algorithm TN93 (http://github.com/veg/tn93). We hypothesize that defining this threshold includes case connections such that …


The Wet Bridge Transfer System: An Novel In Vitro Tool For Assessing Exogenous Surfactant As A Pulmonary Drug Delivery Vehicle, Brandon J. Baer Jun 2019

The Wet Bridge Transfer System: An Novel In Vitro Tool For Assessing Exogenous Surfactant As A Pulmonary Drug Delivery Vehicle, Brandon J. Baer

Western Research Forum

Background:

Due to its complex branching structure, direct drug delivery to the remote areas of the lung is a major challenge. Consequently, most therapies, such as those treating pulmonary infection and inflammation, must utilize large systemic dosing, with the potential for adverse side effects. A novel alternative strategy is to use exogenous surfactant, a material capable of distributing throughout the lung, as a pulmonary drug delivery vehicle.

Objective:

Utilize an in vitro transferring system to assess exogenous surfactant (BLES) as a pulmonary delivery vehicle for different therapeutics.

Methods:

An in vitro technique was developed to simultaneously study surfactant delivery and …


Dairy Intake And Cognitive Function In Canadian Older Adults, Mariam R. Ismail Miss, Alan Salmoni Jun 2019

Dairy Intake And Cognitive Function In Canadian Older Adults, Mariam R. Ismail Miss, Alan Salmoni

Western Research Forum

Background: Dietary intake is one of the modifiable factors that may affect older adults’ cognitive function in their later years. Few research has considered the potential role of dairy foods on cognitive function. Methods: Across-sectional study was undertaken in 2014. Cognitive function was assessed using The Montreal Cognitive Assessment (MoCA), Rey Complex Figure Test and Recognition Trial (RCFT), Trail-Making Test (TMT), Victoria Stroop Test (VST) and the Digit Span Test (DST). Dietary intake was assessed via estimated 5-day food intake records and analyzed for saturated fat, vitamin D and calcium. Results: A total of 32 participants (8 males and 24 …


Cell-Free Dna Release During Programmed Cell Death In Ischemia Reperfusion Injury, Alexander Dionne, Anthony M. Jevnikar, Zhu-Xu Zhang Jun 2019

Cell-Free Dna Release During Programmed Cell Death In Ischemia Reperfusion Injury, Alexander Dionne, Anthony M. Jevnikar, Zhu-Xu Zhang

Western Research Forum

Transplantation is invariably associated with acute allograft injury caused by ischemia reperfusion injury (IRI). This injury causes cells of the allograft to undergo various forms of programmed cell death including apoptosis and necroptosis. During programmed cell death, immunogenic molecules are released from cells, one of which is cell-free DNA (cfDNA). We hypothesize that cfDNA is released by microvascular endothelial cells (MVECs) during programmed cell death of IRI and that cfDNA acts as both a biomarker for cellular injury as well as a biologically active molecule capable of amplifying inflammation and organ injury.

Our results indicate that cfDNA is released by …


Predicting Tgf-Β-Induced Epithelial-Mesenchymal Transition Using Data Assimilation, Mario J. Mendez, Matthew J. Hoffman, Elizabeth M. Cherry, Dr. Christopher Lemmon, Seth Weinberg May 2019

Predicting Tgf-Β-Induced Epithelial-Mesenchymal Transition Using Data Assimilation, Mario J. Mendez, Matthew J. Hoffman, Elizabeth M. Cherry, Dr. Christopher Lemmon, Seth Weinberg

Biology and Medicine Through Mathematics Conference

No abstract provided.


Phylogenetic Inference Of Multiscale Selection Pressures Using A Continuous State Birth-Death Process, Marco Hamins-Puertolas, David Rasmussen May 2019

Phylogenetic Inference Of Multiscale Selection Pressures Using A Continuous State Birth-Death Process, Marco Hamins-Puertolas, David Rasmussen

Biology and Medicine Through Mathematics Conference

No abstract provided.


Quantifying Differences In The Interferon Signaling Network Across Cell Types, Sivan Leviyang, Igor Griva, Nate Strawn May 2019

Quantifying Differences In The Interferon Signaling Network Across Cell Types, Sivan Leviyang, Igor Griva, Nate Strawn

Biology and Medicine Through Mathematics Conference

No abstract provided.


Computational Modeling Of Cilia Dynamics In The Human Airways, Uduak George May 2019

Computational Modeling Of Cilia Dynamics In The Human Airways, Uduak George

Biology and Medicine Through Mathematics Conference

No abstract provided.


Characterizing The Permanence And Stationary Distribution For A Family Of Malaria Stochastic Models, Divine Wanduku May 2019

Characterizing The Permanence And Stationary Distribution For A Family Of Malaria Stochastic Models, Divine Wanduku

Biology and Medicine Through Mathematics Conference

No abstract provided.