Medicine and Health Sciences Commons^™

Influence Of Age And Maturation Status On Sprint Acceleration Characteristics In Junior Australian Football, Toby Edwards, Jonathon Weakley, Harry G. Banyard, Ashley Cripps, Benjamin Piggott, G. Gregory Haff, Christopher Joyce

Health Sciences Papers and Journal Articles

This study aimed to investigate the influence of chronological age and maturation status on sprint acceleration characteristics in junior Australian football (AF) players. Biological maturity of 109 subjects was assessed and subjects were grouped according to predicted years from peak height velocity (PHV) (pre-, mid-, and post-PHV) and chronological age (13 years, 14 years, and 15 years). A one-way multivariate analysis of variance and magnitude-based decisions were used to determine between-group differences. Instantaneous velocity was measured during two maximal 30m sprints via radar gun with the velocity-time data used to derive the force, velocity, and power characteristics. Chronologically, the greatest …

Wellbeing And Nature Connectedness For Emerging Adult Undergraduates After A Short Expedition: A Small Pilot Study, Michael J.A Down, Paola Chivers, Prudence Kirsch, Duncan Picknoll

Health Sciences Papers and Journal Articles

Issue addressed: Emerging adult university undergraduates are a vulnerable population due to various life stressors. Previous studies have reported a range of positive outcomes from outdoor expeditions for this population. This small pilot study aimed to investigate the impacts of an outdoor expedition on wellbeing and connectedness to nature and possible confounding by gender and living environment.

Methods: A sample of 54 Health and Physical Education emerging adult undergraduates in the second year of their four-year degree completed a 3-day/2-night immersion expedition. Pre-post differences and a repeated-measures analysis with confounders examined the expedition's impact on scores from the Warwick-Edinburgh Mental …

Operation Of The Basketball Jump Shooting Accuracy Test: Intra- And Inter-Rater Reliability Of Scoring Procedures And Floor And Ceiling Effects For Test Performance, Brenton J. Boddington, Ashley Cripps, Aaron T. Scanlan, Tania Spiteri

Health Sciences Papers and Journal Articles

The purpose of this study was to determine the intra- and inter-rater reliability of scoring procedures used in the newly developed Basketball Jump Shooting Accuracy Test (BJSAT) and assess for floor and ceiling effects in test performance. Thirty-one semi-professional basketball athletes completed four trials of the BJSAT. The BJSAT contains one jump shot at eight different locations, equally distributed across two- and three-point shots. Intra-rater reliability was determined by assessing the level of agreement between scores live in-person and watching captured video by the same assessor. Inter-rater reliability was determined by examining the level of agreement between two assessors who …

Readiness To Train: Return To Baseline Strength And Velocity Following Strength Or Power Training, Alexander Vernon, Christopher Joyce, Harry G. Banyard

Health Sciences Papers and Journal Articles

This study investigated the return to baseline of movement velocity and maximal strength following a strength-orientated session and power-orientated session in the free-weight back-squat performed with maximal concentric velocity. Fourteen strength-trained males completed a strength-orientated session (five sets of five repetitions @80% of a one-repetition maximum) and a power-orientated session (three sets of six repetitions @50% one-repetition maximum ) in a randomised order over two weeks (e.g. strength week 1, power week 2). The back-squat was then performed with loads of 20%, 40%, 60%, 80%, 90% and 100% one-repetition maximum at 24, 48, 72 and 96 h following the strength …

The Well-Being Of Carers Of Older Aboriginal People Living In The Kimberley Region Of Remote Western Australia: Empowerment, Depression, And Carer Burden, Dina Logiudice, Cathryn M. Josif, Roslyn Malay, Zoe Hyde, Melissa Haswell, Melissa A. Lindeman, Christopher Etherton-Beer, David Atkinson, Dawn Bessarab, Leon Flicker, Kate Smith

Health Sciences Papers and Journal Articles

Objective: To describe demographic features and well-being of carers of Aboriginal Australians aged ≥45 years in remote Western Australia.

Method: Carer burden, empowerment, and depression were assessed in 124 Aboriginal carers in four remote Aboriginal communities.

