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- Keyword
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- Cerebrovascular;; CNS;; Infections;; Neurocysticercosis;; Cryptococcus (1)
- Vitamin D receptors;; Aspartyl protease;; NF-KAPPA-B;; VITAMIN-D-RECEPTOR;; VACUOLAR H+-ATPASE;; (PRO)RENIN RECEPTOR;; GENE-EXPRESSION;; RENIN/PRORENIN RECEPTOR;; DOWN-REGULATION;; KIDNEY-DISEASE;; D ANALOG;; PROTEASE;; Cell Biology;; Hematology;; Immunology (1)
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Renin Modulates Hiv Replication In T Cells, N. Chandel, K. Ayasolla, X. Q. Lan, P. Rai, J. Mikulak, M. Husain, A. Malhotra, J. Mcgowan, P. C. Singhal
Renin Modulates Hiv Replication In T Cells, N. Chandel, K. Ayasolla, X. Q. Lan, P. Rai, J. Mikulak, M. Husain, A. Malhotra, J. Mcgowan, P. C. Singhal
Journal Articles
HIV is known to subvert cellular machinery to enhance its replication. Recently, HIV has been reported to enhance TC renin expression. We hypothesized that HIV induces and maintains high renin expression to promote its own replication in TCs. Renin enhanced HIV replication in TCs in a dose-dependent manner. (P)RR-deficient TCs, as well as those lacking renin, displayed attenuated NF-B activity and HIV replication. TCs treated with renin and Hpr displayed activation of the (P)RR-PLZF protein signaling cascade. Renin, HIV, and Hpr activated the PI3K pathway. Both renin and Hpr cleaved Agt (a renin substrate) to Ang I and also cleaved …
Central Nervous System Infections Masquerading As Cerebrovascular Accidents: Case Series And Review Of Literature, L. Hayes, P. Malhotra
Central Nervous System Infections Masquerading As Cerebrovascular Accidents: Case Series And Review Of Literature, L. Hayes, P. Malhotra
Journal Articles
AbstractIntroduction Central nervous system (CNS) infections can have various presentations including Cerebrovascular accidents (CVA) which may go unrecognized as a presentation of infection. We describe three cases of different CNS infections complicated by CVA. Presentation Case 1 describes a 27-year-old man, presenting with symptoms consistent with a transient ischemic attack found to have racemose neurocysticercosis. Case 2 describes a 55-year-old man with low grade fevers for 4 weeks accompanied by visual and gait disturbances and delayed speech diagnosed with multiple small left thalamocapsular and superior cerebellar infarcts secondary to cryptococcal meningitis. The third case describes a man with pneumococcal meningitis …
Management Of Serology Negative Human Hepatic Hydatidosis (Caused By Echinococcus Granulosus) In A Young Woman From Bangladesh In A Resource-Rich Setting: A Case Report, Daniel O. Griffin, Henry J. Donaghy, Barbara Edwards
Management Of Serology Negative Human Hepatic Hydatidosis (Caused By Echinococcus Granulosus) In A Young Woman From Bangladesh In A Resource-Rich Setting: A Case Report, Daniel O. Griffin, Henry J. Donaghy, Barbara Edwards
Journal Articles
Human cystic echinococcosis (hydatidosis) is a parasitic zoonosis with almost complete worldwide distribution. Echinococcus granulosus, the dog tapeworm, causes hydatidosis which accounts for 95% of human echinococcosis. Although this tapeworm is found in dogs as a definitive host and a number of intermediate hosts, humans are often infected from close contact with infected dogs. Humans are not part of the parasitic lifecycle and serve as accidental hosts. Hydatidosis is an important consideration in the differential diagnosis of hepatic cysts in individuals from endemic areas. Clinicians should be aware of the long incubation period, the high frequency of negative serological tests, …