Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Aluminum (1)
- Aluminum Hydroxide (1)
- Aluminum Oxide (1)
- Aluminum nanoparticles (1)
- Alzheimer's disease (1)
-
- Animal (1)
- Animals (1)
- Antiperspirants (1)
- Autoimmune disease (1)
- Breast cancer (1)
- Carcinogenesis (1)
- Cardiovascular System (1)
- Central Nervous System (1)
- Disease Models (1)
- Disease Models, Animal (1)
- Dose-Response Relationship (1)
- Dose-Response Relationship, Drug (1)
- Drug (1)
- Encephalopathy (1)
- Endocrine System (1)
- Epidemiology (1)
- Europe (1)
- Gastrointestinal Tract (1)
- Guidelines as Topic (1)
- Humans (1)
- Immune checkpoint inhibitors (1)
- Kidney (1)
- Liver (1)
- Lung cancer (1)
- Microcytic anemia (1)
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Immune Checkpoint Inhibition And The Prevalence Of Autoimmune Disorders Among Patients With Lung And Renal Cancer, Sherif M. El-Refai
Immune Checkpoint Inhibition And The Prevalence Of Autoimmune Disorders Among Patients With Lung And Renal Cancer, Sherif M. El-Refai
Pharmaceutical Sciences Faculty Publications
PURPOSE: Immune checkpoint inhibition reactivates the immune response against cancer cells in multiple tissue types and has been shown to induce durable responses. However, for patients with autoimmune disorders, their conditions can worsen with this reactivation. We sought to identify, among patients with lung and renal cancer, how many harbor a comorbid autoimmune condition and may be at risk of worsening their condition while on immune checkpoint inhibitors such as nivolumab and pembrolizumab.
METHODS: An administrative health care claims database, Truven MarketScan, was used to identify patients diagnosed with lung and renal cancer from 2010 to 2013. We assessed patients …
Systematic Review Of Potential Health Risks Posed By Pharmaceutical, Occupational And Consumer Exposures To Metallic And Nanoscale Aluminum, Aluminum Oxides, Aluminum Hydroxide And Its Soluble Salts, Calvin C. Willhite, Nataliya A. Karyakina, Robert A. Yokel, Nagarajkumar Yenugadhati, Thomas M. Wisniewski, Ian M. F. Arnold, Franco Momoli, Daniel Krewski
Systematic Review Of Potential Health Risks Posed By Pharmaceutical, Occupational And Consumer Exposures To Metallic And Nanoscale Aluminum, Aluminum Oxides, Aluminum Hydroxide And Its Soluble Salts, Calvin C. Willhite, Nataliya A. Karyakina, Robert A. Yokel, Nagarajkumar Yenugadhati, Thomas M. Wisniewski, Ian M. F. Arnold, Franco Momoli, Daniel Krewski
Pharmaceutical Sciences Faculty Publications
Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); it is also present in ambient and occupational airborne particulates. Existing data underscore the importance of Al physical and chemical forms in relation to its uptake, accumulation, and systemic bioavailability. The present review represents a systematic examination of the peer-reviewed literature on the adverse health effects of Al materials published since a previous critical evaluation compiled by Krewski et al. (2007).
Challenges encountered in carrying out the present review reflected the experimental use of different physical …