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Gastroenterology

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Effects Of Cromolyn On Inflammatory Bowel Disease Of Childhood, Yvette Piovanetti May 1978

Effects Of Cromolyn On Inflammatory Bowel Disease Of Childhood, Yvette Piovanetti

Yale Medicine Thesis Digital Library

Methods and Materials: Twelve children with CIBD (7 with CUC and 5 with Crohn's) entered a trial with Cromolyn Sodium. The patient groups consisted mostly of those who had been treated with steroids over a 1-year period without suppression of disease activity, and in whom steroids could not be tapered without exacerbation. On commencement of Cromolyn therapy, steroid dosages ranged from 5-60 mg. q.d. (mean dose 30 mg. q.d.). Multiple complications of steroid therapy were observed in this group. Linear growth retardation was exhibited by 5 patients, 2 with Crohn's and 3 with CUC. One of the patients with CUC …