Results: Carers were aged 38.8 ± 15.0 years, 73.4% were female, and 75.8% were children or grandchildren of the person cared for. The mean Zarit-6 score was 3.7 ± 3.6. Attending high school (odds ratio [OR] = 0.3; 95% confidence interval [CI] = [0.1, 0.7]) and feeling empowered (OR = 0.2; 95% CI = [0.1, 0.8]) were inversely associated with carer burden; female carers …

Mesothelial Cells Regulate Immune Responses In Health And Disease: Role For Immunotherapy In Malignant Mesothelioma, Steven E. Mutsaers, Fiona J. Pixley, Cecilia M. PrêLe, Gerard F. Hoyne

Health Sciences Papers and Journal Articles

Highlights:

• Mesothelial and immune cell interactions play a crucial role in tissue homeostasis in the serosal cavities such as the pleura.

• Mesothelin is viewed as an attractive target for solid tumors, including malignant mesothelioma.

• Checkpoint inhibitor therapy has shown variable efficacy against malignant mesothelioma.

• CAR T cell therapies are being evaluated for malignant mesothelioma.

• Treatment of malignant mesothelioma will require multimodality approaches with immunotherapy central to future therapeutic approaches.

The mesothelium when first described was thought to function purely as a non-adhesive surface to facilitate intracoelomic movement of organs. However, the mesothelium is now recognized as a dynamic cellular membrane …

Sprint Acceleration Characteristics Across The Australian Football Participation Pathway, Toby Edwards, Benjamin Piggott, Harry G. Banyard, G Gregory Haff, Christopher Joyce

Health Sciences Papers and Journal Articles

The aim of this study was to compare the force, velocity and power profiles of a maximal sprint acceleration through different competition levels of the Australian Football (AF) participation pathway. One hundred and sixty-two junior AF athletes across five competition levels including State under 18’s (ST 18), State under 16’s (ST 16), local under 18’s (LOC 18), local under 15’s (LOC 15), and local under 14’s (LOC 14) participated in this cross-sectional study. Velocity-time data from maximal sprint accelerations were analysed to derive athlete’s sprint acceleration characteristics and split times. ST 18 showed a more force-orientated profile than the LOC …

Sprint Acceleration Force-Velocity-Power Characteristics In Drafted Vs Non-Drafted Junior Australian Football Players: Preliminary Results, Toby Edwards, Benjamin Piggott, Harry G. Banyard, G. Gregory Haff, Christopher Joyce

Health Sciences Papers and Journal Articles

This investigation aimed to compare the maximal sprint acceleration profiles of drafted and non-drafted elite junior Australian football (AF) players. Nineteen players (10 drafted and 9 non-drafted) from an elite junior AF state team participated in this study. Instantaneous velocity was measured via radar gun during maximal 30 m sprints. The velocity-time data were analysed to derive individual force-velocity-power characteristics and sprint times. No significant differences existed between groups, however drafted players reached moderately faster maximum velocity (Hedges’ g = 0.70 [-0.08; 1.48] and theoretical maximum velocity (g = 0.65 [-0.13; 1.42]) than non-drafted players indicating a superior ability to …

Physical And Energy Demand Of Soccer: A Brief Review, Filippo Dolci, Nicolas H. Hart, Andrew E. Kilding, Paola Chivers, Benjamin Piggott, Tania Spiteri

Health Sciences Papers and Journal Articles

Soccer is a complex and exhaustive team-sport requiring a high level of tactical, technical, and physical ability to succeed. During a competitive match, a random combination of explosive and powerful activities, together with technical and tactical gestures, is performed in an intermittent manner over a 90-minute game. This review presents a detailed analysis and up-to-date synthesis of the literature describing activities and energy system contribution during soccer to provide to strength and conditioning coaches a clear understanding of soccer players’ physical needs during competition.

The Potential Therapeutic Effects Of Creatine Supplementation On Body Composition And Muscle Function In Cancer, C M. Fairman, K L. Kendall, Nicolas H. Hart, D R. Taaffe, D A. Galvao, R U. Newton

Health Sciences Papers and Journal Articles

Low muscle mass in individuals with cancer has a profound impact on quality of life and independence and is associated with greater treatment toxicity and poorer prognosis. Exercise interventions are regularly being investigated as a means to ameliorate treatment-related adverse effects, and nutritional/supplementation strategies to augment adaptations to exercise are highly valuable. Creatine (Cr) is a naturally-occurring substance in the human body that plays a critical role in energy provision during muscle contraction. Given the beneficial effects of Cr supplementation on lean body mass, strength, and physical function in a variety of clinical populations, there is therapeutic potential in individuals …

Genetic Predictors Of Match Performance In Sub-Elite Australian Football Players: A Pilot Study, Ysabel Jacob, Paola Chivers, Ryan S. Anderton

