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Full-Text Articles in Medicine and Health Sciences

Impact Of Poor Air Quality On Chronic Respiratory Problems Among The Elderly, James D. Blando, My Ngoc Nguyen, Manasi Sheth-Chandra, Muge Akpinar-Elci Jan 2015

Impact Of Poor Air Quality On Chronic Respiratory Problems Among The Elderly, James D. Blando, My Ngoc Nguyen, Manasi Sheth-Chandra, Muge Akpinar-Elci

Community & Environmental Health Faculty Publications

[First Paragraph] There is a considerable body of evidence that suggests poor ambient air quality contributes to increased mortality and morbidity. 1,2,3,4,5 The impact of ambient air quality on different segments of the general population, including children and among the elderly has also been investigated.6,7,8,9 In light of the well documented public health significance of air pollution, it is imperative that investigators continue to evaluate details regarding the impact of poor air quality. In particular, it is interesting to note that some research has indicated an increased risk of the young and the elderly being admitted to the hospital …


Are Semen Quality Parameters Sufficient For Biomonitoring Spermatozoa Dna Integrity And Oxidatively Damaged Dna, Hueiwang Anna Jeng, Ruei-Nian Li, Wen-Yi Lin Jan 2015

Are Semen Quality Parameters Sufficient For Biomonitoring Spermatozoa Dna Integrity And Oxidatively Damaged Dna, Hueiwang Anna Jeng, Ruei-Nian Li, Wen-Yi Lin

Community & Environmental Health Faculty Publications

The present study aimed to investigate the relationship between semen quality parameters and DNA integrity, and determine whether semen quality parameters could serve as a reliable biomarker for monitoring sperm DNA damage. Conventional semen parameters from a total of 202 male human subjects were analyzed. DNA fragmentation and 8-oxo-7,8-dihydro-2′- deoxyguanosine (8-oxoGuo) were used to assess sperm DNA integrity. DNA fragmentation was analyzed by the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay and sperm chromatin structure assay (SCSA), while 8-oxodGuo was quantified by the liquid chromatography/tandem mass spectrometry (LC-MS/MS) coupled with an on-line solid phase system. The levels of …