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Anatomy and Cell Biology Publications
GABAergic transmission; adolescence; cannabis; prefrontal cortex (PFC); psychiatric diseases
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Full-Text Articles in Medicine and Health Sciences
Effects Of Adolescent Thc Exposure On The Prefrontal Gabaergic System: Implications For Schizophrenia-Related Psychopathology., Justine Renard, Walter J Rushlow, Steven R Laviolette
Effects Of Adolescent Thc Exposure On The Prefrontal Gabaergic System: Implications For Schizophrenia-Related Psychopathology., Justine Renard, Walter J Rushlow, Steven R Laviolette
Anatomy and Cell Biology Publications
Marijuana is the most commonly used drug of abuse among adolescents. Considerable clinical evidence supports the hypothesis that adolescent neurodevelopmental exposure to high levels of the principal psychoactive component in marijuana, -delta-9-tetrahydrocanabinol (THC), is associated with a high risk of developing psychiatric diseases, such as schizophrenia later in life. This marijuana-associated risk is believed to be related to increasing levels of THC found within commonly used marijuana strains. Adolescence is a highly vulnerable period for the development of the brain, where the inhibitory GABAergic system plays a pivotal role in the maturation of regulatory control mechanisms in the central nervous …