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Full-Text Articles in Medicine and Health Sciences
Cardiovascular Regulation And Effects Of Respiratory Motor Training In Patients With Chronic Spinal Cord Injury., Bonnie Legg Ditterline
Cardiovascular Regulation And Effects Of Respiratory Motor Training In Patients With Chronic Spinal Cord Injury., Bonnie Legg Ditterline
Electronic Theses and Dissertations
This dissertation attempts to discover the mechanisms between cardiovascular and respiratory motor control post spinal cord injury (SCI): in normal, non-injured (NI) persons, cardiovascular regulation is dependent upon respiration, but there is nothing that suggests the mechanism for this relationship post-SCI. Thus we hoped to evaluate various aspects of cardiovascular regulation to further illustrate how this relationship is changed or unchanged by SCI. Chapter I describes the anatomy and physiology of the spine, respiratory system, and cardiovascular system in a NI person, and then describes how the function of these systems is changed by SCI. In addition, we describe therapies …
Mechanisms And Intervention Strategies For Alcohol And Hiv-Antiretroviral Therapy-Induced Liver Injury., Hridgandh Donde
Mechanisms And Intervention Strategies For Alcohol And Hiv-Antiretroviral Therapy-Induced Liver Injury., Hridgandh Donde
Electronic Theses and Dissertations
Chronic alcohol consumption is a leading cause of liver disease and liver-related death worldwide. Alcoholic liver disease includes, hepatic steatosis, steatohepatitis and ultimately fibrosis and cirrhosis. Emerging evidence has established the important role of the “gut-liver” axis in the development of alcoholic liver disease (ALD). Our recent work indicated that chronic alcohol induced perturbations in the gut microbiome and consequent changes in fatty acids have a major impact on the development of intestinal barrier dysfunction and ALD. The aim of this study was to investigate whether treatment with tributyrin - a butyrate prodrug results in protection against ALD in terms …
Glycine Receptor Alpha Subunit (Glyra) Specific Inhibition Contributes To Ganglion Cell Signaling In Mouse Retina., Chi Zhang
Electronic Theses and Dissertations
In the retina, numerous types of neurons are wired together in a highly specific albeit complex pattern. This sophisticated retinal network allows extraction and encoding of more than 20 representations of the visual scene in its output neurons, the retinal ganglion cells (RGCs). Within the inner plexiform layer (IPL) of retina, glycine receptors (GlyRs) are expressed on different cell classes and modulate RGC visual activity to light onset (ON RGCs) and to light offset (OFF RGCs), for example, their temporal precision and gain control. There are four GlyR alpha subunits (GlyRα1-4) with differential expression patterns in IPL. Each mediates spontaneous …
Characterizing The Neuropeptide Pathways Between The Forebrain And The Pons., Ali Al-Magableh
Characterizing The Neuropeptide Pathways Between The Forebrain And The Pons., Ali Al-Magableh
Electronic Theses and Dissertations
Many current health problems including obesity, hypertension, stroke, heart disease, and type 2-diabetes can be attributed to diet. One powerful determinant of food selection is how good or bad a food 'tastes' (e.g. affective value), and is ranked highly by consumers as their top reason for choosing a food (e.g. preference). Learning plays an important role in the establishment and strengthening of food preference and, thus in guiding food choice and calories consumed. The basis of such learning is provided, in part, by limbic system modulation of gustatory neural processing at lower levels in the medulla and pons. I hypothesize …