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Genetic And Environmental (Physical Fitness And Sedentary Activity) Interaction Effects On Cardiometabolic Risk Factors In Mexican American Children And Adolescents, Rector Arya, Vidya S. Farook, Sharon P. Fowler, Sobha Puppala, Geetha Chittoor, Roy G. Resendez, Srinivas Mummidi, Jairam Vanamala, Laura Almasy, Joanne E. Curran, Donna M. Lehman, Christopher P. Jenkinson, Jane L. Lynch, Ralph A. Defronzo, John Blangero, Ravindranath Duggirala, Vincent P. Diego
Genetic And Environmental (Physical Fitness And Sedentary Activity) Interaction Effects On Cardiometabolic Risk Factors In Mexican American Children And Adolescents, Rector Arya, Vidya S. Farook, Sharon P. Fowler, Sobha Puppala, Geetha Chittoor, Roy G. Resendez, Srinivas Mummidi, Jairam Vanamala, Laura Almasy, Joanne E. Curran, Donna M. Lehman, Christopher P. Jenkinson, Jane L. Lynch, Ralph A. Defronzo, John Blangero, Ravindranath Duggirala, Vincent P. Diego
School of Medicine Publications and Presentations
Knowledge on genetic and environmental (G × E) interaction effects on cardiometabolic risk factors (CMRFs) in children is limited. The purpose of this study was to examine the impact of G × E interaction effects on CMRFs in Mexican American (MA) children (n = 617, ages 6–17 years). The environments examined were sedentary activity (SA), assessed by recalls from “yesterday” (SAy) and “usually” (SAu) and physical fitness (PF) assessed by Harvard PF scores (HPFS). CMRF data included body mass index (BMI), waist circumference (WC), fat mass (FM), fasting insulin (FI), homeostasis model of assessment—insulin resistance (HOMA‐IR), high‐density lipoprotein cholesterol …