Health Sciences Papers and Journal Articles

The current study aimed to determine whether previously identified candidate polymorphisms were associated with match performance in sub-elite Australian Rules Football (ARF) players. The genotypes of thirty players were analysed along with 3x1-kilometre time trial results, ARF-specific skill assessments (handball and kicking), and match performance (direct game involvements) per minute (DGIs/min) to investigate if there was a relationship between any of the variables. Results support previous findings that aerobic time trials are a significant predictor of DGIs/min in sub-elite ARF players. Significant associations were found for genotypes ADRB2 CC (p = .001), PPARGC1A AA (p = .001), PPARGC1A …

Poly-Arginine Peptide R18d Reduces Neuroinflammation And Functional Deficits Following Traumatic Brain Injury In The Long-Evans Rat, Li Shan Chiu, Ryan S. Anderton, Jane L. Cross, Vince W. Clark, Neville W. Knuckey, Bruno P. Meloni

Health Sciences Papers and Journal Articles

We have previously demonstrated that the poly-arginine peptide R18 can improve histological and functional outcomes following traumatic brain injury (TBI) in the Sprague–Dawley rat. Since D-enantiomer peptides are often exploited in pharmacology for their increased stability and potency, the present study compared the effects of R18 and its D-enantiomer, R18D, following TBI in the Long-Evans rat. Following a closed-head impact delivered via a weight-drop apparatus, peptide was administered at a dose of 1000 nmol/kg at 30 min after TBI. Treatment with R18D, but not R18 resulted in significant reductions in sensorimotor (p = 0.026) and vestibulomotor (p = 0.049) deficits …

Treatment, Prevention And Public Health Management Of Impetigo, Scabies, Crusted Scabies And Fungal Skin Infections In Endemic Populations: A Systematic Review, Philippa J. May, Steven Y.C Tong, Andrew C. Steer, Bart J. Currie, Ross M. Andrews, Jonathan R. Carapetis, Asha C. Bowen

Health Sciences Papers and Journal Articles

We conducted a systematic review of the treatment, prevention and public health control of skin infections including impetigo, scabies, crusted scabies and tinea in resource-limited settings where skin infections are endemic. The aim is to inform strategies, guidelines and research to improve skin health in populations that are inequitably affected by infections of the skin and the downstream consequences of these. The systematic review is reported according to the PRISMA statement. From

1759 titles identified, 81 full text studies were reviewed and key findings outlined for impetigo, scabies, crusted scabies and tinea. Improvements in primary care and public health management …

The Validity And Reliability Of The Basketball Jump Shooting Accuracy Test, Brenton J. Boddington, Ashley Cripps, Aaron T. Scanlan, Tania Spiteri

Health Sciences Papers and Journal Articles

The aim of this study was to examine the content validity, construct validity and reliability of the newly developed Basketball Jump Shooting Accuracy Test (BJSAT). Basketball athletes from different playing levels (State Basketball League [SBL], n = 30, age: 22.7 ± 6.1 yr; SBL Division I, n = 11, age: 20.6 ± 2.1 yr) completed four separate trials of the BJSAT with each trial consisting of shot attempts from two- and three-point distances at pre-determined court locations. Each shot attempt was scored utilising a criteria where higher scores were given when greater accuracy was exhibited. The BJSAT detected a significant, …

Validity Of The Falls Risk For Older People In The Community (Frop‑Com) Tool To Predict Falls And Fall Injuries For Older People Presenting To The Emergency Department After Falling, Marlon Mascarenhas, Keith D. Hill, Anna Barker, Elissa Burton

Health Sciences Papers and Journal Articles

The aims of this study were to (1) externally validate the accuracy of the Falls Risk for Older People in the Community (FROP-Com) falls risk assessment tool in predicting falls and (2) undertake initial validation of the accuracy of the FROPCom to predict injurious falls (requiring medical attention) in people aged ≥ 60 years presenting to emergency departments (EDs) after falling. Two hundred and thirteen participants (mean age = 72.4 years; 59.2% women) were recruited (control group of a randomised controlled trial). A FROP-Com assessment was completed at a home visit within 2 weeks of ED discharge. Data on falls …

In Their Own Words: A Qualitative Study Exploring Influences On The Food Choices Of University Students, Michelle Lambert, Paola Chivers, Fiona Farringdon

Health Sciences Papers and Journal Articles

Issue addressed: University students generally make independent decisions regarding food choices. Current research about knowledge of Australian Dietary Guidelines (ADG), sources of nutrition information and influences on food choices for this group is scarce.

