Medicine and Health Sciences Commons^™

Nanoparticle Conjugated Photosensitizer For Targeted Photodynamic Inactivation Of Cancer Cells, Symone D. Crowder

Honors College Theses

Photodynamic therapy (PDT) is considered to be a potential replacement for traditional methods of chemotherapy. It includes the administration of photosensitizing agents (PS), which generate reactive oxygen species (ROS) upon excitation at a specific wavelength. With new outlooks and techniques, cancer research is advancing each day. It has allowed the progress of several theranostic drug delivery systems (DDS) exploring the area of nanomedicine.2 In the present work, a Rhodamine derivative, Rhodamine 6G (R6G) was used as the PS. In general, rhodamine compounds undergo cytotoxic reactions on photoexcitation by electron transfer reactions with folic acid within cells, making them a favorable …

Synthesis Of Trifluoromethyl Ketones By (Diethylamino) Sulfur Trifluoride (Dast)-Mediated Nucleophilic Trifluoromethylation Of Benzoic Acids, Michael A. Vescio

Honors College Theses

Within the past few decades, the presence of fluorine containing

organic molecules has increased significantly. Many of the

current industrial production methods are not cost-effective,

practical, or inherently safe. This work describes a new methodology

for the synthesis of trifluoromethyl ketones. Our new method involves

the use of benzoic acid and trifluoromethyl trimethylsilane (TMSCF₃) as starting

materials along with diethylamino sulfur trifluoride (DAST) as a reagent

to obtain moderate to good yields of expected products in a short

reaction times.

The Use Of Silica Nanoparticles For Controlled Drug Delivery Of Nicotine, Jennifer C. Iwenofu

Honors College Theses

Drug molecules can be administered in different ways to the human body. Nanotechnology stands out over other alternatives by delivering drugs to specific locations and reducing reactivity time. In this research, the hydrogen bond between silica nanoparticles and the drug molecule, nicotine, were studied to controllably deliver nicotine by varying pH values.

Skin Pigmentation And Arterial Stiffness In Young Health Black And White Adults, Zoe R. Lincoln

Honors College Theses

Cardiovascular disease (CVD) is currently the leading cause of death worldwide, killing over half a million people in the US every year. This issue is only becoming more prominent, as both the world and US population are experiencing increased rates of CVD risk factors such as hypertension, type 2 diabetes, and obesity. Black Americans specifically are experiencing increased rates of these risk factors, possibly due to lifestyle, socioeconomic, and genetic variables, ultimately leading to a higher prevalence of CVD in this population. One possible mechanism for this health disparity is racial differences in skin pigmentation, which can influence cardioprotective Vitamin …

Stress, Stress Appraisal And Coping In Athletic Trainers During The Covid-19 Pandemic, Lawson Holton

Electronic Theses and Dissertations

Introduction: There have been many studies conducted on the stress and mental health of frontline healthcare workers (HCWs) over the past months since the COVID-19 pandemic began. Very limited literature has examined the effect of the pandemic on athletic trainers (ATs). Objective: The aim of this investigation was to examine the stress, stress appraisal, and coping measures of ATs during the COVID-19 pandemic. Methods: Participants were recruited members from the National Athletic Trainers’ Association (NATA). The Perceived Stress Scale-10 was used to measure stress, the Stress Appraisal Measure was used to measure stress appraisal, and the Brief COPE was used …

Effects Of Various Golf Bag Loading Strategies On Perceived Exertion And Vertical Jump Performance, Austen Arnold

Electronic Theses and Dissertations

INTRODUCTION: The sport of golf is increasing in popularity among both novice and skilled players alike. A round of golf necessitates players to cope with a range of physically demanding movement patterns. At the collegiate level, golfers must transport their clubs by loading them onto the body. Previous literature has yet to determine how different golf bag carrying positions influence periodic, unloaded jump performance and perceived exertion of the load carrying task. PURPOSE: The purpose of this study is to investigate how different golf bag load carriage methods may influence vertical jump performance and perceived exertion. METHODS: Five golf bag …