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Medicine and Health Sciences Commons

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Epidemiology

David M. Mannino

Cardiovascular Disease

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The Association Of Adverse Pregnancy Events And Cardiovascular Disease In Women 50 Years Of Age And Older, Sara M. Freibert, David M. Mannino, Heather Bush, Leslie J. Crofford Feb 2011

The Association Of Adverse Pregnancy Events And Cardiovascular Disease In Women 50 Years Of Age And Older, Sara M. Freibert, David M. Mannino, Heather Bush, Leslie J. Crofford

David M. Mannino

Objective: This study investigates the association between a prior history of pregnancy complications and cardiovascular disease (CVD) among Kentucky women aged ≥50 years.

Methods: Data were analyzed from participants (n = 3909) in the Kentucky Women's Health Registry (2006–2008). Primary outcomes were self-reported prevalence of CVD, including angina, heart attack, heart failure, and arrhythmia. Pregnancy complications used as predictors were preterm labor, preeclampsia, gestational diabetes mellitus (GDM), and third trimester bleeding. Logistic regression analyses were conducted to determine associations between prevalence of CVD and pregnancy complications, controlling for age, education, and smoking status.

Results: Overall, 199 (5.1%) women reported angina, …