Methods: Qualitative data were collected from gender‐separated focus groups comprising four female (n = 31) and four male (n = 18) to identify: knowledge of ADG; sources of nutrition information; factors that influence food choices; perceived relevant nutrition messages and how best to deliver them.

Results: Gaps in knowledge were identified particularly regarding number of serves and serving size for food groups. Social media was the …

Reducing Early Preterm Birth For 25 Cents A Day, Julie Quinlivan

Health Sciences Papers and Journal Articles

Editorial. No abstract available.

Embedding Of Psycho-Perceptual-Motor Skills Can Improve Athlete Assessment And Training Programs, Sean Müller, Fleur Van Rens, John Brenton, Khaya Morris-Binelli, Benjamin Piggott, Simon M. Rosalie, Matthew Burgin

Health Sciences Papers and Journal Articles

Practitioners in a variety of sports seek unique ways to train athletes to better prepare them for competition. In this position paper, we argue that inclusion of psycho-perceptual-motor skills, from the fields of sport psychology and sport expertise, is crucial, but underutilized in the assessment and training of athletes. First, a brief introduction is provided as to why psycho-perceptual-motor skill is vital for training athletes. Second, examples are discussed relating to key concepts. These include the following: assessment of expertise discriminators such as visual anticipation under pressure contexts, incorporation of sports analytics and performance analysis to aid reflection upon previous …

The Association Between Hysterectomy And Ovarian Cancer Risk: A Population-Based Record-Linkage Study, Suzanne C. Dixon-Suen, Penelope M. Webb, Louise F. Wilson, Karen Tuesley, Louise M. Stewart, Susan J. Jordan

Health Sciences Papers and Journal Articles

Background: Recent studies have called into question the long-held belief that hysterectomy without oophorectomy protects against ovarian cancer. This population-based longitudinal record-linkage study aimed to explore this relationship, overall and by age at hysterectomy, time period, surgery type, and indication for hysterectomy.

Methods: We followed the female adult Western Australian population (837 942 women) across a 27-year period using linked electoral, hospital, births, deaths, and cancer records. Surgery dates were determined from hospital records, and ovarian cancer diagnoses (n¼1640) were ascertained from cancer registry records.We used Cox regression to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the …

Does Exercise Impact Gut Microbiota Composition In Men Receiving Androgen Deprivation Therapy For Prostate Cancer? A Single-Blinded, Two-Armed Randomised Controlled Trial, Robert U. Newton, Claus T. Christophersen, Ciaran M. Fairman, Nicolas H. Hart, Dennis R. Taaffe, David Broadhurst, Amanda Devine, Raphael Chee, Colin I. Tang, Nigel Spry, Daniel A. Galvao

Health Sciences Papers and Journal Articles

Introduction: A potential link exists between prostate cancer (PCa) disease and treatment and increased inflammatory levels from gut dysbiosis. This study aims to examine if exercise favourably alters gut microbiota in men receiving androgen deprivation therapy (ADT) for PCa. Specifically, this study will explore whether: (1) exercise improves the composition of gut microbiota and increases the abundance of bacteria associated with health promotion and (2) whether gut health correlates with favourable inflammatory status, bowel function, continence and nausea among patients participating in the exercise intervention.

Methods and analysis: A single-blinded, two-armed, randomised controlled trial will explore the influence …

Elevated Serum Homocysteine Levels Have Differential Gender-Specific Associations With Motor And Cognitive States In Parkinson’S Disease, Megan C. Bakeberg, Alexa Jefferson, Maddeson Riley, Michelle Byrnes, Soumya Ghosh, Frank L. Mastaglia, Malcom K. Horne, Sarah Mcgregor, Rick Stell, Jade Kenna, Sue Walters, Dana Hince, Ryan S. Anderton

Health Sciences Papers and Journal Articles

Background: Studies attempting to elucidate an association between homocysteine and symptom progression in Parkinson’s disease (PD) have had largely discrepant findings. This study aimed to investigate elevated serum homocysteine levels and symptom progression in a cohort of PD patients.

