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Full-Text Articles in Medicine and Health Sciences

The Effect Of Fatigue On Lower Extremity Joint Kinematics And Performance, Sarah Alloto Apr 2023

The Effect Of Fatigue On Lower Extremity Joint Kinematics And Performance, Sarah Alloto

Undergraduate Distinction Papers

Within recent years there has been an increase in the number of anterior cruciate ligament (ACL) injuries within female athletes (Learning how ACL, 2022). The ACL is a ligamentous structure within the knee that connects the femur and the tibia (Mayo, 2022). Its primary function is to provide stability, prevent the tibia from excessive anterior translation, and provide proprioceptive input for the lower limb (Mayo, 2022). ACL injuries are multifactorial in nature, meaning they can be the result of faulty biomechanics, individual genetic predisposition, or environmental factors (Alentorn- Geli et al., 2009). ACL injuries can be classified into two categories: …


Mir125a As Molecular Target Of Vitamin D Mediated Inhibition Of Cd4+ T Cell Differentiation Into Th17 Cells In Mrl/Lpr Lupus-Prone Mice, Miranda Hilt Apr 2023

Mir125a As Molecular Target Of Vitamin D Mediated Inhibition Of Cd4+ T Cell Differentiation Into Th17 Cells In Mrl/Lpr Lupus-Prone Mice, Miranda Hilt

Undergraduate Distinction Papers

The dynamic function of vitamin D in an array of immunomodulatory and anti-inflammatory mechanisms and its implication in the pathogenesis of autoimmune diseases has been the topic of much recent scholarship. Here I attempt to elucidate the molecular mechanism of vitamin D-mediated inhibition of the differentiation of CD4+ T cells into pro-inflammatory Th17 cells in MRL/lpr lupus prone mice by investigating how miR-125a expression is affected by dietary modulation of cholecalciferol (vitamin D3). MRL/MpJ and MRL/lpr mice were split into three experimental groups and fed specially formulated diets that varied in their concentrations of vitamin D. …


Cadaveric Endoscopic Gastrocnemius Recession Procedures To Identify Vital Anatomical Structures And Limit Intraoperative And Post-Operative Complications, Austin Combs Apr 2021

Cadaveric Endoscopic Gastrocnemius Recession Procedures To Identify Vital Anatomical Structures And Limit Intraoperative And Post-Operative Complications, Austin Combs

Undergraduate Distinction Papers

Gastrocnemius equinus contracture plays a role in a multitude of patient pathologies, conditions, and deformities seen in podiatric medicine (Barrett, 2011). Equinus deformity is associated with over 96% of the biomechanically-related foot and ankle pathologies including hallux valgus, metatarsalgia, capsulitis, pes planus, plantar fasciitis, tendonitis, and others (Deheer, 2015). These pathologies are linked with a decreased range of motion in the ankle joint specifically in dorsiflexion. Corrective approaches can be taken to reduce pathology if the patient presents prior to any major deformity. The aim of this study is to better define the location of the small saphenous vein and …


Blue Light And Adult Sleep Outcomes, Andrew Caddas Jan 2021

Blue Light And Adult Sleep Outcomes, Andrew Caddas

Undergraduate Distinction Papers

This study investigated the effects blue light from self-luminous devices has on adult sleeping patterns. We investigated sleep quality and duration qualitatively with a randomized, double-blind, cross-over, placebo-controlled design with a wash-out period. Participants wore blue light blocking lenses or placebo lenses whenever they were using a self-luminous device throughout each day for one week. Each morning, participants filled out a survey to report their number of hours slept, time to fall asleep, and amount of time spent on self-luminous devices. Participants took the Pittsburgh Insomnia Rating Scale (PIRS) at the end of the one week trial (See Appendix A). …