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Experimental Data Extraction And In Silico Prediction Of The Estrogenic Activity Of Renewable Replacements For Bisphenol A., Huixiao Hong, Benjamin G Harvey, Giuseppe R Palmese, Joseph F. Stanzione Iii, Hui Wen Ng, Sugunadevi Sakkiah, Weida Tong, Joshua M Sadler
Experimental Data Extraction And In Silico Prediction Of The Estrogenic Activity Of Renewable Replacements For Bisphenol A., Huixiao Hong, Benjamin G Harvey, Giuseppe R Palmese, Joseph F. Stanzione Iii, Hui Wen Ng, Sugunadevi Sakkiah, Weida Tong, Joshua M Sadler
Henry M. Rowan College of Engineering Departmental Research
Bisphenol A (BPA) is a ubiquitous compound used in polymer manufacturing for a wide array of applications; however, increasing evidence has shown that BPA causes significant endocrine disruption and this has raised public concerns over safety and exposure limits. The use of renewable materials as polymer feedstocks provides an opportunity to develop replacement compounds for BPA that are sustainable and exhibit unique properties due to their diverse structures. As new bio-based materials are developed and tested, it is important to consider the impacts of both monomers and polymers on human health. Molecular docking simulations using the Estrogenic Activity Database in …