Medicine and Health Sciences Commons^™

Liquid Chromatography With Tandem Mass Spectrometry Method Development For The Determination Of Β–Defensins In Bovine Milk, Symone T. Whalin

Masters Theses & Specialist Projects

Bovine mastitis, caused by a wide array of pathogens, results in a substantial economic loss for the dairy cattle livestock industry. β-defensins are a part of the bovine’s innate immune system and act as the first line of defense against mastitis. Only foundational research has been done on β-defensins’ ability to treat and prevent mastitis. There have been no analytical methods reported in the literature for analyzing β-defensins in bovine milk. This research aims to create an analytical approach to determine β-defensins in bovine milk. It is challenging to determine an analyte in a complex sample matrix, and milk is …

Ua12/2/1 Up Next On The Hill, Vol. 97, No. 6, Wku Student Affairs

WKU Archives Records

Magazine edition of the College Heights Herald for the period Feb. 14 to March 21, 2022.

• Collins, Michael. I Went to School There? University Plan Marks New Era of Campus for Next Generation of Students
• Trickett-Wile, Arthur & Jake Jones. Like Farmer, Like Son – Alex Burke
• Stover, D.J. Gun Violence Hasn’t Left, from a Survivor of Marshall County
• Lanuzza, Izzy. International Bonds Key to WKU Tennis Success

Comparison Of Effects Of Sleep Fragmentation On Pro-Inflammatory Cytokine Il-1Β Of Male And Female Adult Mice, Manzar Rzayeva

Mahurin Honors College Capstone Experience/Thesis Projects

Sleep plays an essential role throughout the body by affecting the physiological function and regulation of many systems. One of these systems that receives effects as a result of the adequacy of sleep is the immune system. Previous studies have demonstrated effects of sleep fragmentation upon the immune system; however, sexual differences of these effects have not been studied in depth. To analyze these variances amongst the genders, male and female adult mice were subjected to acute sleep fragmentation (SF) for 24 hours in an automated SF cage that includes a bar sweeping across the cage every two minutes. Meanwhile, …

Inflammatory Response To Sleep Fragmentation In Skeletal, Cardiac, And Smooth Muscle Tissues In Female Mice, Patton Allen

Mahurin Honors College Capstone Experience/Thesis Projects

Sleep is a critical process that the body undergoes. When sleep is interrupted, so that an individual is awakened for some period before going back into sleep, the sleep can be described as fragmented. Studies in the past have shown that sleep fragmentation (SF) promotes an inflammatory environment, especially in the brain and peripheral tissue. However, studies have not been conducted to observe inflammatory responses in muscle. To examine this, C57BL/6J female mice were subjected to either a control group (no SF) or a SF group which involved using an automated SF chamber to disrupt sleep every 2 min over …

Rurality And Its Effects On Prenatal Care In Southcentral Kentucky, Kylee Eilers

Mahurin Honors College Capstone Experience/Thesis Projects

Despite ongoing efforts to increase positive healthcare outcomes for prenatal care in rural Kentucky, there continues to be limited access to adequate and quality resources. Research questions for this research project explored the prenatal care resources for Allen, Barren, Butler, Edmonson, Hart, Logan, Metcalfe, Monroe, Simpson, and Warren counties, compared healthcare disparities that exist in those counties with other rural regions of Kentucky, and identified limitations of such prenatal care resources in successfully achieving positive care outcomes. In addition to evaluation of applicable online resources through organizations local to the region, some healthcare professional and representatives were interviewed to find …