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Full-Text Articles in Medicine and Health Sciences
Adherence Mechanism Analysis: The Role Of Prsa Gene In Lactobacillus Acidophilus And Other Infectious Microorganisms, Nujuma Moussa
Adherence Mechanism Analysis: The Role Of Prsa Gene In Lactobacillus Acidophilus And Other Infectious Microorganisms, Nujuma Moussa
AUCTUS: The Journal of Undergraduate Research and Creative Scholarship
No abstract provided.
Investigation Into The Role Of Manganese In The Growth Of The Opportunistic Pathogen Streptococcus Sanguinis, Brittany Spivey
Investigation Into The Role Of Manganese In The Growth Of The Opportunistic Pathogen Streptococcus Sanguinis, Brittany Spivey
AUCTUS: The Journal of Undergraduate Research and Creative Scholarship
While Streptococcus sanguinis plays a beneficial role in the oral cavity as a competitor of Streptococcus mutans and Streptococcus sobrinus, the bacteria that produce dental caries, it can cause deadly infective endocarditis if given the opportunity to colonize the vegetations that form over damaged endocardial tissue. Pre-existing heart conditions, surgery, and intravenous drug use predispose individuals to endocarditis. S. sanguinis growth and consequential virulence is significantly impeded by restriction to manganese. This is due to the resulting overwhelming oxidative stress and formation of reactive oxygen species which damage DNA and other cellular components. Manganese is essential for S. sanguinis proteins …