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Gestational Weight Gain And Child Adiposity At Age 3 Years, Emily Oken, Elsie M. Taveras, Ken P. Kleinman, Janet W. Rich-Edwards, Matthew W. Gillman

Public Health Department Faculty Publication Series

OBJECTIVE

The purpose of this study was to examine the associations of gestational weight gain with child adiposity.

STUDY DESIGN

Using multivariable regression, we studied associations of total gestational weight gain and weight gain according to 1990 Institute of Medicine guidelines with child outcomes among 1044 mother-child pairs in Project Viva.

RESULTS

Greater weight gain was associated with higher child body mass index z-score (0.13 units per 5 kg [95% CI, 0.08, 0.19]), sum of subscapular and triceps skinfold thicknesses (0.26 mm [95% CI, 0.02, 0.51]), and systolic blood pressure (0.60 mm Hg [95% CI, 0.06, 1.13]). Compared with inadequate …

Milk Consumption And The Prepubertal Somatotropic Axis, Janet W. Rich-Edwards, Davaasambuu Ganmaa, Michael N. Pollak, Erika K. Nakamoto, Ken Kleinman, Uush Tserendolgor, Walter C. Willett, A Lindsay Frazier

Public Health Department Faculty Publication Series

Background

Nutrients, hormones and growth factors in dairy foods may stimulate growth hormone (GH), insulin-like growth factor I (IGF-I), and raise the ratio of IGF-I to its binding protein, IGFBP-3. We conducted pilot studies in Mongolia and Massachusetts to test the extent to which milk intake raised somatotropic hormone concentrations in prepubertal children.

Methods

In Ulaanbaatar, we compared plasma levels before and after introducing 710 ml daily whole milk for a month among 46 10–11 year old schoolchildren. In a randomized cross-over study in Boston, we compared plasma hormone levels of 28 6–8 year old girls after one week of …