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Weathering The Storm: Climate Change, Vulnerability, And Adaptation In Bangladesh, Justin Guay

Electronic Theses and Dissertations

The world is guaranteed a certain level of climate change due to the emissions already released into the atmosphere. Therefore, adaptation to climate change is necessary. Increases in diarrheal disease and malnutrition due to climate change are analyzed for Bangladesh. Relative risks determined by the World Health Organization, estimates obtained from agricultural models, and migration estimates are utilized to determine the costs associated with each of these diseases, as well as reductions in rice production and increases in urban migration. It is found that climate change will create additional costs for treating each of these diseases that equal .05% of …

Folate Deficiency, Hyperhomocysteinemia, Low Urinary Creatinine, And Hypomethylation Of Leukocyte Dna Are Risk Factors For Arsenic-Induced Skin Lesions, Richard Pilsner, Xinhua Liu, Habibul Ahsan, Vesna Ilievski, Vesna Slavkovich, Diane Levy, Pam Factor-Litvak, Joseph Graziano, Mary Gamble

J. Richard Pilsner

Background

Arsenic methylation relies on folate-dependent one-carbon metabolism and facilitates urinary As elimination. Clinical manifestations of As toxicity vary considerably among individuals and populations, and poor methylation capacity is thought to confer greater susceptibility.

Objective

After determining that folate deficiency, hyperhomocysteinemia, and low urinary creatinine are associated with reduced As methylation, and that As exposure is associated with increased genomic methylation of leukocyte DNA, we asked whether these factors are associated with As-induced skin lesion risk among Bangladeshi adults.

Methods

We conducted a nested case–control study of 274 cases who developed lesions 2 years after recruitment, and 274 controls matched …