Medicine and Health Sciences Commons^™

Peak Aerobic Capacity And Dietary Composition Are Associated With The Bioenergetic Profile Of Platelets In Children, Duncan C. Troup

Scholars Day Conference

Atherosclerosis is a disease of the cardiovascular system that is characterized by the buildup of plaque inside arteries over several decades. These plaques have the potential to rupture, causing a clot to form in the vessel. This results in an acute cardiovascular event such as myocardial infarction or stroke. Atherosclerosis remains a significant public health challenge in developed countries, being the foundational cause of roughly 50% of deaths in westernized societies and a major contributor to health costs [13,14]. Understanding this devastating disease and developing preventative measures is a highly important area of research. While the impact of cardiovascular disease …

Developing Zntpp-4ab As A Potential Photodynamic Therapy Agent, Kennedy Johnson

Scholars Day Conference

Photodynamic therapy is a fairly new technique used in cancer treatment involving the use of a photosensitizer and light exposure to kill malignant cells. In this research, the use of ZnTPP-4AB as a photosensitizer and red light as a source of radiant light energy was explored in terms of cytotoxicity in the A549 lung cancer cell line. ZnTPP-4AB was synthesized by replacing the carbonyl functional groups on the ZnTPPC porphyrin with 4-amino-1-butanol. Following synthesis, the new porphyrin was purified through the use of Sephadex LH-20 and G-50 in column chromatography in order to remove impurities. To confirm the identity and …

Assessing The Nutrition Knowledge Of Track And Cross Country Athletes, Emma Kathleen Conner

Scholars Day Conference

Research shows that 76% of athletes arrive at practice and/or games already one percent dehydrated.1 Furthermore, roughly 84% of athletes have engaged in disordered eating patterns and as 70% of female athletes have been found to be falling short in their energy needs. These statistics show the importance of exposing athletes to appropriate sport nutrition education which allows athletes the opportunity to fuel their bodies well, prevent injuries, and improve performance. Additionally Ouachita does not have a sports nutrition registered dietitian on campus to be used as a resource. Due to these statistics, there is reason to believe athletes are …

The Development Of A New Water-Soluble Zinc Porphyrin, Zntpp-2mp, As A Photodynamic Therapy Agent, Emily Payne

Scholars Day Conference

Photodynamic therapy is a new technique used in cancer treatment involving the use of a photosensitizer and light exposure to kill malignant cells. This research tested the use of ZnTPP-2MP as a photosensitizer using white light as a source of possible treatment of the A549 cancer cell line, with preliminary testing on MYC-22 and other G- quadruplex DNA samples. ZnTPP-2MP was synthesized by the reaction of the porphyrin, ZnTPPC, with 2-amino-2- methyl-1-propanol. Following synthesis, the new porphyrin was purified by column chromatography using Sephadex LH-20 and G-50. To confirm the identity and structure of the product, ZnTPP-2MP was analyzed through …

Using Oncodb's Oncovirus Analysis For Hbv-Related Hcc, Anna Claire Newman

Scholars Day Conference

Since one of the known causes of cancer is virus infection causing changes in gene regulation, being able to compare the expression and methylation of regular tumors and virus-related tumors could provide much needed information into virus induced cancer such as HBV-related HCC. OncoDB's oncovirus analysis capabilities can provide information and research opportunities that past research has not had.

The Mental Health And Developmental Effects Of Bisphenol-A, Maryann Rettig

Scholars Day Conference

My directed study focuses on the mental health and developmental effects of bisphenol-A (BPA) on individuals in close contact with the chemical product. BPA is an organic chemical produced in large quantities that is used in the production of many polycarbonate plastics, feminine hygiene products, and epoxy resins that coat some metal food cans. Because of it being everywhere, BPA often leaches dermally and orally into the human body. The physical effects of BPA have been known and observed for years. However, its mental health effects specifically are not as commonly known. Therefore, in my directed study I would be …

Assessment Of Undergraduate Students' Knowledge And Consumption Of Electrolytes And Hydration, Emma Starkman, Emma Starkman

Scholars Day Conference

The purpose of this research was to determine the knowledge that undergraduate students have regarding electrolytes and hydration and assess where further dissemination of knowledge is needed. Considering the essential nature of water and electrolytes and the limited research in this specific subject, the knowledge and consumption thereof by college students was deemed a needed area of assessment.

