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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Investigative Techniques

Old Dominion University

Series

2013

Nanosecond pulsed electric fields

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Full-Text Articles in Medicine and Health Sciences

Bioelectrics In Basic Science And Medicine: Impact Of Electric Fields On Cellular Structures And Functions, Stephen J. Beebe Jan 2013

Bioelectrics In Basic Science And Medicine: Impact Of Electric Fields On Cellular Structures And Functions, Stephen J. Beebe

Bioelectrics Publications

Bioelectrics is a new interdisciplinary field that investigates electric field effects on cell membranes and other cellular components. It incorporates four main technologies, including electroporation, nanosecond pulsed electric fields, picosecond pulsed electric fields and cold plasmas. The parent technology in Bioelectrics is electroporation, which uses milli- and/or micro-second electric pulses to permeabilize cells and tissues, for delivery of membrane impermeable molecules. It is now being used for electro-gene delivery, with vascular endothelial growth factor, for revascularization in wound healing and cardiovascular and peripheral vascular disease. Plasmids expressing IL-12 are being delivered for immune system activation in melanoma treatment, now in …