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Articles 1 - 7 of 7
Full-Text Articles in Medicine and Health Sciences
Sleep And Alzheimer’S Disease: A Critical Examination Of The Risk That Sleep Problems Or Disorders Particularly Obstructive Sleep Apnea Pose Towards Developing Alzheimer’S Disease, Omonigho A. Michael Bubu
Sleep And Alzheimer’S Disease: A Critical Examination Of The Risk That Sleep Problems Or Disorders Particularly Obstructive Sleep Apnea Pose Towards Developing Alzheimer’S Disease, Omonigho A. Michael Bubu
USF Tampa Graduate Theses and Dissertations
This dissertation is a critical examination of the relationship between sleep problems and/or disorders, particularly Obstructive Sleep Apnea (OSA) and Alzheimer Disease (AD). First, I conducted an exhaustive systematic review of existing literature, and identified gaps in research that led to specific research aims. For the first aim, I conducted the first ever-published meta-analysis examining sleep, cognitive decline and AD, providing an aggregate effect of sleep on AD. Second, focusing on OSA, I conducted a study examining OSA’s effect on longitudinal changes on AD biomarkers in cognitive normal, MCI and AD subjects, using data from the Alzheimer Disease Neuroimaging Initiative …
Ambient Ozone And Cadmium As Risk Factors For Congenital Diaphragmatic Hernia, Rema Ramakrishnan
Ambient Ozone And Cadmium As Risk Factors For Congenital Diaphragmatic Hernia, Rema Ramakrishnan
USF Tampa Graduate Theses and Dissertations
Congenital diaphragmatic hernia (CDH) results from a defect in the diaphragm through which abdominal contents enter the thorax displacing the heart and the lungs. This causes lung hypoplasia and varying degrees of pulmonary hypertension resulting in high rates of morbidity and mortality. Though CDH has a prevalence rate of 2.61 per 10,000 live births it is an expensive birth defect with an estimated annual cost of nearly $250 million for all CDH survivors. Maternal exposure to air pollutants have not been studied as risk factors for CDH in humans. Ambient ozone has been found to be risk factors for certain …
The Effects Of Maternal Folate On Fetal Brain And Body Size Among Smoking Mothers, Korede K. Adegoke
The Effects Of Maternal Folate On Fetal Brain And Body Size Among Smoking Mothers, Korede K. Adegoke
USF Tampa Graduate Theses and Dissertations
The adverse effects of maternal smoking on infant mortality and morbidity has been well documented in the literature. Maternal tobacco use is causally associated with fetal growth restriction and correlates negatively with folate intake and metabolism. Studies have examined the association between smoking and folate levels during pregnancy, but very few have assessed this relationship using objective and accurate measures of both variables. Furthermore, despite evidence of a causal association between smoking in pregnancy and intrauterine growth restriction, and a plausible relationship between tobacco use and low maternal folate which is required for optimal fetal growth, no experimental study has …
Ambient Benzene And Pm2.5 Exposure During Pregnancy: Examining The Impact Of Exposure Assessment Decisions On Associations Between Birth Defects And Air Pollution, Jean Paul Tanner
Ambient Benzene And Pm2.5 Exposure During Pregnancy: Examining The Impact Of Exposure Assessment Decisions On Associations Between Birth Defects And Air Pollution, Jean Paul Tanner
USF Tampa Graduate Theses and Dissertations
In the United States, approximately 3% of infants are diagnosed with a major birth defect each year. Whereas prevention efforts have led to decreases in some birth defects, the cause of approximately 70% of birth defects remains unknown. More recently, there has been increasing concern regarding exposures to environmental agents, such as air pollution during pregnancy, and the risk of birth defects. Over the past decade, there has been an increase in research studies examining the association between air pollution and birth defects. The results have been inconsistent, with some studies reporting that higher levels of exposure from the same …
Deployment, Post-Traumatic Stress Disorder And Hypertensive Disorders Of Pregnancy Among U.S. Active-Duty Military Women, Michelle C. Nash
Deployment, Post-Traumatic Stress Disorder And Hypertensive Disorders Of Pregnancy Among U.S. Active-Duty Military Women, Michelle C. Nash
USF Tampa Graduate Theses and Dissertations
Introduction. Today women comprise 15% of the U.S. active-duty military, but are often overlooked in research of the Armed Forces. While some of the challenges faced by women are similar to men, they encounter unique stressors related to childcare while deployed, sexual harassment and assault, and gynecological needs. Women are also more likely than men to develop post-traumatic stress disorder (PTSD). Both stress and PTSD have been linked to the development of chronic hypertension and some adverse birth outcomes. We hypothesized that post-9/11/2001 era military women who deployed or who had indicators of PTSD would be at greater risk of …
Severe Maternal Morbidity In Florida: Risk Factors And Determinants Of The Increasing Rate, Lindsay Shively Womack
Severe Maternal Morbidity In Florida: Risk Factors And Determinants Of The Increasing Rate, Lindsay Shively Womack
USF Tampa Graduate Theses and Dissertations
Severe maternal morbidity generally refers to the most severe complications of pregnancy and includes: hemorrhage, embolism, acute renal failure, stroke, acute myocardial infarction, and other complications. These complications affect more than 50,000 women in the United States every year, with rates significantly increasing from 1998 to 2011. In an effort to reduce these increasing complication rates, clinicians and researchers have emphasized the need to identify potential modifiable risk factors for severe maternal morbidity, and the need to study the relationships between these risk factors and severe maternal morbidity. The overall goal of this study is to improve the understanding of …
Neighborhood Deprivation, Food Insecurity And Gestational Weight Gain, Sabrina Luke
Neighborhood Deprivation, Food Insecurity And Gestational Weight Gain, Sabrina Luke
USF Tampa Graduate Theses and Dissertations
Gestational weight gain outside the recommended ranges puts women at risk for pregnancy complications and adverse birth outcomes. Food insecurity and environmental factors including neighborhood deprivation may influence gestational weight gain. This research 1) examines the impact of neighborhood deprivation on gestational weight gain, 2) identifies if the association varies by selected maternal characteristics, 3) examines the relationship between food insecurity and gestational weight gain, 4) determines if stress mediates the relationship between food insecurity and gestational weight gain, and 5) examines whether selected maternal characteristics mediate this relationship. The research was conducted through the analysis of the Pregnancy Risk …