Sensory Evaluation Of Sugar Substitutes In Peanut Butter Cookies, Emma Starkman

Scholars Day Conference

The purpose of this experiment was to observe and record the differences in visual, sensory, and flavor characteristics of peanut butter cookies baked with different sugar substitutes to determine if a good alternative exists.

Zntppea As A Potential Photosensitizer In Photodynamic Therapy, Marly Welborn, Joseph E. Bradshaw

Scholars Day Conference

Photodynamic therapy (PDT) is an emerging treatment that is used against certain types of cancer and other diseases. It functions using a photosensitizer in the presence of light that contributes to cell death in the desired tissues. This research centered on the development of a novel water-soluble porphyrin that could be utilized as a photosensitizer. Using ethanolamine the resulting compound, ZnTPP-EA, was created. Purification and characterization was carried out. The ZnTPP-EA was tested on the A549 lung cancer cell line using an MTT assay under light and dark conditions to assess the compound's effectiveness as a photosensitizer for PDT.

Effects Of Storage Conditions On Bpa Leanching From Infant Oral Hygiene Products Using Fluorescence Spectroscopy, Emma Bynum, Sara Hubbard

Scholars Day Conference

Bisphenol-A (BPA) is a structural component in many plastic products, which acts as an endocrine-disruptor mimicking estrogen. This hormonal disruption has been linked to obesity, reproductive issues, cardiovascular problems, and neurodevelopment disorders. Infants are at the highest risk of BPA exposure compared to any other stage of life. Because an infant's endocrine system is developing, exposure to an endocrine-disruptor, such as BPA, can be especially harmful. While the FDA monitors products like baby bottles, canned goods, and plastic containers for BPA, infant oral hygiene products are not closely monitored.

Previous research in our lab used fluorescence spectroscopy to test several …

Role Of Nutrition Focused Physical Exam In The Identification Of Malnutrition In The Elderly, Madeline Wallace, Markie Campbell, Detri Brech

Scholars Day Conference

Sixteen percent of the U.S. population is over 65 years of age and up to one out of two have malnutrition. The nutrition-focused physical exam (NFPE) is an integral part of the nutrition care process and model consisting of consecutive steps: nutrition assessment, diagnosis, intervention, and monitoring/evaluation. The NFPE is a component of nutrition assessment providing registered dietitian nutritionists (RDN) with information to determine nutrition status and degree of malnutrition. Six clinical characteristics used to identify malnutrition are energy intake, weight loss, subcutaneous fat loss, muscle loss, fluid accumulation, and reduced function status. Each has a threshold for identification of …

Effects Of Nutrition And Physical Activity Intervention In Improving Children's Bmi-For-Age Percentiles, Markie Campbell, Madeline Wallace, Detri Brech

Scholars Day Conference

According to the World Health Organization (WHO), globally 340 million school-aged children are obese. The Centers for Disease Control and Prevention (CDC) report that 13.7 million (19%) of U.S. children and adolescents age 2-19 years are obese. Obesity rates are 14% in 2- to 5-year-olds, 18% in 6- to 11-year-olds, and 21% in 12- to 19-year-olds. Hispanic children (26%) and non-Hispanic black children (22%) have higher obesity prevalence than non-Hispanic white children (14%). Non-Hispanic Asian children (11%) have lower obesity rates than non-Hispanic black children and Hispanic children. In Arkansas, 22% of school-aged children are obese and 39% are overweight …

Acl Prevention Programs And Its Effectiveness In Reducing The Rate Of Injury In The College Athlete, Dan Kaplun, Anastasiia Ulinova

Scholars Day Conference

A knee injury to the anterior cruciate ligament (ACL) is a common injury among athletes, despite growing knowledge of common injury mechanisms. The athletes with the highest risk of injuring their ACLs are those playing sports that require extreme cutting or pivoting with a sudden change in speed. ACL injuries are most commonly caused by a non-contact process, usually in conjunction with a sudden change of direction or speed. Females are 4-6 times more likely than males to injure their ACL. It is predicted that within a span of one year, 10,000 female college athletes will damage their knee and …