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Full-Text Articles in Medicine and Health Sciences

Mind The Gap: A White Paper On Maine's Missing Covid-19 Surveillance Data, How They Perpetuate Health Disparities Of Maine's Citizens With Disabilities, And What Can Be Done To Increase Maine's Public Health Data & Service Equity, Michelle Fong Apr 2023

Mind The Gap: A White Paper On Maine's Missing Covid-19 Surveillance Data, How They Perpetuate Health Disparities Of Maine's Citizens With Disabilities, And What Can Be Done To Increase Maine's Public Health Data & Service Equity, Michelle Fong

Student and Trainee Scholarship

A white paper by Michelle Fong, a 2023 NH-ME Leadership Education in Neurodevelopmental and Related Disabilities (LEND) trainee and MPH student at the University of New England. Equitable health data represents all populations and can be linked to their common characteristics. Maine’s COVID-19 data can be disaggregated by gender, race, ethnicity, and age, but not by disability status or type. It is an example of inequity in data collection, or a data gap, that prevents analysis of pandemic health outcomes for Mainers with disabilities.


An Examination Of The Social And Ecological Risk Factors For Lyme Disease Exposure Amon High School Students In Penobscot County, Maine, Willow Throckmorton-Hansford Apr 2023

An Examination Of The Social And Ecological Risk Factors For Lyme Disease Exposure Amon High School Students In Penobscot County, Maine, Willow Throckmorton-Hansford

Honors College

The intertwining effects of biological and social factors recently have led to a dramatic increase in Lyme disease cases in Maine. These factors include environmental exposure to ticks, a lack of knowledge of prevention measures against ticks, and an increasing population of blacklegged ticks throughout the state. High school students have seldom been used as a group of interest involving Lyme disease prevention research, yet they may be exposed to ticks while engaging in extracurricular activities, outdoor recreation, and in-class lessons that occur outdoors. In addition, social and ecological factors contributing to this issue have never been investigated in tandem …


Evaluating Edna Metabarcoding As A Mic-Roe-Scopic Net To Catch Salmon Pathogens, Noah Burby Apr 2023

Evaluating Edna Metabarcoding As A Mic-Roe-Scopic Net To Catch Salmon Pathogens, Noah Burby

Honors College

Wild Atlantic salmon in the Gulf of Maine (GOM) is a Distinct Population Segment (DPS) that has been listed since 2000 as endangered by the U.S. Fish and Wildlife Service (USFWS) and the National Oceanic and Atmospheric Administration (NOAA). The current challenge is year-over-year decreases in the number of mature salmon returning to the Penobscot River for reproduction. Early detection of pathogen presence could allow for the identification of infection and the application of corrective measures. Environmental DNA (eDNA) is simply DNA that is collected from environmental samples (e.g., water, air, and soils), which consists of whole microorganisms and genetic …


Characterization Of Manganese-Induced Neurodegenration In C. Elegans Treated With Winterberry Leaf Extract, Brendan Moline Apr 2023

Characterization Of Manganese-Induced Neurodegenration In C. Elegans Treated With Winterberry Leaf Extract, Brendan Moline

Honors College

Neurodegeneration is a condition present in Alzheimer’s disease (AD) and Parkinson’s disease (PD) in which the cells of the nervous system experience loss of function and death. Around the world, each year PD and AD affect 6.2 million and 29.8 million people, respectively, with the exact causes remaining unknown. Manganese (Mn) is a transition metal which is essential for human survival in trace concentrations. However, overexposure to Mn can induce neurodegeneration through the accumulation of reactive oxygen species and the eventual onset of oxidative stress. An extract produced from winterberry leaves (Ilex verticillata) exhibits antioxidant properties as it has been …


Comprehensive Overview Of Causative Agents Of Alzheimer's Disease: Tau Protein And Amyloid Betas With Their Biochemical Pathways And Proposed Treatments Including Cost Analysis, Ethan Johnson Apr 2023

Comprehensive Overview Of Causative Agents Of Alzheimer's Disease: Tau Protein And Amyloid Betas With Their Biochemical Pathways And Proposed Treatments Including Cost Analysis, Ethan Johnson

Honors College

Alzheimer’s is a neurodegenerative disease found within the brain, interfering with neuron function, eventually leading to widespread atrophy. The disease effects millions of Americans with neurofibrillary tangles and amyloid beta plaques, both protein deposits with unclear causes. The goal for this thesis was not only to understand how these proteins form but how to safely interfere with their production. This was completed by a comprehensive overview of the form of the buildups and their precursors, tau proteins and amyloid beta precursor protein, respectively. An emphasis was put on the molecular biology and genetic causes of the amyloids rather than the …