Methods: Serum homocysteine, folate, and vitamin B12 levels were measured in 205 people with PD and 78 age-matched healthy controls. People with Parkinson’s disease underwent a battery of clinical assessments to evaluate symptom severity, including motor (MDS-UPDRS) and cognitive (ACE-R) assessments. Multivariate generalized linear models were created, controlling for confounding variables, and were used to determine whether serum markers are associated …

The Influence Of Motor Competence On Adolescent Identity Health: A Mixed Method Study, Amanda Timler, Fleur Mcintyre, Caroline Bulsara, Elizabeth Rose, Beth Hands

Health Sciences Papers and Journal Articles

Our identity develops with age, and many impacting factors will determine whether it is healthy or unhealthy. A particularly fragile phase of identity development occurs during adolescence when level of motor competence may be influential, yet is rarely considered.

Purpose: The purpose of this study was to examine male and female adolescent’s perceptions towards their motor competence and identity development. In-depth information was also collected to understand what factors are important towards identity development during adolescence.

Method: An explanatory sequential mixed methods study was used to examine the extent motor competence influenced the health of an adolescent’s identity. …

Morbidity After Surgical Management Of Cervical Cancer In Low And Middle Income Countries: A Systematic Review And Meta-Analysis, Emma R. Allanson, Aime Powell, Max Bulsara, Hong Lim Lee, Lynette Denny, Yee Leung, Paul Cohen

Health Sciences Papers and Journal Articles

Objective: To investigate morbidity for patients after the primary surgical management of cervical cancer in low and middle-income countries (LMIC).

Methods: The Pubmed, Cochrane, the Cochrane Central Register of Controlled Trials, Embase, LILACS and CINAHL were searched for published studies from 1st Jan 2000 to 30th June 2017 reporting outcomes of surgical management of cervical cancer in LMIC. Randomeffects meta-analytical models were used to calculate pooled estimates of surgical complications including blood transfusions, ureteric, bladder, bowel, vascular and nerve injury, fistulae and thromboembolic events. Secondary outcomes included five-year progression free (PFS) and overall survival (OS).

Findings: Data were available …

Clinical Specialty Training In Uk Undergraduate Medical Schools: A Retrospective Observational Study, Hrisheekesh J. Vaidya, Alexander W. Emery, Emma C. Alexander, Angus J. Mcdonnell, Charlotte Burford, Max Bulsara

Health Sciences Papers and Journal Articles

Objectives: To determine if increased exposure to clinical specialties at medical school is associated with increased interest in pursuing that specialty as a career after foundation training.

Design: A retrospective observational study.

Setting: 31 UK medical schools were asked how much time students spend in each of the clinical specialties. We excluded two schools that were solely Graduate Entry, and two schools were excluded for insufficient information.

Main outcome measures: Time spent on clinical placement from UK undergraduate medical schools, and the training destinations of graduates from each school. A general linear model was used to …

Altered Gut Microbiome In Parkinson's Disease And The Influence Of Lipopolysaccharide In A Human Α-Synuclein Over-Expressing Mouse Model, Anastazja M. Gorecki, Leah Preskey, Megan C. Bakeberg, Jade E. Kenna, Christi Gildenhuys, Gabriella Macdougall, Sarah A. Dunlop, Frank L. Mastaglia, P Anthony Akkari, Frank Koengten, Ryan S. Anderton

Health Sciences Papers and Journal Articles

The interaction between the gut microbiota and alpha-synuclein (αSyn) aggregation in Parkinson’s disease (PD) is receiving increasing attention. The objective of this study was to investigate gut microbiota, and effects of an inflammatory lipopolysaccharide (LPS) trigger in a human αSyn over-expressing mouse model of PD (Thy1-αSyn). Stool samples from patients with confirmed PD and Thy1-αSyn mice were analyzed using 16S ribosomal RNA sequencing. Compared to healthy controls, the relative abundance of mucin-degrading Verrucomicrobiae and LPS-producing Gammaproteobacteria were greater in PD patients. In mice, the abundance of Gammaproteobacteria was negligible in both Thy1-αSyn and wild-type (WT) animals, while Verrucomicrobiae were reduced …

Proteomic Analysis Of Cortical Neuronal Cultures Treated With Poly-Arginine Peptide-18 (R18) And Exposed To Glutamic Acid Excitotoxicity, Gabriella Macdougall, Ryan S. Anderton, Frank L. Mastaglia, Neville W. Knuckey, Bruno P. Meloni

