Medicine and Health Sciences Commons^™

The Effects Of 830nm Light On Inflammation In Retinitis Pigmentosa, Krystal Marie Bach

Theses and Dissertations

Purpose: Retinitis Pigmentosa (RP) is an inherited retinal degenerative disease and the most common cause of blindness in developed countries, affecting approximately 1 in 4,000 people. RP is characterized by photoreceptor cell death and recent studies suggest that chronic inflammation may play a key role in the pathogenesis of RP. Currently, there are no known treatments or preventive measures to delay or halt the loss of photoreceptor cells. Photobiomodulation (PBM) by light in the far-red or near-infrared (NIR) range of the light spectrum has been documented to help promote cell survival and reduce inflammation in several disease states. Recent studies …

Effects Of 670 Nm And 830 Nm Light On The Immune Response To Borrelia Burgdorferi, Felice Chen

Theses and Dissertations

ABSTRACT

EFFECTS OF 670 NM AND 830 NM LIGHT ON THE IMMUNE RESPONSE TO BORRELIA BURGDORFERI

by

Felice Chen

The University of Wisconsin-Milwaukee, 2015

Under the Supervision of Dean T. Nardelli, Ph.D. and Janis T. Eells, Ph.D.

Lyme arthritis is a debilitating joint disorder that arises from Lyme disease, which is a result of infection by the spirochete Borrelia burgdorferi. Antibiotics are the traditional treatment for Lyme disease, but chronic arthritis may persist in some patients despite antibiotic treatment. Therefore, other forms of treatment for Lyme arthritis are needed. Photobiomodulation (PBM) using red or near-infrared light, with wavelengths between 630 …