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Dna Methylation Pattern Of Cpg Site In The Promoter Region Of Calca-Alpha Gene As A Putative Epigenetic Biomarker In Neonatal Sepsis- A Prospective Observational Study In South India, Rudra Rupesh Reddy Narsapurapu, Deepti Thandaveshwara, Anshu Kumar Yadav, Akila Prashant
Dna Methylation Pattern Of Cpg Site In The Promoter Region Of Calca-Alpha Gene As A Putative Epigenetic Biomarker In Neonatal Sepsis- A Prospective Observational Study In South India, Rudra Rupesh Reddy Narsapurapu, Deepti Thandaveshwara, Anshu Kumar Yadav, Akila Prashant
Digital Journal of Clinical Medicine
Background: Recently, several studies have been reported on epigenetic modifications of DNA as a predisposing factor for several diseases among neonates and adults. Here we aimed to study the changes in the DNA methylation pattern in the promoter region of the CALCA gene among the neonates suspected to have sepsis in a tertiary care hospital.
Methodology: All the neonates suspected to have sepsis based on the inclusion criteria during the study period were included in the study as cases. Normal healthy neonates were included in the study as controls. Positive cases were isolated from suspected cases based on …