Health Sciences Papers and Journal Articles

Poly-arginine peptide-18 (R18) has recently emerged as a highly effective neuroprotective agent in experimental stroke models, and is particularly efficacious in protecting cortical neurons against glutamic acid excitotoxicity. While we have previously demonstrated that R18 can reduce excitotoxicity-induced neuronal calcium influx, other molecular events associated with R18 neuroprotection are yet to investigated. Therefore, in this study we were particularly interested in protein expression changes in R18 treated neurons subjected to excitotoxicity. Proteomic analysis was used to compare protein expression patterns in primary cortical neuronal cultures subjected to: (i) R18-treatment alone (R18); (ii) glutamic acid excitotoxic injury (Glut); (iii) R18-treatment and …

A Randomized Trial Of Prenatal N-3 Fatty Acid Supplementation And Preterm Delivery, Maria Makrides, Karen Best, Lisa Yelland, Andrew Mcphee, Shao Zhou, Julie Quinlivan, Jodie Dodd, Elinor Atkinson, Huda Safa, Jacqueline Van Dam, Gustaaf Dekker, Monika Skubisz, Amanda Anderson, Beth Kean, Anneka Bowman, Carly Mccallum, Kara Cashman, Robert Gibson

Health Sciences Papers and Journal Articles

Background: Previous studies have suggested that maternal supplementation with n−3 long-chain polyunsaturated fatty acids may reduce the incidence of preterm delivery but may also prolong gestation beyond term; however, more data are needed regarding the role of n−3 long-chain polyunsaturated fatty acids in pregnancy.

Methods: We performed a multicenter, double-blind, randomized trial in which women who were pregnant with single or multiple fetuses were assigned to receive either fish-oil capsules that contained 900 mg of n−3 long-chain polyunsaturated fatty acids (n−3 group) or vegetable-oil capsules that contained trace n−3 long-chain polyunsaturated fatty acids (control group) daily, beginning before 20 weeks …

Microglia Are Both A Source And Target Of Extracellular Cyclophilin A, Gurkiran Kaur Flora, Ryan S. Anderton, Bruno P. Meloni, Gilles J. Guillemin, Neville W. Knuckey, Gabriella Macdougall, Vance Matthews, Sherif Boulos

Health Sciences Papers and Journal Articles

Glioblastoma (GBM) are lethal primary brain tumours whose pathogenesis is aided, at least partly, via a pro-tumorigenic microenvironment. This study investigated whether microglia, a cell component of the GBM microenvironment, mediates pro-tumorigenic properties via the action of cyclophilin A (CypA), a potent secretable chemokine and cytoprotectant that signals via the cell surface receptor, CD147. To this end, intracellular and secreted CypA expression was assessed in human primary microglia and BV2 microglial cells treated with the endotoxin, lipopolysaccharide (LPS) and the oxidative stress inducer, LY83583. We report that human primary microglia and BV2 microglia both express CypA and CD147, and that …

How Have Advances In Ct Dosimetry Software Impacted Estimates Of Ct Radiation Dose And Cancer Incidence? A Comparison Of Ct Dosimetry Software: Implications For Past And Future Research, Susannah Maxwell, Richard Fox, Donald Mcrobbie, Max Bulsara, Jenny Doust, Peter O'Leary, John Slavotinek, John Stubbs, Rachael Moorin

Health Sciences Papers and Journal Articles

Objective: Organ radiation dose from a CT scan, calculated by CT dosimetry software, can be combined with cancer risk data to estimate cancer incidence resulting from CT exposure. We aim to determine to what extent the use of improved anatomical representation of the adult human body “phantom” in CT dosimetry software impacts estimates of radiation dose and cancer incidence, to inform comparison of past and future research.

Methods: We collected 20 adult cases for each of three CT protocols (abdomen/pelvis, chest and head) from each of five public hospitals (random sample) (January-April inclusive 2010) and three private clinics (self-report). Organ …

Increased Risk Of Blood Transfusion In Patients With Diabetes Mellitus Sustaining Non-Major Burn Injury, Linda Mai, Katrina Spilsbury, Dale W. Edgar, Aaron Berghuber, Fiona M. Wood

Health Sciences Papers and Journal Articles

Background: Due to the increased mortality and morbidity associated with blood transfusion, identifying modifiable predictors of transfusion are vital to prevent or minimise blood use. We hypothesised that burn patients with diabetes mellitus were more likely to be prescribed a transfusion. These patients tend to have increased age, number of comorbidities, infection risk and need for surgery which are all factors reported previously to be associated with blood use.

Objective: To determine whether patients with diabetes mellitus who have sustained a burn ≤20% total body surface area (TBSA) are at higher risk of receiving red blood cell transfusion compared to …