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Full-Text Articles in Medicine and Health Sciences

Identification Of Plasma Lipid Biomarkers In Alzheimer's Disease, Rhona Creegan Jan 2014

Identification Of Plasma Lipid Biomarkers In Alzheimer's Disease, Rhona Creegan

Theses: Doctorates and Masters

Alzheimer’s disease (AD), the commonest form of dementia, is a chronic, progressive neurodegenerative disease which manifests clinically as a slow global decline in cognitive function, including deterioration of memory, reasoning, abstraction, language and emotional stability, culminating in a patient with end-stage disease, totally dependent on custodial care. With an ageing population, there is predicted to be a marked increase in the number of people diagnosed with AD in the coming decades, making this a significant challenge to socio-economic policy and aged care. Currently there is no cure for AD and while current therapies may temporarily ameliorate symptoms, death usually occurs …


Plasma Insulin-Degrading Enzyme: Characterisation And Evaluation As A Potential Biomarker For Alzheimer's Disease, Michelle Tegg Jan 2014

Plasma Insulin-Degrading Enzyme: Characterisation And Evaluation As A Potential Biomarker For Alzheimer's Disease, Michelle Tegg

Theses: Doctorates and Masters

Alzheimer’s disease (AD) is increasing in prevalence due to increasing lifespan and altered lifestyle. It is the fourth major cause of death in Western countries, resulting in significant economic and social impact (Von Strauss, et al., 1999; Goate, 1997). There are no blood biomarkers currently accepted for the diagnosis of AD, and the identification of suitable biomarkers would eventually reduce the necessity for invasive, expensive and slow diagnostic procedures, as well as facilitate prognostic studies. An AD blood test would decrease the need for delaying diagnosis due to ambivalent presentation, and allow therapeutic intervention to commence at an earlier …


Fall Risk Assessment : A Prospective Investigation Of Nurses' Clinical Judgement And Risk Assessment Tools In Predicting Patient Falls In An Acute Care Setting, Helen Myers Jan 2003

Fall Risk Assessment : A Prospective Investigation Of Nurses' Clinical Judgement And Risk Assessment Tools In Predicting Patient Falls In An Acute Care Setting, Helen Myers

Theses: Doctorates and Masters

Falls are a significant problem in acute care, hospital settings, and can have serious consequences, especially for older patients. Fall prevention has therefore been recognised as an important area for research and intervention. In order to target interventions and use resources effectively, a major strategy of many fall prevention programmes has been the development and/or use of risk assessment tools to identify patients who are at high risk of falling. Although many tools have been developed, few have been rigorously tested, and there is currently no evidence to support the clinical utility of fall risk assessment tools. There is a …


A Comparison Between Conventional And Holistic Exercise Interventions On Physiological Function In The Elderly, Gavin R. Mccormack Jan 2003

A Comparison Between Conventional And Holistic Exercise Interventions On Physiological Function In The Elderly, Gavin R. Mccormack

Theses: Doctorates and Masters

Aging is characterised by a decline in physiological function. The rate of this decline can depend on certain lifestyle factors, genetics, and the environment. Although life expectancy is slowly increasing, there is a need to reduce the time spent in debilitated, and non-independent states by elderly individuals. Preventive measures need to be implemented to reduce dependency and improve the quality of life for elderly individuals. One such preventive and remedial measure is the use of exercise and physical activity. Because limited exercise prescription exists for the elderly population, there is a need to determine the effectiveness of exercise interventions that …


A Qualitative Study Of The Impact Of Hip Fracture In The Elderly Population, Stephanie Anne Price Jan 2000

A Qualitative Study Of The Impact Of Hip Fracture In The Elderly Population, Stephanie Anne Price

Theses: Doctorates and Masters

The social, emotional and economic impact of falling in the elderly population is significant. Falls are the leading cause of injury related deaths and hospitalisation amongst people aged 65 years and older, a major factor in their morbidity and mortality rates. Post fall sequelae can have major ramifications that include reduction or avoidance of activities, attributable to an enduring fear of future falls. Twenty-three older people who had fallen in the community were located via hospital records and invited to participate in the study. Subjective accounts of the impact of falling and sustaining a hip fracture were obtained by means …


The Use Of The Cognitive Status Examination In Detecting Cognitive Impairment In Elderly People, Geoff Mccann Jan 2000

The Use Of The Cognitive Status Examination In Detecting Cognitive Impairment In Elderly People, Geoff Mccann

Theses: Doctorates and Masters

Dementia is a growing social problem in Australia because as the population ages, the incidence of dementia increases. While the prevalence rates are only about I% at age 65, they double every five years until by 85 years of age the rate is over 24%. It is expected that by the year 2030, the number of elderly people with dementia will increase by 200%. Dementia is easily recognized in its advanced stages but can be overlooked in the early phase. Family members, care-givers and even the treating medical practitioner may mistakenly attribute the early decline in mental function to the …


The Lived Experience Of The Aged Care Nurse, Christine Martin Jan 1996

The Lived Experience Of The Aged Care Nurse, Christine Martin

Theses: Doctorates and Masters

The purpose of this phenomenological study was to describe and interpret the common, shared meanings of the experience of aged care nursing from the perspective of the registered nurse working in a nursing home. There are insufficient registered nurses being attracted into aged care, with resulting difficulties in maintaining regular staffing levels in nursing homes. Previous studies conducted in Australia have predominantly used quantitative research methods to investigate various influences QD the recruitment and retention of aged care nurses. These studies do not take into account the practitioners' perceptions of their experience of aged care nursing. A purposive sample of …