Pilot Study: Effects Of Whole Body Vibrational Therapy On Equine Epaxial Muscle Soreness, Riley Leibeck

Undergraduate Honors Thesis Projects

Whole body vibrational therapy (WBV) is well-studied in people, but there is a paucity of research of its effect on horses. It is suggested that WBV use in horses increases performance, aids in recovery, and stimulates nerves, bones, and muscles in ways that normal exercise does not. The purpose of this pilot study was to determine if frequent WBV therapy sessions affect back soreness in horses using pressure algometry. Most sporthorses will experience back soreness in their careers, and it is regarded as one of the most common causes of poor performance in equine athletes. Five horses were measured for …

Mir125a As Molecular Target Of Vitamin D Mediated Inhibition Of Cd4+ T Cell Differentiation Into Th17 Cells In Mrl/Lpr Lupus-Prone Mice, Miranda Hilt

Undergraduate Distinction Papers

The dynamic function of vitamin D in an array of immunomodulatory and anti-inflammatory mechanisms and its implication in the pathogenesis of autoimmune diseases has been the topic of much recent scholarship. Here I attempt to elucidate the molecular mechanism of vitamin D-mediated inhibition of the differentiation of CD4+ T cells into pro-inflammatory Th17 cells in MRL/lpr lupus prone mice by investigating how miR-125a expression is affected by dietary modulation of cholecalciferol (vitamin D₃). MRL/MpJ and MRL/lpr mice were split into three experimental groups and fed specially formulated diets that varied in their concentrations of vitamin D. …

Antibacterial Activity, Structure-Activity Relationships, And Scale-Up Reaction Of 1,3,4-Oxadiazoles, Olivia Marie Smith

Undergraduate Honors Thesis Projects

Oxadiazoles are compounds in the field of organic chemistry that have been gathering interest in the medicinal chemistry and microbiology communities for their biological properties, which range from anti-inflammatory agents, to chemotherapy drugs, to antibiotics. The synthesis of oxadiazoles can be difficult due to the expensive and complex nature of the techniques used as well as the volatile reagents and elevated temperatures that are often required in organic synthesis. The Grote lab has recently developed a new method for the synthesis of 1,3,4-oxadiazoles under mild conditions. The goals of this thesis were thus twofold: to develop a viable scale-up procedure …

Coccidioidomycosis (Valley Fever) Awareness, Kelly Dzialowski

Nursing Student Class Projects (Formerly MSN)

The overall purpose of this poster is to describe the fungal infection, Coccidioidomycosis, and bring awareness to this infection. The poster describes the history of the infection, pathophysiology, risk factors, and clinical presentation. Diagnosis, treatment, and complications of coccidioidomycosis are also addressed. The poster discusses the implications for nursing practice, information about the search for a vaccine, and comparisons of coccidioidomycosis and Covid-19. Finally, the conclusion discusses the key points within the poster and the importance of prompt and accurate diagnosis.

American Virtual Institute: The Covid Practicum, Mitchell Stotler

Masters Theses/Capstone Projects

The American Virtual Institute: The COVID Practicum is a practicum experience focused on presenting to Hungarians and other international attendees about American wellness, leadership, and lifestyle. This practicum experience was completed entirely online via Zoom, Google Meets, and Facebook Live over the 2020-2021 academic year.

Equine Massage Following Intense Work: Effects On Plasma Creatine Kinase, Brittany Pilat

Undergraduate Honors Thesis Projects

Horses are elite athletes, and many of them receive specialized care to keep them operating at their highest potential. Alternative modalities of healing- such as equine massage- have begun to grow in the equine world due to many perceived benefits. Equine massage is thought to decrease inflammation and reduce muscle tension and soreness. The aim of this study was to observe the effect of equine massage on creatine kinase (CK) levels in the blood following intense work. A total of 12 horses were randomly assigned to either the control group (n=6) or the test group (n=6). All horses were exercised …

Determining Age-Related Visual Memory And Line Length Perception In Children And Adults, Katie Exline

