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Engineering

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Selected Works

2016

Articles 1 - 4 of 4

Full-Text Articles in Medicine and Health Sciences

Deriving An Indoor Environmental Index For Portuguese Office Buildings, João F. Gomes Nov 2016

Deriving An Indoor Environmental Index For Portuguese Office Buildings, João F. Gomes

João F Gomes

No abstract provided.

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Developing Hyperpolarized Silicon Particles For In Vivo Mri Targeting Of Ovarian Cancer, Nicholas Whiting, Jingzhe Hu, Niki M. Zacharias, Ganesh L. R. Lokesh, David E. Volk, David G. Menter, Rajesha Rupaimoole, Rebecca Previs, Anil K. Sood, Pratip Bhattacharya Aug 2016

Developing Hyperpolarized Silicon Particles For In Vivo Mri Targeting Of Ovarian Cancer, Nicholas Whiting, Jingzhe Hu, Niki M. Zacharias, Ganesh L. R. Lokesh, David E. Volk, David G. Menter, Rajesha Rupaimoole, Rebecca Previs, Anil K. Sood, Pratip Bhattacharya

Nicholas Whiting

Silicon-based nanoparticles are ideally suited for use as biomedical imaging agents due to their biocompatibility, biodegradability, and simple surface chemistry that facilitates drug loading and targeting. A method of hyperpolarizing silicon particles using dynamic nuclear polarization, which increases magnetic resonance imaging signals by several orders-of-magnitude through enhanced nuclear spin alignment, has recently been developed to allow silicon particles to function as contrast agents for in vivo magnetic resonance imaging. The enhanced spin polarization of silicon lasts significantly longer than other hyperpolarized agents (tens of minutes, whereas <1  min for other species at room temperature), allowing a wide range of potential …

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Should Expectations About The Rate Of New Antiretroviral Drug Development Impact The Timing Of Hiv Treatment Initiation And Expectations About Treatment Benefits?, Amin Khademi, R. Scott Braithwaite, Denis Saure, Andrew J. Schaefer, Kimberly Nucifora, Mark S. Roberts Apr 2016

Should Expectations About The Rate Of New Antiretroviral Drug Development Impact The Timing Of Hiv Treatment Initiation And Expectations About Treatment Benefits?, Amin Khademi, R. Scott Braithwaite, Denis Saure, Andrew J. Schaefer, Kimberly Nucifora, Mark S. Roberts

Amin Khademi

Background: Many analyses of HIV treatment decisions assume a fixed formulary of HIV drugs. However, new drugs are approved nearly twice a year, and the rate of availability of new drugs may affect treatment decisions, particularly when to initiate antiretroviral therapy (ART).

Objectives: To determine the impact of considering the availability of new drugs on the optimal initiation criteria for ART and outcomes in patients with HIV/AIDS.

Methods: We enhanced a previously described simulation model of the optimal time to initiate ART to incorporate the rate of availability of new antiviral drugs. We assumed that the future rate of availability …

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Adaptation Of Forward Military Airspace Management For Civilian Uas Emergency Services Operations, John C. Griffith Ph.D., Brent A. Terwilliger Ph.D. Jan 2016

Adaptation Of Forward Military Airspace Management For Civilian Uas Emergency Services Operations, John C. Griffith Ph.D., Brent A. Terwilliger Ph.D.

John Griffith

Potential use of unmanned aircraft system (UAS) to save lives, improve safety, and protect property has generated preliminary research in three major areas of the fire service, including aviation, structure and wildland scenarios.   Roadblocks to the effective use of UAS technology will be discussed with a focus on command, control, and communication (C3) issues and governmental actions to limit the use of UAS due to aviation integration safety concerns.  The results of this research will include presented adaptation of Joint Terminal Air Controller (JTAC) methodology, typically used for military command and control (Deptula & Dahl, 2003), for civilian emergency services …

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