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Epidemiology

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Cancer

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Full-Text Articles in Medicine and Health Sciences

What Are The Factors That Predict Outcome At Relapse After Previous Esophagectomy And Adjuvant Therapy In High-Risk Esophageal Cancer?, Edward Yu, P. Tai, R. Malthaner, L. Stitt, G. Rodrigues, R. Dar, B. Yaremko, J. Younus, M. Sanatani, M. Vincent, B. Dingle, D. Fortin, R. Inculet Oct 2010

What Are The Factors That Predict Outcome At Relapse After Previous Esophagectomy And Adjuvant Therapy In High-Risk Esophageal Cancer?, Edward Yu, P. Tai, R. Malthaner, L. Stitt, G. Rodrigues, R. Dar, B. Yaremko, J. Younus, M. Sanatani, M. Vincent, B. Dingle, D. Fortin, R. Inculet

Edward Yu

OBJECTIVES: The present study investigated factors affecting outcome at relapse after previous surgery and adjuvant chemoradiation (crt) in high-risk esophageal cancer patients. PATIENTS AND METHODS: From 1989 to 1999, we followed high-risk resected esophageal cancer patients who had completed postoperative crt therapy. Patients who relapsed with a disease-free interval of less than 3 months were treated with palliative crt when appropriate. Patients with a disease-free interval of 3 months or more were treated with best supportive care. Post-recurrence survival was estimated using the Kaplan-Meier technique, and statistical comparisons were made using log-rank chi-square tests and Cox regression. RESULTS: Of the …


Cancer Disparities Among American Indians And Alaska Natives, Lisa M. Lines Dec 2007

Cancer Disparities Among American Indians And Alaska Natives, Lisa M. Lines

Lisa M. Lines

The burden of cancer on AIAN patients is a complicated one. The low incidence rates among AIANs may be more a reflection of the low screening rates than a true lack of incident cancers in this population, and while death rates are related to incidence, 5-year survival rates are more related to stage at detection and receipt of treatment. The cancer burden is more severe for AIAN patients in part because of barriers to access, including financial, cultural, and geographic factors. Although some efforts have been made to address these disparities, a critical lack of studies and data hampers efforts …