Undergraduate Honors Thesis Projects

There is little research in the field of visual memory and perceptual abilities of children as compared to adults. This thesis seeks to understand and provide new perspectives to this field with potential implications in the fields of optometry and education. Through two basic experiments, this thesis evaluates the abilities of individuals to perceive a visual stimulus and compare it other visual stimuli, while also observing their abilities to learn and remember various visual stimuli. Through experimentation using line length as the visual stimulus, the method of constant stimuli (MCS) evaluates subjects’ visual perception and the method of single stimuli …

Environmental Factors' Effects On Eastern Gray Squirrel (Sciurus Carolinensis) Infant Populations And Health, Jenny Mcfarland

Undergraduate Honors Thesis Projects

Ecosystem factors, both biotic and abiotic, impact all animal species. Temperature, rainfall, daylight, windspeed, mast production, competition and predation are integral to the ecosystem and thus affect the survival and overall wellbeing of the population. Eastern gray squirrel (Sciurus carolinensis) infant intakes at Ohio Wildlife Center followed a pattern of more infants in the fall than in the spring, differing from the usual observation that more infants are born in the spring. Ecosystem factors were compared to monthly and annual intakes to see what influenced intake date, admittance condition and survivability rate of the Eastern gray squirrel infants. The results …

Prediction Factors For Release Of Wildlife At A Midwestern Rehabilitation Facility, Abigail E. Smith

Undergraduate Honors Thesis Projects

Wildlife rehabilitation is a large and internationally known field with thousands of rehabilitators around the world. Resources, such as time and money, are extremely limited in rehabilitation facilities and not all animals are candidates for release due to injuries or illnesses that make them unlikely to survive in the wild. Understanding what factors predict release would be useful in focusing limited resources, but there has been little investigation previously. The purpose of this study is to determine what factors affect the survival of mammals and birds at an American Midwest wildlife rehabilitation center. It was found that animals admitted with …

The Pathophysiological Process Of Sepsis, Stefane Adams

Nursing Student Class Projects (Formerly MSN)

Sepsis is a medical emergency and can be a life-threatening illness that results as a complication from a severe infection, which occurs when chemicals that have been released into the bloodstream by the body’s defense system work to fight off an infection (Mayo Clinic, 2016). Sepsis is one of the leading causes of deaths in patients in the hospital setting worldwide, becoming more common than breast and bowel cancer combined (Nursing Times, 2014). Sepsis can affect anyone; however it is more common in the elderly or in individuals with weaker immune systems. Health care providers (HCPs) must fully understand this …

Cross-Sectional Analysis Of Salivary Cortisol And Cyathostome Infestation In Horses, Danielle L. Keating

Undergraduate Honors Thesis Projects

With an increase in anthelmintic resistance and decreased efficacy of many commercial dewormers, understanding factors that contribute to parasite infestations in horses is integral to their management. The goal of this study was to look at the potential relationship between parasites and stress response by evaluating salivary cortisol levels and cyathostome egg shedding levels. Using a sample size of n = 200 horses from the state of Ohio, fecal and saliva samples were collected from each horse. Fecal egg counts were performed for each horse with a modified Stoll method, and saliva samples were tested with an enzyme-linked immunosorbent assay …

The Effect Of Red Maple Leaf Toxicosis On Reduced Glutathione Levels In Equine Erythrocytes In Vitro, Madeline A. Rohl

Undergraduate Honors Thesis Projects

Red maple leaf toxicosis is an equine blood disorder resulting from the consumption of wilted red maple (Acer rubrum L.) leaves by horses. Compounds within the leaves of red maple have oxidative effects on equine erythrocytes and can cause hemolysis of erythrocytes, the conversion of hemoglobin to methemoglobin, and the production of Heinz bodies. Reduced glutathione is important in the protection of equine erythrocytes from these oxidative events; however, in the presence of red maple toxin, glutathione is rapidly oxidized and is unavailable. The objective of this study is to determine whether the presence of vitamin C alters levels …